Publications by authors named "David A Hildeman"

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Daytime SHP2 inhibitor dosing, when immune cell numbers are elevated, shrinks neurofibromas.
Niousha Ahmari, Kwangmin Choi, Jianqiang Wu, Tilat A Rizvi, Mark Jackson, David A Hildeman

Life Sci Alliance· December 2025

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Bile acids engage the SIPR-STAT3 signaling axis to modulate regulatory T cell responses in fibrosing cholangiopathies.
Ramesh Kudira, Zi F Yang, Immaculeta Osuji, Michelle S M A Damen, Annika Yang Vom Hofe, David A Hildeman

J Hepatol· November 2025

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Single-cell transcriptional landscape of liver transplant rejection reveals tissue persistence of clonally expanded, treatment-resistant T cells.
Anna L Peters, Erica A K DePasquale, Gousia Begum, Krishna M Roskin, Michael Kotliar, David A Hildeman

Am J Transplant· November 2025

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RNA helicase DDX3X promotes NK cell survival by supporting MCL1 expression.
Eshana Mukhopadhyay, Nora Lakes, Durga Krishnamurthy, Jasmine A Tuazon, David E Ohayon, David A Hildeman

J Immunol· October 2025

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CO-STIMULATORY BLOCKADE PREVENTS INTRAGRAFT ACCRUAL OF CLASS-SWITCHED, ACTIVATED B CELLS DESPITE FAILING TO PREVENT T-CELL MEDIATED REJECTION.
J Timothy Caldwell, Tiffany Shi, Ashley R Burg, Ashley Koby, Krishna M Roskin, David A Hildeman

bioRxiv· October 2025

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Gucy1α1 specifically marks kidney, heart, lung and liver fibroblasts.
Valeria Rudman-Melnick, Davy Vanhoutte, Kaitlynn Stowers, Michelle Sargent, Mike Adam, David A Hildeman

Sci Rep· November 2024

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Stimulator of interferon gene facilitates recruitment of effector CD8 T cells that drive neurofibromatosis type 1 nerve tumor initiation and maintenance.
Jay Pundavela, Samantha Anne Dinglasan, Melissa Touvron, Sarah A Hummel, Liang Hu, David A Hildeman

Sci Adv· October 2024

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Gucy1α1 specifically marks kidney, heart, lung and liver fibroblasts.
Valeria Rudman-Melnick, Davy Vanhoutte, Kaitlynn Stowers, Michelle Sargent, Mike Adam, David A Hildeman

Res Sq· August 2024

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Accelerating drug discovery and repurposing by combining transcriptional signature connectivity with docking.
Alexander W Thorman, James Reigle, Somchai Chutipongtanate, Juechen Yang, Behrouz Shamsaei, David A Hildeman

Sci Adv· August 2024

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Gucy1α1 specifically marks kidney, heart, lung and liver fibroblasts.
Valeria Rudman-Melnick, Davy Vanhoutte, Kaitlynn Stowers, Michelle Sargent, Mike Adam, David A Hildeman

bioRxiv· May 2024

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Defining the T cell transcriptional landscape in pediatric liver transplant rejection at single cell resolution.
Anna L Peters, Erica A K DePasquale, Gousia Begum, Krishna M Roskin, E Steve Woodle, David A Hildeman

bioRxiv· February 2024

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Prior viral infection primes cross-reactive CD8+ T cells that respond to mouse heart allografts.
M Eyad Khorki, Tiffany Shi, Eileen E Cianciolo, Ashley R Burg, P Chukwunalu Chukwuma, David A Hildeman

Front Immunol· December 2023

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Accumulation of immune-suppressive CD4 + T cells in aging - tempering inflammaging at the expense of immunity.
Alyssa L Thomas, Alzbeta Godarova, Joseph A Wayman, Emily R Miraldi, David A Hildeman

Semin Immunol· November 2023

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Antigen-specific decidual CD8+ T cells include distinct effector memory and tissue-resident memory cells.
Shweta Mahajan, Aria Alexander, Zachary Koenig, Nicholas Saba, Nina Prasanphanich, David A Hildeman

JCI Insight· September 2023

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Single-cell transcriptomic analysis of renal allograft rejection reveals insights into intragraft TCR clonality.
Tiffany Shi, Ashley R Burg, J Timothy Caldwell, Krishna M Roskin, Cyd M Castro-Rojas, David A Hildeman

J Clin Invest· July 2023

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Effects of invivo CXCR4 blockade and proteasome inhibition on bone marrow plasma cells in HLA-sensitized kidney transplant candidates.
Amy P Rossi, Simon Tremblay, Cyd M Castro-Rojas, Ashley A Burg, Krishna M Roskin, David A Hildeman

Am J Transplant· June 2023

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Apoptotic cell death in disease-Current understanding of the NCCD 2023.
Ilio Vitale, Federico Pietrocola, Emma Guilbaud, Stuart A Aaronson, John M Abrams, David A Hildeman

Cell Death Differ· May 2023

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An atlas of gene regulatory networks for memory CD4 T cells in youth and old age.
Joseph A Wayman, Alyssa Thomas, Anthony Bejjani, Alexander Katko, Maha Almanan, David A Hildeman

bioRxiv· April 2023

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Elevated CD153 Expression on Aged T Follicular Helper Cells is Vital for B cell Responses.
Alyssa L Thomas, Joseph A Wayman, Maha Almanan, Anthony T Bejjani, Emily R Miraldi, David A Hildeman

bioRxiv· April 2023

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Subset-specific and temporal control of effector and memory CD4+ T cell survival.
Sharmila Shanmuganad, Autumn Ferguson, Aditi Paranjpe, Eileen Elfers Cianciolo, Jonathan D Katz, David A Hildeman

bioRxiv· March 2023

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Single cell transcriptomic analysis of renal allograft rejection reveals novel insights into intragraft TCR clonality.
Tiffany Shi, Ashley R Burg, J Timothy Caldwell, Krishna Roskin, Cyd M Castro-Rojas, David A Hildeman

bioRxiv· February 2023

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Naturally-aged microglia exhibit phagocytic dysfunction accompanied by gene expression changes reflective of underlying neurologic disease.
Alyssa L Thomas, Maria A Lehn, Edith M Janssen, David A Hildeman, Claire A Chougnet

Sci Rep· November 2022

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Bcl-2 Is Necessary to Counteract Bim and Promote Survival of TCRαβCD8αα Intraepithelial Lymphocyte Precursors in the Thymus.
Sharmila Shanmuganad, Sarah A Hummel, Vivian Varghese, David A Hildeman

J Immunol· February 2022

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Implications of Inflammatory States on Dysfunctional Immune Responses in Aging and Obesity.
Alyssa L Thomas, Pablo C Alarcon, Senad Divanovic, Claire A Chougnet, David A Hildeman

Front Aging· September 2021

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Seroprevalence of SARS-CoV-2 infection in Cincinnati Ohio USA from August to December 2020.
Greg Davis, Allen J York, Willis Clark Bacon, Suh-Chin Lin, Monica Malone McNeal, David A Hildeman

PLoS One· July 2021

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