Publications by authors named "David A Goukassian"

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Long-term Pathway Activation in Cardiac Ventricular Tissues after Gamma and simGCRsim Irradiation.
Gisane Khachatryan, Tamara Sirunyan, Siras Hakobyan, Suren Davitavyan, Roksana Zakharyan, David A Goukassian

Radiat Res· November 2025

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The effects of space radiation on the transcriptome of heart right ventricle tissue.
Roksana Zakharyan, Siras Hakobyan, Agnieszka Brojakowska, Malik Bisserier, Shihong Zhang, David A Goukassian

NPJ Microgravity· July 2025

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Long-lasting sex-specific alteration in left ventricular cardiac transcriptome following gamma and simGCRsim radiation.
Roksana Zakharyan, Siras Hakobyan, Agnieszka Brojakowska, Suren Davitavyan, Ani Stepanyan, David A Goukassian

Sci Rep· February 2025

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Evaluating sex-specific responses to western diet across the lifespan: impact on cardiac function and transcriptomic signatures in C57BL/6J mice at 530 and 640/750 days of age.
Ani Stepanyan, Agnieszka Brojakowska, Roksana Zakharyan, Siras Hakobyan, Suren Davitavyan, David A Goukassian

Cardiovasc Diabetol· December 2024

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Simulated Microgravity Alters Gene Regulation Linked to Immunity and Cardiovascular Disease.
Candice G T Tahimic, Sonette Steczina, Aimy Sebastian, Nicholas R Hum, Metadel Abegaz, David A Goukassian

Genes (Basel)· July 2024

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Lifetime evaluation of left ventricular structure and function in male ApoE null mice after gamma and space-type radiation exposure.
Agnieszka Brojakowska, Cedric J Jackson, Malik Bisserier, Mary K Khlgatian, Vineeta Jagana, David A Goukassian

Front Physiol· November 2023

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Lifetime Evaluation of Left Ventricular Structure and Function in Male C57BL/6J Mice after Gamma and Space-Type Radiation Exposure.
Agnieszka Brojakowska, Cedric J Jackson, Malik Bisserier, Mary K Khlgatian, Cynthia Grano, David A Goukassian

Int J Mol Sci· March 2023

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Author Correction: Retrospective analysis of somatic mutations and clonal hematopoiesis in astronauts.
Agnieszka Brojakowska, Anupreet Kour, Mark Charles Thel, Eunbee Park, Malik Bisserier, David A Goukassian

Commun Biol· October 2022

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Retrospective analysis of somatic mutations and clonal hematopoiesis in astronauts.
Agnieszka Brojakowska, Anupreet Kour, Mark Charles Thel, Eunbee Park, Malik Bisserier, David A Goukassian

Commun Biol· August 2022

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Astronauts Plasma-Derived Exosomes Induced Aberrant EZH2-Mediated H3K27me3 Epigenetic Regulation of the Vitamin D Receptor.
Malik Bisserier, Agnieszka Brojakowska, Nathaniel Saffran, Amit Kumar Rai, Brooke Lee, David A Goukassian

Front Cardiovasc Med· June 2022

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Spaceflight-Associated Changes of snoRNAs in Peripheral Blood Mononuclear Cells and Plasma Exosomes-A Pilot Study.
Amit Kumar Rai, K Shanmugha Rajan, Malik Bisserier, Agnieszka Brojakowska, Aimy Sebastian, David A Goukassian

Front Cardiovasc Med· June 2022

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Emerging Role of Exosomal Long Non-coding RNAs in Spaceflight-Associated Risks in Astronauts.
Malik Bisserier, Nathaniel Saffran, Agnieszka Brojakowska, Aimy Sebastian, Angela Clare Evans, David A Goukassian

Front Genet· January 2022

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Cell-Free Mitochondrial DNA as a Potential Biomarker for Astronauts' Health.
Malik Bisserier, Santhanam Shanmughapriya, Amit Kumar Rai, Carolina Gonzalez, Agnieszka Brojakowska, David A Goukassian

