Publications by authors named "David A Colby"

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Stability studies of β-Amino- and β-Hydroxy difluoromethyl ketones in rat serum and rat liver microsomes.
Baharul Islam, Katherine E Kreusel, Suresh P Sulochana, Alex L Nguyen, Munia F Sowaileh, David A Colby

Bioorg Med Chem Lett· November 2024

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Synthesis of α,α-Difluoro-β-amino Ketones from -Boc-α-Amidosulfones and Pentafluoro--diols.
Baharul Islam, Suresh P Sulochana, David A Colby

J Org Chem· May 2024

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Transient Formation of Hemiketals from Pentafluoro--diols in the Presence of Alcohols.
Baharul Islam, David A Colby

J Fluor Chem· August 2023

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Comparison of Conformational Analyses of Naturally Occurring Flavonoid--Glycosides with Unnatural Flavonoid-CF-Glycosides Using Molecular Modeling.
Reem A Alkhodier, Sushil K Mishra, Robert J Doerksen, David A Colby

J Chem Inf Model· January 2023

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Generation of formaldehyde and formaldehyde-d for hydroxymethylations and hydroxydeuteromethylations of difluoroenolates and difluorobenzyl carbanions.
Hari R Khatri, Changho Han, Reem A Alkhodier, Amna T Adam, Baharul Islam, David A Colby

Chem Commun (Camb)· May 2022

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Synthesis of Difluorinated Halohydrins by the Chemoselective Addition of Difluoroenolates to α-Haloketones.
Munia F Sowaileh, Maali D Alshammari, David A Colby

Org Lett· July 2021

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Synthesis, biological evaluation, and NMR studies of 3-fluorinated derivatives of 3',4',5'-trihydroxyflavone and 3',4',5'-trimethoxyflavone.
Maali D Alshammari, Pavel V Kucheryavy, Nicole M Ashpole, David A Colby

Bioorg Med Chem Lett· January 2021

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Synthesis of β-Fluoro-α,β-Unsaturated Amides from the Fragmentation of Morpholine 3,3,3-Trifluoropropanamide by Grignard Reagents.
Amna T Adam, Frank R Fronczek, David A Colby

Org Lett· April 2020

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Controlling the Cleavage of Carbon-Carbon Bonds To Generate α,α-Difluorobenzyl Carbanions for the Construction of Difluoromethylbenzenes.
Hari R Khatri, Changho Han, Erica Luong, Xiaoliang Pan, Amna T Adam, David A Colby

J Org Chem· September 2019

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Agonists of the γ-aminobutyric acid type B (GABA) receptor derived from β-hydroxy and β-amino difluoromethyl ketones.
Munia F Sowaileh, Amy E Salyer, Kuldeep K Roy, Jinu P John, James R Woods, David A Colby

Bioorg Med Chem Lett· September 2018

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Energy Drinks: Implications for the Breastfeeding Mother.
Janet Thorlton, Azza Ahmed, David A Colby

MCN Am J Matern Child Nurs· March 2018

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Magnesium-Promoted Additions of Difluoroenolates to Unactivated Imines.
Alex L Nguyen, Hari R Khatri, James R Woods, Cassidy S Baldwin, Frank R Fronczek, David A Colby

J Org Chem· March 2018

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Energy Drink Adverse Effects: What Is Being Done to Protect Public Health?
Janet Thorlton, David A Colby

West J Nurs Res· January 2018

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Application of the Pentafluorosulfanyl Group as a Bioisosteric Replacement.
Munia F Sowaileh, Robert A Hazlitt, David A Colby

ChemMedChem· September 2017

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Generation of Magnesium Pentafluoropropen-2-olate from Hexafluoroisopropanol and Synthesis of 2,2,4,4,4-Pentafluoro-3,3-dihydroxyketones.
Robert A Hazlitt, Que-Lynn Tran, Munia F Sowaileh, David A Colby

J Org Chem· February 2017

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Conversion of Methyl Ketones and Methyl Sulfones into α-Deutero-α,α-Difluoromethyl Ketones and α-Deutero-α,α-Difluoromethyl Sulfones in Three Synthetic Steps.
Munia F Sowaileh, Changho Han, Robert A Hazlitt, Eun Hoo Kim, Jinu P John, David A Colby

Tetrahedron Lett· February 2017

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15-Methylene-Eburnamonine Kills Leukemic Stem Cells and Reduces Engraftment in a Humanized Bone Marrow Xenograft Mouse Model of Leukemia.
Dilini C Gunasekara, Mary M Zheng, Tara Mojtahed, James R Woods, Tamer E Fandy, David A Colby

ChemMedChem· November 2016

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Optimized Synthesis of a Pentafluoro--diol and Conversion to a -Glucopyranose through Trifluoroacetate-Release and Halogenation.
Robert A Hazlitt, Jinu P John, Que-Lynn Tran, David A Colby

Tetrahedron Lett· April 2016

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In vitro characterization of transport and metabolism of the alkaloids: vincamine, vinpocetine and eburnamonine.
Tamer E Fandy, Inas Abdallah, Maan Khayat, David A Colby, Hazem E Hassan

Cancer Chemother Pharmacol· February 2016

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Activation of the γ-Aminobutyric Acid Type B (GABA(B)) Receptor by Agonists and Positive Allosteric Modulators.
Katie M Brown, Kuldeep K Roy, Gregory H Hockerman, Robert J Doerksen, David A Colby

J Med Chem· August 2015

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A small molecule screen identifies a novel compound that induces a homeotic transformation in Hydra.
Kristine M Glauber, Catherine E Dana, Steve S Park, David A Colby, Yukihiko Noro

Development· June 2015

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Effect of Substituents and Stability of Transient Aluminum-Aminals in the Presence of Nucleophiles.
Francis J Barrios, Brannon C Springer, Robert A Hazlitt, David A Colby

Synthesis (Stuttg)· January 2015

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Proposed actions for the US Food and Drug Administration to implement to minimize adverse effects associated with energy drink consumption.
Janet Thorlton, David A Colby, Paige Devine

Am J Public Health· July 2014

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A small molecule screen identifies a novel compound that induces a homeotic transformation in Hydra.
Kristine M Glauber, Catherine E Dana, Steve S Park, David A Colby, Yukihiko Noro

Development· December 2013

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Synthesis of 15-methylene-eburnamonine from (+)-vincamine, evaluation of anticancer activity, and investigation of mechanism of action by quantitative NMR.
James R Woods, Mark V Riofski, Mary M Zheng, Melissa A O'Banion, Huaping Mo, David A Colby

Bioorg Med Chem Lett· November 2013

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