Publications by authors named "David A Cooper"

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Cryopreservation of siRNA-Treated Cells Is Feasible.
Melanie Sauer, Xavier Segarra-Visent, Leon Breuer, Vasileios Tzirtziganis, Tatyana Ryaykenen, David A Cooper

Nucleic Acid Ther· December 2025

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Optimized chemical structure extends silencing duration of therapeutic siRNAs in dividing cancer and immune cells.
Anastasia Kremer, Tatyana Ryaykenen, Xavier Segarra-Visent, Melanie Sauer, Leon Breuer, David A Cooper

Mol Ther· November 2025

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Intracellular Pocket Conformations Determine Signaling Efficacy through the μ Opioid Receptor.
David A Cooper, Joseph DePaolo-Boisvert, Stanley A Nicholson, Barien Gad, David D L Minh

J Chem Inf Model· February 2025

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Ligand Reorganization for End-Point Binding Free Energy Calculations: Identifying Preferred Poses of Fentanyls in the μ Opioid Receptor.
David D L Minh, David A Cooper, Bing Xie, Lei Shi

J Chem Theory Comput· January 2025

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Intracellular pocket conformations determine signaling efficacy through the opioid receptor.
David A Cooper, Joseph DePaolo-Boisvert, Stanley A Nicholson, Barien Gad, David D L Minh

bioRxiv· December 2024

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Dendritic amphiphilic siRNA: Selective albumin binding, efficacy, and low toxicity.
Hassan H Fakih, Qi Tang, Ashley Summers, Minwook Shin, Julianna E Buchwald, David A Cooper

Mol Ther Nucleic Acids· December 2023

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Rational design of a JAK1-selective siRNA inhibitor for the modulation of autoimmunity in the skin.
Qi Tang, Hassan H Fakih, Mohammad Zain Ui Abideen, Samuel R Hildebrand, Khashayar Afshari, David A Cooper

Nat Commun· November 2023

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Divalent siRNAs are bioavailable in the lung and efficiently block SARS-CoV-2 infection.
Vignesh N Hariharan, Minwook Shin, Ching-Wen Chang, Daniel O'Reilly, Annabelle Biscans, David A Cooper

Proc Natl Acad Sci U S A· March 2023

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Engineered ionizable lipid siRNA conjugates enhance endosomal escape but induce toxicity in vivo.
Annabelle Biscans, Socheata Ly, Nicholas McHugh, David A Cooper, Anastasia Khvorova

J Control Release· September 2022

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RNAi-based modulation of IFN-γ signaling in skin.
Qi Tang, Jacquelyn Sousa, Dimas Echeverria, Xueli Fan, Ying-Chao Hsueh, David A Cooper

Mol Ther· August 2022

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Broadly neutralizing antibody responses in the longitudinal primary HIV-1 infection Short Pulse Anti-Retroviral Therapy at Seroconversion cohort.
Luke A Granger, Isabella Huettner, Franka Debeljak, Pontiano Kaleebu, Mauro Schechter, David A Cooper

AIDS· November 2021

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Comorbidity Medications Are Dispensed to More People Receiving Antiretroviral Therapy for HIV Compared with the General Population in Australia.
Nila J Dharan, Tomas Radovich, Samuel Che, Kathy Petoumenos, Prabhjot Juneja, David A Cooper

AIDS Res Hum Retroviruses· April 2020

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The Influence of HIV Status on the Burden and Clinical Manifestations of Gastrointestinal Pathogens in Yangon, Myanmar.
Win Pa Pa Aung, Nan Phyu Sin Toe Myint, Thet Tun Zaw, David A Cooper, Ne Myo Aung

Am J Trop Med Hyg· April 2020

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Possible clearance of transfusion-acquired /LTR-deleted attenuated HIV-1 infection by an elite controller with CCR5 Δ32 heterozygous and HLA-B57 genotype.
John Zaunders, Wayne B Dyer, Melissa Churchill, C Mee Ling Munier, Philip H Cunningham, David A Cooper

J Virus Erad· April 2019

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Implications of Image-Defined Risk Factors and Primary-Site Response on Local Control and Radiation Treatment Delivery in the Management of High-Risk Neuroblastoma: Is There a Role for De-escalation of Adjuvant Primary-Site Radiation Therapy?
John T Lucas, M Beth McCarville, David A Cooper, Mikhail Doubrovin, Daniel Wakefield

Int J Radiat Oncol Biol Phys· March 2019

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HIV-1 DNA Is Maintained in Antigen-Specific CD4+ T Cell Subsets in Patients on Long-Term Antiretroviral Therapy Regardless of Recurrent Antigen Exposure.
William J Hey-Nguyen, Michelle Bailey, Yin Xu, Kazuo Suzuki, David Van Bockel, David A Cooper

AIDS Res Hum Retroviruses· January 2019

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HIV treatment regimens and adherence to national guidelines in Australia: an analysis of dispensing data from the Australian pharmaceutical benefits scheme.
Nila J Dharan, Tomas Radovich, Samuel Che, Kathy Petoumenos, Prabhjot Juneja, David A Cooper

BMC Public Health· January 2019

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Early Treatment of Primary HIV Infection Is Associated with Decreased Mortality.
Angie N Pinto, Pat Grey, Ansari Shaik, David A Cooper, Anthony D Kelleher

AIDS Res Hum Retroviruses· November 2018

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Population-level effectiveness of rapid, targeted, high-coverage roll-out of HIV pre-exposure prophylaxis in men who have sex with men: the EPIC-NSW prospective cohort study.
Andrew E Grulich, Rebecca Guy, Janaki Amin, Fengyi Jin, Christine Selvey, Craig Cooper, David A Cooper

Lancet HIV· November 2018

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The cascade of HIV care among key populations in Indonesia: a prospective cohort study.
Pande Putu Januraga, Joanne Reekie, Tri Mulyani, Bony Wiem Lestari, Shelly Iskandar, David A Cooper

Lancet HIV· October 2018

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National characteristics and trends in antiretroviral treatment in Australia can be accurately estimated using a large clinical cohort.
Robin Huang, Kathy Petoumenos, Richard T Gray, Hamish McManus, Nila Dharan, David A Cooper

J Clin Epidemiol· August 2018

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The 2016 HIV diagnosis and care cascade in New South Wales, Australia: meeting the UNAIDS 90-90-90 targets.
Phillip Keen, Richard T Gray, Barbara Telfer, Rebecca Guy, Heather-Marie Schmidt, David A Cooper

J Int AIDS Soc· April 2018

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Correction: expanded HIV pre-exposure prophylaxis (PrEP) implementation in communities in new South Wales, Australia (EPIC-NSW): design of an open label, single arm implementation trial.
Iryna B Zablotska, Christine Selvey, Rebecca Guy, Karen Price, Jo Holden, David A Cooper

BMC Public Health· February 2018

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