Publications by authors named "David A Davis"

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Caspase cleavage of Kaposi sarcoma-associated herpesvirus proteins: a role for K5 in preventing caspase-mediated cell death during lytic replication.
David A Davis, Yana Astter, Emma N Treco, Prabha Shrestha, Alexandra Stream

J Virol· September 2025

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Alzheimer's disease signatures in the brain transcriptome of Estuarine Dolphins.
Wendy Noke Durden, Megan K Stolen, Susanna P Garamszegi, Sandra Anne Banack, Daniel J Brzostowicki, David A Davis

Commun Biol· September 2025

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Novel Cereblon-Binding Immunomodulators Have Increased Potency Against Gammaherpesvirus- Associated Lymphomas In Vitro.
Prabha Shrestha, Emma N Treco, David A Davis, Robert Yarchoan

J Med Virol· August 2025

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Exploring potential mechanisms of an African protective locus for Alzheimer's disease in APOEε4 carriers.
Luciana Bertholim-Nasciben, Karen Nuytemans, Derek Van Booven, Farid Rajabli, Sofia Moura, David A Davis

Alzheimers Dement· July 2025

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A Transcriptomic Roadmap of Parkinson's Disease Progression at Single Cell Resolution.
Tereza Clarence, Nicolas Masse, Christian Porras, Prashant Nm, Sabina Berretta, David A Davis

medRxiv· July 2025

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Caspase Cleavage of Kaposi Sarcoma-Associated Herpesvirus Proteins: A role for K5 in Preventing Caspase-Mediated Cell Death during Lytic Replication.
Yana Astter, David A Davis, Emma Treco, Prabha Shrestha, Alexandra Stream

bioRxiv· April 2025

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The elevated expression of ORF75, a KSHV lytic gene, in Kaposi sarcoma lesions is driven by a GC-rich DNA cis element in its promoter region.
Ashwin Nair, David A Davis, Andrew Warner, Baktiar Karim, Ramya Ramaswami

PLoS Pathog· March 2025

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A multi-regional human brain atlas of chromatin accessibility and gene expression facilitates promoter-isoform resolution genetic fine-mapping.
Pengfei Dong, Liting Song, Jaroslav Bendl, Ruth Misir, Zhiping Shao, David A Davis

Nat Commun· November 2024

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A multi-region single nucleus transcriptomic atlas of Parkinson's disease.
Prashant N M, John F Fullard, Tereza Clarence, Deepika Mathur, Clara Casey, David A Davis

Sci Data· November 2024

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Inflammasome activation in patients with Kaposi sarcoma herpesvirus-associated diseases.
Silvia Lucena Lage, Ramya Ramaswami, Joseph M Rocco, Adam Rupert, David A Davis

Blood· October 2024

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Targeting hypoxia-inducible factors in malignancies caused by Kaposis sarcoma associated herpesvirus.
David A Davis, Prabha Shrestha, Robert Yarchoan

Glob Health Med· October 2024

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African origin haplotype protective for Alzheimer's disease in ε4 carriers: exploring potential mechanisms.
Luciana Bertholim-Nasciben, Karen Nuytemans, Derek Van Booven, Farid Rajabli, Sofia Moura, David A Davis

bioRxiv· October 2024

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Discovery of a nasal spray steroid, tixocortol, as an inhibitor of SARS-CoV-2 main protease and viral replication.
David A Davis, Ashwin Nair, Yana Astter, Emma Treco, Brian Peyser

RSC Med Chem· September 2024

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The Elevated Expression of ORF75, a Lytic KSHV Gene, in Kaposi Sarcoma Lesions is Driven by a GC-rich DNA cis Element in its Promoter Region.
Ashwin Nair, David A Davis, Andrew Warner, Baktiar Karim, Ramya Ramaswami

bioRxiv· September 2024

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Selective vulnerability of layer 5a corticostriatal neurons in Huntington's disease.
Christina Pressl, Kert Mätlik, Laura Kus, Paul Darnell, Ji-Dung Luo, David A Davis

Neuron· March 2024

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Cell-type-specific CAG repeat expansions and toxicity of mutant Huntingtin in human striatum and cerebellum.
Kert Mätlik, Matthew Baffuto, Laura Kus, Amit Laxmikant Deshmukh, David A Davis

Nat Genet· March 2024

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Corpora amylacea negatively correlate with hippocampal tau pathology in Alzheimer's disease.
Julian D Dallmeier, Ryan Gober, Regina T Vontell, Ayled Barreda, Daniel A Dorfsman, David A Davis

Front Neurosci· February 2024

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Molecular profiling of human substantia nigra identifies diverse neuron types associated with vulnerability in Parkinson's disease.
Qian Wang, Minghui Wang, Insup Choi, Lily Sarrafha, Marianna Liang, David A Davis

Sci Adv· January 2024

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TDP-43 and Alzheimer's Disease Pathology in the Brain of a Harbor Porpoise Exposed to the Cyanobacterial Toxin BMAA.
Susanna P Garamszegi, Daniel J Brzostowicki, Thomas M Coyne, Regina T Vontell, David A Davis

Toxins (Basel)· January 2024

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Association of region-specific hippocampal reduction of neurogranin with inflammasome proteins in brains of Alzheimer's disease.
Regina T Vontell, Ryan Gober, Julian Dallmeier, Daniel Brzostowicki, Ayled Barreda, David A Davis

Alzheimers Dement (N Y)· January 2024

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Selective Vulnerability of Layer 5a Corticostriatal Neurons in Huntington's Disease.
Christina Pressl, Kert Mätlik, Laura Kus, Paul Darnell, Ji-Dung Luo, David A Davis

bioRxiv· October 2023

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Hypoxia and hypoxia-inducible factors in Kaposi sarcoma-associated herpesvirus infection and disease pathogenesis.
David A Davis, Prabha Shrestha, Robert Yarchoan

J Med Virol· September 2023

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GRL-142 binds to and impairs HIV-1 integrase nuclear localization signal and potently suppresses highly INSTI-resistant HIV-1 variants.
Manabu Aoki, Hiromi Aoki-Ogata, Haydar Bulut, Hironori Hayashi, Nobutoki Takamune, David A Davis

Sci Adv· July 2023

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Mechanism and therapeutic implications of pomalidomide-induced immune surface marker upregulation in EBV-positive lymphomas.
Hannah K Jaeger, David A Davis, Ashwin Nair, Prabha Shrestha, Alexandra Stream

Sci Rep· July 2023

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Cell Type Specific CAG Repeat Expansions and Toxicity of Mutant Huntingtin in Human Striatum and Cerebellum.
Kert Mätlik, Matthew Baffuto, Laura Kus, Amit Laxmikant Deshmukh, David A Davis

bioRxiv· June 2023

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