J Am Heart Assoc· November 2021

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Combination Therapy with STAT3 Inhibitor Enhances SERCA2a-Induced BMPR2 Expression and Inhibits Pulmonary Arterial Hypertension.
Malik Bisserier, Michael G Katz, Carlos Bueno-Beti, Agnieszka Brojakowska, Shihong Zhang, David A Goukassian

Int J Mol Sci· August 2021

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Comorbidities, sequelae, blood biomarkers and their associated clinical outcomes in the Mount Sinai Health System COVID-19 patients.
Agnieszka Brojakowska, Abrisham Eskandari, Malik Bisserier, Jeffrey Bander, Venkata Naga Srikanth Garikipati, David A Goukassian

PLoS One· July 2021

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Serum-Derived Small Extracellular Vesicles From Diabetic Mice Impair Angiogenic Property of Microvascular Endothelial Cells: Role of EZH2.
Zhongjian Cheng, Venkata Naga Srikanth Garikipati, May M Truongcao, Maria Cimini, Grace Huang, David A Goukassian

J Am Heart Assoc· May 2021

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Pathophysiology and pharmacological management of pulmonary and cardiovascular features of COVID-19.
Walid Hamouche, Malik Bisserier, Agnieszka Brojakowska, Abrisham Eskandari, Kenneth Fish, David A Goukassian

J Mol Cell Cardiol· April 2021

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Long-Term Effects of Very Low Dose Particle Radiation on Gene Expression in the Heart: Degenerative Disease Risks.
Venkata Naga Srikanth Garikipati, Arsen Arakelyan, Eleanor A Blakely, Polly Y Chang, May M Truongcao, David A Goukassian

Cells· February 2021

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Podoplanin neutralization improves cardiac remodeling and function after acute myocardial infarction.
Maria Cimini, Venkata Naga Srikanth Garikipati, Claudio de Lucia, Zhongjian Cheng, Chunlin Wang, David A Goukassian

JCI Insight· July 2019

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Short-Term Treatment with Esmolol Reverses Left Ventricular Hypertrophy in Adult Spontaneously Hypertensive Rats via Inhibition of Akt/NF-B and NFATc4.
Begoña Quintana-Villamandos, David A Goukassian, Sharath P Sasi, Emilio Delgado-Baeza

Biomed Res Int· September 2018

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Interleukin-10 Deficiency Impairs Reparative Properties of Bone Marrow-Derived Endothelial Progenitor Cell Exosomes.
Yujia Yue, Venkata Naga Srikanth Garikipati, Suresh Kumar Verma, David A Goukassian, Raj Kishore

Tissue Eng Part A· November 2017

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Interleukin-10 Inhibits Bone Marrow Fibroblast Progenitor Cell-Mediated Cardiac Fibrosis in Pressure-Overloaded Myocardium.
Suresh K Verma, Venkata N S Garikipati, Prasanna Krishnamurthy, Sarah M Schumacher, Laurel A Grisanti, David A Goukassian

Circulation· September 2017

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Different Sequences of Fractionated Low-Dose Proton and Single Iron-Radiation-Induced Divergent Biological Responses in the Heart.
Sharath P Sasi, Xinhua Yan, Marian Zuriaga-Herrero, Hannah Gee, Juyong Lee, David A Goukassian

Radiat Res· August 2017

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Coordinated Activation of VEGF/VEGFR-2 and PPARδ Pathways by a Multi-Component Chinese Medicine DHI Accelerated Recovery from Peripheral Arterial Disease in Type 2 Diabetic Mice.
Shuang He, Tiechan Zhao, Hao Guo, Yanzhi Meng, Gangjian Qin, David A Goukassian

PLoS One· July 2017

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Therapeutic inhibition of miR-375 attenuates post-myocardial infarction inflammatory response and left ventricular dysfunction via PDK-1-AKT signalling axis.
Venkata N S Garikipati, Suresh K Verma, Darukeshwara Jolardarashi, Zhongjian Cheng, Jessica Ibetti, David A Goukassian

Cardiovasc Res· July 2017

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