Publications by authors named "David A Dean"

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Subnuclear organization and mislocalization of plasmids reduce transgene expression.
Ningyang Gu, Uday K Baliga, Joseph J Porter, John D Lueck, David A Dean

Mol Ther Nucleic Acids· December 2025

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Anticodon Edited Transfer RNAs (ACE-tRNAs) Encoded as Therapeutic Nonviral Minimal DNA Vectors.
Joseph J Porter, Wooree Ko, Emily G Sorensen, Zachary Cheung, Tyler Couch, David A Dean

bioRxiv· September 2025

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Ki-67 promotes inflammatory signaling governing neutrophil recruitment during respiratory infections.
Min Yee, Ravi Misra, Sarah Vesecky, Michael Barravecchia, Rauf A Najar, David A Dean

EMBO Mol Med· August 2025

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Electroporation- and Liposome-Mediated Co-Transfection of Single and Multiple Plasmids.
Uday K Baliga, Anthony Gurunian, Aitor Nogales, Luis Martinez-Sobrido, David A Dean

Pharmaceutics· July 2025

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MTOR maintains endothelial cell integrity to limit lung vascular injury.
Michelle Warren Millar, Rauf A Najar, Spencer A Slavin, Mohammad Shadab, Imran Tahir, David A Dean

J Biol Chem· December 2024

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Occludin Is Essential to Maintain Normal Alveolar Barrier Integrity and Its Protective Role During ARDS Progression.
Xin Lin, Haiqing Bai, Michael Barravecchia, Rosemary Norman, Gillian M Schiralli Lester, David A Dean

Int J Mol Sci· October 2024

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Impact of Peptide Sequence on Functional siRNA Delivery and Gene Knockdown with Cyclic Amphipathic Peptide Delivery Agents.
Melissa L Jagrosse, Uday K Baliga, Christopher W Jones, Jade J Russell, Claudia I García, David A Dean

Mol Pharm· December 2023

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Spleen Tyrosine Kinase phosphorylates VE-cadherin to cause endothelial barrier disruption in acute lung injury.
Mohammad Shadab, Spencer A Slavin, Zahra Mahamed, Michelle W Millar, Rauf A Najar, David A Dean

J Biol Chem· December 2023

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Multiple conductance states of lipid pores during Voltage-Clamp electroporation.
Anthony Gurunian, David A Dean

Bioelectrochemistry· June 2023

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Upregulation of alveolar fluid clearance is not sufficient for Na,K-ATPase β subunit-mediated gene therapy of LPS-induced acute lung injury in mice.
Jing Liu, Gillian M Schiralli-Lester, Rosemary Norman, David A Dean

Sci Rep· April 2023

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Modeling and simulation of current-clamp electroporation.
Anthony Gurunian, David A Dean

Bioelectrochemistry· October 2022

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Gene Therapy for Acute Respiratory Distress Syndrome.
Jing Liu, David A Dean

Front Physiol· January 2022

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Gene transfer of MRCKα rescues lipopolysaccharide-induced acute lung injury by restoring alveolar capillary barrier function.
Jing Liu, David A Dean

Sci Rep· October 2021

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Synthesis and Application of Peptide-siRNA Nanoparticles from Disulfide-Constrained Cyclic Amphipathic Peptides for the Functional Delivery of Therapeutic Oligonucleotides to the Lung.
Jade J Welch, David A Dean, Bradley L Nilsson

Methods Mol Biol· March 2021

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Pulmonary gene delivery-Realities and possibilities.
Uday K Baliga, David A Dean

Exp Biol Med (Maywood)· February 2021

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The Na+, K+-ATPase β1 subunit regulates epithelial tight junctions via MRCKα.
Haiqing Bai, Rui Zhou, Michael Barravecchia, Rosemary Norman, Alan Friedman, David A Dean

JCI Insight· February 2021

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Changes in lung immune cell infiltrates after electric field treatment in mice.
Sophia I Eliseeva, Zackery A Knowlden, Gillian MSchiralli Lester, David A Dean, Steve N Georas

Sci Rep· January 2021

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Disruption of normal patterns of FOXF1 expression in a lethal disorder of lung development.
Laurie A Steiner, Michael Getman, Gillian M Schiralli Lester, M Anwar Iqbal, Philip Katzman, David A Dean

J Med Genet· May 2020

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In vivo rescue of recombinant Zika virus from an infectious cDNA clone and its implications in vaccine development.
Gines Ávila-Pérez, Aitor Nogales, Jun-Gyu Park, Desarey Morales Vasquez, David A Dean

Sci Rep· January 2020

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RNAi therapeutic strategies for acute respiratory distress syndrome.
Melissa L Jagrosse, David A Dean, Arshad Rahman, Bradley L Nilsson

Transl Res· December 2019

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Caveolin-1 gene therapy inhibits inflammasome activation to protect from bleomycin-induced pulmonary fibrosis.
Xin Lin, Michael Barravecchia, R Matthew Kottmann, Patricia Sime, David A Dean

Sci Rep· December 2019

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Critical role of autophagy regulator Beclin1 in endothelial cell inflammation and barrier disruption.
Antony Leonard, Michelle Warren Millar, Spencer A Slavin, Kaiser M Bijli, Dawling A Dionisio Santos, David A Dean

Cell Signal· September 2019

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Building and Breaking the Cell Wall in Four Acts: A Kinesthetic and Tactile Role-Playing Exercise for Teaching Beta-Lactam Antibiotic Mechanism of Action and Resistance.
John Popovich, Michelle Stephens, Holly Celaya, Serena Suwarno, Shizuka Barclay, David A Dean

J Microbiol Biol Educ· January 2018

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Cytoplasmic transport and nuclear import of plasmid DNA.
Haiqing Bai, Gillian M Schiralli Lester, Laura C Petishnok, David A Dean

Biosci Rep· December 2017

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Featured Article: Electroporation-mediated gene delivery of surfactant protein B (SP-B) restores expression and improves survival in mouse model of SP-B deficiency.
Rebecca C Barnett, Xin Lin, Michael Barravecchia, Rosemary A Norman, Karen L de Mesy Bentley, David A Dean

Exp Biol Med (Maywood)· July 2017

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