Publications by authors named "David A Collier"

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Anxiety-like behavior and altered hippocampal activity in a transgenic mouse model of Fabry disease.
Kai Kummer, Jeiny Luna Choconta, Marie-Luise Edenhofer, Archana Bajpai, Gopuraja Dharmalingam, David A Collier

Neurobiol Dis· February 2025

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Longitudinal changes in DNA methylation associated with clozapine use in treatment-resistant schizophrenia from two international cohorts.
Amy L Gillespie, Emma M Walker, Eilis Hannon, Grant A McQueen, Kyra-Verena Sendt, David A Collier

Transl Psychiatry· September 2024

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MAVEN: compound mechanism of action analysis and visualisation using transcriptomics and compound structure data in R/Shiny.
Layla Hosseini-Gerami, Rosa Hernansaiz Ballesteros, Anika Liu, Howard Broughton, David Andrew Collier

BMC Bioinformatics· September 2023

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Galectin-3 activates spinal microglia to induce inflammatory nociception in wild type but not in mice modelling Alzheimer's disease.
George Sideris-Lampretsas, Silvia Oggero, Lynda Zeboudj, Rita Silva, Archana Bajpai, David A Collier

Nat Commun· June 2023

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Benchmarking causal reasoning algorithms for gene expression-based compound mechanism of action analysis.
Layla Hosseini-Gerami, Ixavier Alonzo Higgins, David A Collier, Emma Laing, David Evans

BMC Bioinformatics· April 2023

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Mechanism of action deconvolution of the small-molecule pathological tau aggregation inhibitor Anle138b.
Layla Hosseini-Gerami, Elena Ficulle, Neil Humphryes-Kirilov, David C Airey, James Scherschel, David A Collier

Alzheimers Res Ther· March 2023

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The Role of miRNAs in Neuropathic Pain.
Martina Morchio, Emanuele Sher, David A Collier, Daniel W Lambert, Fiona M Boissonade

Biomedicines· March 2023

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Mapping genomic loci implicates genes and synaptic biology in schizophrenia.
Vassily Trubetskoy, Antonio F Pardiñas, Ting Qi, Georgia Panagiotaropoulou, Swapnil Awasthi, David A Collier

Nature· April 2022

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Bridging of childhood obsessive-compulsive personality disorder traits and adult eating disorder symptoms: A network analysis approach.
Sarah Giles, Elizabeth K Hughes, Matthew Fuller-Tyszkiewicz, Janet Treasure, Fernando Fernandez-Aranda, David A Collier

Eur Eat Disord Rev· March 2022

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A human tau seeded neuronal cell model recapitulates molecular responses associated with Alzheimer's disease.
Elena Ficulle, Sarubini Kananathan, David Airey, Severine I Gharbi, Neil Humphryes-Kirilov, David A Collier

Sci Rep· February 2022

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Full-length transcript sequencing of human and mouse cerebral cortex identifies widespread isoform diversity and alternative splicing.
Szi Kay Leung, Aaron R Jeffries, Isabel Castanho, Ben T Jordan, Karen Moore, David A Collier

Cell Rep· November 2021

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Genetic underpinnings of sociability in the general population.
Janita Bralten, Nina R Mota, Cornelius J H M Klemann, Ward De Witte, Emma Laing, David A Collier

Neuropsychopharmacology· August 2021

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HLA-DQB1 6672G>C (rs113332494) is associated with clozapine-induced neutropenia and agranulocytosis in individuals of European ancestry.
Bettina Konte, James T R Walters, Dan Rujescu, Sophie E Legge, Antonio F Pardiñas, David A Collier

Transl Psychiatry· April 2021

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DNA methylation meta-analysis reveals cellular alterations in psychosis and markers of treatment-resistant schizophrenia.
Eilis Hannon, Emma L Dempster, Georgina Mansell, Joe Burrage, Nick Bass, David Andrew Collier

Elife· February 2021

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Whole transcriptome in silico screening implicates cardiovascular and infectious disease in the mechanism of action underlying atypical antipsychotic side effects.
Yasaman Malekizadeh, Gareth Williams, Mark Kelson, David Whitfield, Jonathan Mill, David A Collier

Alzheimers Dement (N Y)· August 2020

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Meta-Analysis of the Alzheimer's Disease Human Brain Transcriptome and Functional Dissection in Mouse Models.
Ying-Wooi Wan, Rami Al-Ouran, Carl G Mangleburg, Thanneer M Perumal, Tom V Lee, David A Collier

Cell Rep· July 2020

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Transcriptional Signatures of Tau and Amyloid Neuropathology.
Isabel Castanho, Tracey K Murray, Eilis Hannon, Aaron Jeffries, Emma Walker, David A Collier

Cell Rep· February 2020

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TractaViewer: a genome-wide tool for preliminary assessment of therapeutic target druggability.
Neil Pearson, Karim Malki, David Evans, Lewis Vidler, Cara Ruble, David A Collier

Bioinformatics· November 2019

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Publisher Correction: Common schizophrenia alleles are enriched in mutation-intolerant genes and in regions under strong background selection.
Antonio F Pardiñas, Peter Holmans, Andrew J Pocklington, Valentina Escott-Price, Stephan Ripke, David A Collier

Nat Genet· July 2019

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A genome-wide association study in individuals of African ancestry reveals the importance of the Duffy-null genotype in the assessment of clozapine-related neutropenia.
Sophie E Legge, Antonio F Pardiñas, Marinka Helthuis, John A Jansen, Karel Jollie, David A Collier

Mol Psychiatry· March 2019

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Associations between childhood maltreatment and inflammatory markers.
Alish B Palmos, Stuart Watson, Tom Hughes, Andreas Finkelmeyer, R Hamish McAllister-Williams, David A Collier

BJPsych Open· January 2019

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Genome-wide RNAseq study of the molecular mechanisms underlying microglia activation in response to pathological tau perturbation in the rTg4510 tau transgenic animal model.
Hong Wang, Yupeng Li, John W Ryder, Justin T Hole, Philip J Ebert, David A Collier

Mol Neurodegener· December 2018

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Author Correction: Expression-based drug screening of neural progenitor cells from individuals with schizophrenia.
Benjamin Readhead, Brigham J Hartley, Brian J Eastwood, David A Collier, David Evans

Nat Commun· November 2018

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Expression-based drug screening of neural progenitor cells from individuals with schizophrenia.
Benjamin Readhead, Brigham J Hartley, Brian J Eastwood, David A Collier, David Evans

Nat Commun· October 2018

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Loss of Trem2 in microglia leads to widespread disruption of cell coexpression networks in mouse brain.
Guillermo Carbajosa, Karim Malki, Nathan Lawless, Hong Wang, John W Ryder, David A Collier

Neurobiol Aging· September 2018

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