Publications by authors named "David A Candito"

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Discovery and Optimization of Potent, Selective, and Brain-Penetrant 1-Heteroaryl-1-Indazole LRRK2 Kinase Inhibitors for the Treatment of Parkinson's Disease.
David A Candito, Vladimir Simov, Anmol Gulati, Solomon Kattar, Ryan W Chau

J Med Chem· December 2022

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Development of a Flexible and Robust Synthesis of Tetrahydrofuro[3,4-]furan Nucleoside Analogues.
David A Candito, Yingchun Ye, Ryan V Quiroz, Michael H Reutershan, David Witter

J Org Chem· April 2021

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Discovery of Diaminopyrimidine Carboxamide HPK1 Inhibitors as Preclinical Immunotherapy Tool Compounds.
Brandon A Vara, Samuel M Levi, Abdelghani Achab, David A Candito, Xavier Fradera

ACS Med Chem Lett· April 2021

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Lessons from the synthetic chemist nature.
Gerrit Jürjens, Andreas Kirschning, David A Candito

Nat Prod Rep· May 2015

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Development of an intramolecular aryne ene reaction and application to the formal synthesis of (±)-crinine.
David A Candito, Dennis Dobrovolsky, Mark Lautens

J Am Chem Soc· September 2012

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Intramolecular aryne-ene reaction: synthetic and mechanistic studies.
David A Candito, Jane Panteleev, Mark Lautens

J Am Chem Soc· September 2011

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Formal synthesis of nitidine and NK109 via palladium-catalyzed domino direct arylation/N-arylation of aryl triflates.
Mathieu Blanchot, David A Candito, Florent Larnaud, Mark Lautens

Org Lett· March 2011

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SYNTHESIS OF (S,S)-DIISOPROPYL TARTRATE (E)-CROTYLBORONATE AND ITS REACTION WITH ALDEHYDES: (2R,3R,4R)-1,2-DIDEOXY-2-ETHENYL-4,5-O-(1-METHYLETHYLIDENE)-XYLITOL.
Huikai Sun, William R Roush, David A Candito, Mathieu Blanchot, Mark Lautens

Organic Synth· January 2011

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Palladium-catalyzed reductive ortho-arylation: evidence for the decomposition of 1,2-dimethoxyethane and subsequent arylpalladium(II) reduction.
Andrew Martins, David A Candito, Mark Lautens

Org Lett· November 2010

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Exploiting the chemistry of strained rings: synthesis of indoles via domino reaction of aryl iodides with 2H-azirines.
David A Candito, Mark Lautens

Org Lett· August 2010

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Palladium-catalyzed domino direct arylation/N-arylation: convenient synthesis of phenanthridines.
David A Candito, Mark Lautens

Angew Chem Int Ed Engl· October 2009

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Exploiting the divergent reactivity of aryl-palladium intermediates for the rapid assembly of fluorene and phenanthrene derivatives.
Ya-Bin Zhao, Brian Mariampillai, David A Candito, Benoît Laleu, Mengzhou Li

Angew Chem Int Ed Engl· April 2009

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