Publications by authors named "David A Harris"

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A low-protein diet drives short- and long-term improvements in metabolic health in a mouse model of sleeve gastrectomy.
Julia Illiano, Cara L Green, Alina Chao, Grace Zhu, Luiz Lopez, David A Harris

Cell Rep Med· December 2025

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Enhanced Lysosomal Activity Prevents Infection with PrP and the Seeding Activity of α-Synuclein & Tau Prions.
Robert C C Mercer, Nhat T T Le, Nadia A Mirza-Romero, Isabel C Orbe, Erin Flaherty, David A Harris

J Biol Chem· December 2025

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Tissue-Specific Effects of Dietary Protein on Cellular Senescence Are Mediated by Branched-Chain Amino Acids.
Mariah F Calubag, Ismail Ademi, Isaac D Grunow, Lucia E Breuer, Reji Babygirija, David A Harris

Aging Cell· October 2025

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The GLP-1 Era-What Comes After Bariatric Surgery?
Kate V Lauer, David A Harris, Luke M Funk

JAMA Surg· October 2025

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Growth Differentiation Factor 15 Elevation in the Central Nervous System Is Associated With Failure to Thrive in Alexander Disease.
Tracy L Hagemann, Michelle M Sonsalla, Cora Luzinski, Fernando Zacahua, David A Harris

Ann Clin Transl Neurol· September 2025

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Lysosomal Enhancement Prevents Infection with PrP, α-Synuclein & Tau Prions.
Robert C C Mercer, Nhat T T Le, Nadia A Mirza-Romero, Erin Flaherty, Joseph P DeFranco, David A Harris

bioRxiv· August 2025

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Fasting is required for many of the benefits of calorie restriction in the 3xTg mouse model of Alzheimer's disease.
Reji Babygirija, Jessica H Han, Michelle M Sonsalla, Ryan Matoska, Mariah F Calubag, David A Harris

Nat Commun· August 2025

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Defining hypoxia in cancer: A landmark evaluation of hypoxia gene expression signatures.
Matteo Di Giovannantonio, Fiona Hartley, Badran Elshenawy, Alessandro Barberis, Dan Hudson, David A Harris, Adrian L Harris, Benjamin H L Harris

Cell Genom· February 2025

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Tissue-specific effects of dietary protein on cellular senescence are mediated by branched-chain amino acids.
Mariah F Calubag, Ismail Ademi, Isaac Grunow, Lucia Breuer, Reji Babygirija, David A Harris

bioRxiv· January 2025

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Abnormal synaptic architecture in iPSC-derived neurons from a multi-generational family with genetic Creutzfeldt-Jakob disease.
Aldana D Gojanovich, Nhat T T Le, Robert C C Mercer, Seonmi Park, Bei Wu, David A Harris

Stem Cell Reports· October 2024

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Fasting is required for many of the benefits of calorie restriction in the 3xTg mouse model of Alzheimer's disease.
Reji Babygirija, Jessica H Han, Michelle M Sonsalla, Ryan Matoska, Mariah F Calubag, David A Harris

bioRxiv· September 2024

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A small intestinal bile acid modulates the gut microbiome to improve host metabolic phenotypes following bariatric surgery.
Yingjia Chen, Snehal N Chaudhari, David A Harris, Cullen F Roberts, Andrei Moscalu

Cell Host Microbe· August 2024

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Sigma Receptor Ligands Are Potent Antiprion Compounds that Act Independently of Sigma Receptor Binding.
Robert C C Mercer, Nhat T T Le, Douglas G Fraser, Mei C Q Houser, Aaron B Beeler, David A Harris

ACS Chem Neurosci· June 2024

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New role of fat-free mass in cancer risk linked with genetic predisposition.
Benjamin H L Harris, Matteo Di Giovannantonio, Ping Zhang, David A Harris, Simon R Lord, Adrian L Harris

Sci Rep· March 2024

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Sigma receptor ligands are potent anti-prion compounds that act independently of sigma receptor binding.
Robert C C Mercer, Nhat T T Le, Mei C Q Houser, Aaron B Beeler, David A Harris

bioRxiv· November 2023

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N-glycosylation is a potent regulator of prion protein neurotoxicity.
Kevin M Schilling, Pooja Jorwal, Natalia C Ubilla-Rodriguez, Tufa E Assafa, Jean R P Gatdula, David A Harris

J Biol Chem· September 2023

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Mechanisms of prion-induced toxicity.
Robert C C Mercer, David A Harris

Cell Tissue Res· April 2023

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Obesity: a perfect storm for carcinogenesis.
Benjamin H L Harris, Valentine M Macaulay, David A Harris, Paul Klenerman, Fredrik Karpe, Adrian L Harris

Cancer Metastasis Rev· September 2022

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The prion protein and its ligands: Insights into structure-function relationships.
Mohsin Shafiq, Stefano Da Vela, Ladan Amin, Neelam Younas, David A Harris

Biochim Biophys Acta Mol Cell Res· June 2022

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Comment on: The APB study: apixaban pharmacokinetics in bariatric patients before to 1 year after vertical sleeve gastrectomy or Roux-en-Y gastric bypass.
Jacqueline A Murtha, David A Harris, Luke M Funk

Surg Obes Relat Dis· May 2022

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Ligands binding to the prion protein induce its proteolytic release with therapeutic potential in neurodegenerative proteinopathies.
Luise Linsenmeier, Behnam Mohammadi, Mohsin Shafiq, Karl Frontzek, Julia Bär, David A Harris

Sci Adv· November 2021

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Aβ receptors specifically recognize molecular features displayed by fibril ends and neurotoxic oligomers.
Ladan Amin, David A Harris

Nat Commun· June 2021

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Weight and organ specific immune cell profiling of sleeve gastrectomy in mice.
David A Harris, Renuka Subramaniam, Todd Brenner, Ali Tavakkoli, Eric G Sheu

Metabolism· May 2021

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A microbial metabolite remodels the gut-liver axis following bariatric surgery.
Snehal N Chaudhari, James N Luo, David A Harris, Hassan Aliakbarian, Lina Yao

Cell Host Microbe· March 2021

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Structural Features of Heparin and Its Interactions With Cellular Prion Protein Measured by Surface Plasmon Resonance.
So Young Kim, Fuming Zhang, David A Harris, Robert J Linhardt

Front Mol Biosci· November 2020

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