Publications by authors named "David A Close"

Claim this Profile
M
Miniaturization and characterization of patient derived hepatocellular carcinoma tumor organoid cultures for cancer drug discovery applications.
David A Close, Paul A Johnston

SLAS Discov· January 2025

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
O
Optimization and calibration of 384-well kinetic Ca mobilization assays for the human transient receptor potential cation channels TRPM8, TRPV1, and TRPA1.
David A Close, V Blair Journigan, Paul A Johnston

SLAS Discov· January 2025

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
R
Replacement of the hydroxamic acid group in the selective HDAC8 inhibitor PCI-34051.
Keith Long, David A Close, Paul A Johnston, Donna M Huryn

Bioorg Med Chem Lett· August 2024

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
W
WITHDRAWN: Detection and impact of hypoxic regions in multicellular tumor spheroid cultures formed by head and neck squamous cell carcinoma cells lines.
David A Close, Paul A Johnston

SLAS Discov· December 2023

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
C
Characterization of allosteric modulators that disrupt androgen receptor co-activator protein-protein interactions to alter transactivation-Drug leads for metastatic castration resistant prostate cancer.
Ashley T Fancher, Yun Hua, David A Close, Wei Xu, Lee A McDermott

SLAS Discov· October 2023

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
D
Detection and impact of hypoxic regions in multicellular tumor spheroid cultures formed by head and neck squamous cell carcinoma cells lines.
David A Close, Paul A Johnston

SLAS Discov· January 2022

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
U
Unbiased High-Throughput Drug Combination Pilot Screening Identifies Synergistic Drug Combinations Effective against Patient-Derived and Drug-Resistant Melanoma Cell Lines.
David A Close, John M Kirkwood, Ronald J Fecek, Walter J Storkus, Paul A Johnston

SLAS Discov· June 2021

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
S
Selecting a minimal set of androgen receptor assays for screening chemicals.
Richard Judson, Keith Houck, Katie Paul Friedman, Jason Brown, Patience Browne, David A Close

Regul Toxicol Pharmacol· November 2020

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
M
Maximizing the Value of Cancer Drug Screening in Multicellular Tumor Spheroid Cultures: A Case Study in Five Head and Neck Squamous Cell Carcinoma Cell Lines.
Stanton J Kochanek, David A Close, Daniel P Camarco, Paul A Johnston

SLAS Discov· April 2020

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
H
High-Content Screening Campaign to Identify Compounds That Inhibit or Disrupt Androgen Receptor-Transcriptional Intermediary Factor 2 Protein-Protein Interactions for the Treatment of Prostate Cancer.
Ashley T Fancher, Yun Hua, Daniel P Camarco, David A Close, Christopher J Strock

Assay Drug Dev Technol· October 2019

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
C
Confirmation of Selected Synergistic Cancer Drug Combinations Identified in an HTS Campaign and Exploration of Drug Efflux Transporter Contributions to the Mode of Synergy.
Stanton J Kochanek, David A Close, Allen Xinwei Wang, Tongying Shun, Philip E Empey

SLAS Discov· July 2019

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
I
Implementation of the NCI-60 Human Tumor Cell Line Panel to Screen 2260 Cancer Drug Combinations to Generate >3 Million Data Points Used to Populate a Large Matrix of Anti-Neoplastic Agent Combinations (ALMANAC) Database.
David A Close, Allen Xinwei Wang, Stanton J Kochanek, Tongying Shun, Julie L Eiseman

SLAS Discov· March 2019

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
H
High Content Screening Characterization of Head and Neck Squamous Cell Carcinoma Multicellular Tumor Spheroid Cultures Generated in 384-Well Ultra-Low Attachment Plates to Screen for Better Cancer Drug Leads.
Stanton J Kochanek, David A Close, Paul A Johnston

Assay Drug Dev Technol· January 2019

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
T
The Generation of Three-Dimensional Head and Neck Cancer Models for Drug Discovery in 384-Well Ultra-Low Attachment Microplates.
David A Close, Daniel P Camarco, Feng Shan, Stanton J Kochanek, Paul A Johnston

Methods Mol Biol· June 2018

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
H
High-Content Screening Comparison of Cancer Drug Accumulation and Distribution in Two-Dimensional and Three-Dimensional Culture Models of Head and Neck Cancer.
Feng Shan, David A Close, Daniel P Camarco, Paul A Johnston

Assay Drug Dev Technol· January 2018

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
M
Mechanism of action of selective inhibitors of IL-6 induced STAT3 pathway in head and neck cancer cell lines.
Malabika Sen, Paul A Johnston, Netanya I Pollock, Kara DeGrave, Sonali C Joyce, David A Close

J Chem Biol· July 2017

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
R
Reconfiguring the AR-TIF2 Protein-Protein Interaction HCS Assay in Prostate Cancer Cells and Characterizing the Hits from a LOPAC Screen.
Ashley T Fancher, Yun Hua, Daniel P Camarco, David A Close, Christopher J Strock

Assay Drug Dev Technol· October 2016

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
P
Projected Scenarios for Coastal First Nations' Fisheries Catch Potential under Climate Change: Management Challenges and Opportunities.
Lauren V Weatherdon, Yoshitaka Ota, Miranda C Jones, David A Close, William W L Cheung

PLoS One· July 2016

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
P
Production of Uniform 3D Microtumors in Hydrogel Microwell Arrays for Measurement of Viability, Morphology, and Signaling Pathway Activation.
Manjulata Singh, David A Close, Shilpaa Mukundan, Paul A Johnston, Shilpa Sant

Assay Drug Dev Technol· November 2015

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
A
A putative corticosteroid hormone in Pacific lamprey, Entosphenus tridentatus.
Satbir Rai, András Szeitz, Brent W Roberts, Quill Christie, Wesley Didier, David A Close

Gen Comp Endocrinol· February 2015

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
S
Steroid profiling reveals widespread local regulation of glucocorticoid levels during mouse development.
Matthew D Taves, Adam W Plumb, Benjamin A Sandkam, Chunqi Ma, Jessica Grace Van Der Gugten, David A Close

Endocrinology· February 2015

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
R
Regulation of a putative corticosteroid, 17,21-dihydroxypregn-4-ene,3,20-one, in sea lamprey, Petromyzon marinus.
Brent W Roberts, Wes Didier, Satbir Rai, Nicholas S Johnson, Scot Libants, David A Close

Gen Comp Endocrinol· January 2014

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
P
Population genomics of Pacific lamprey: adaptive variation in a highly dispersive species.
Jon E Hess, Nathan R Campbell, David A Close, Margaret F Docker, Shawn R Narum

Mol Ecol· June 2013

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
1
11-deoxycortisol is a corticosteroid hormone in the lamprey.
David A Close, Sang-Seon Yun, Stephen D McCormick, Andrew J Wildbill, Weiming Li

Proc Natl Acad Sci U S A· August 2010

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis