Publications by authors named "David A Jacques"

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The Human T-cell Leukemia Virus capsid protein is a potential drug target.
Ruijie Yu, Prabhjeet Phalora, Nan Li, Till Böcking, David Anthony Jacques

Nat Commun· December 2025

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The intersection of viral mimicry and nuclear entry.
Claire F Dickson, Prabhjeet Phalora, David A Jacques

Trends Biochem Sci· September 2025

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Pharmacologic hyperstabilisation of the HIV-1 capsid lattice induces capsid failure.
K M Rifat Faysal, James C Walsh, Nadine Renner, Chantal L Márquez, Vaibhav B Shah, David A Jacques

Elife· February 2024

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Statement in Support of: "Virology under the Microscope-a Call for Rational Discourse".
Peter Speck, Jason Mackenzie, Rowena A Bull, Barry Slobedman, Heidi Drummer, David A Jacques

mSphere· June 2023

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Statement in Support of: "Virology under the Microscope-a Call for Rational Discourse".
Peter Speck, Jason Mackenzie, Rowena A Bull, Barry Slobedman, Heidi Drummer, David A Jacques

mBio· June 2023

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Statement in Support of: "Virology under the Microscope-a Call for Rational Discourse".
Peter Speck, Jason Mackenzie, Rowena A Bull, Barry Slobedman, Heidi Drummer, David A Jacques

J Virol· May 2023

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Evasion of cGAS and TRIM5 defines pandemic HIV.
Lorena Zuliani-Alvarez, Morten L Govasli, Jane Rasaiyaah, Chris Monit, Stephen O Perry, David A Jacques

Nat Microbiol· November 2022

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Insights into HIV uncoating from single-particle imaging techniques.
Margaret J Zhang, Jeffrey H Stear, David A Jacques, Till Böcking

Biophys Rev· February 2022

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Rapid HIV-1 Capsid Interaction Screening Using Fluorescence Fluctuation Spectroscopy.
Derrick Lau, James C Walsh, Claire F Dickson, Andrew Tuckwell, Jeffrey H Stear, David A Jacques

Anal Chem· March 2021

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Target-induced clustering activates Trim-Away of pathogens and proteins.
Jingwei Zeng, Ana Filipa Santos, Aamir S Mukadam, Mariana Osswald, David A Jacques

Nat Struct Mol Biol· March 2021

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A lysine ring in HIV capsid pores coordinates IP6 to drive mature capsid assembly.
Nadine Renner, Donna L Mallery, K M Rifat Faysal, Wang Peng, David A Jacques

PLoS Pathog· February 2021

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MxB sensitivity of HIV-1 is determined by a highly variable and dynamic capsid surface.
Richard J Miles, Claire Kerridge, Laura Hilditch, Christopher Monit, David A Jacques

Elife· June 2020

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Self-Assembly of Fluorescent HIV Capsid Spheres for Detection of Capsid Binders.
Derrick Lau, James C Walsh, Amir Mousapasandi, Nicholas Ariotti, Vaibhav B Shah, David A Jacques

Langmuir· April 2020

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Fluorescence Biosensor for Real-Time Interaction Dynamics of Host Proteins with HIV-1 Capsid Tubes.
Derrick Lau, James C Walsh, Wang Peng, Vaibhav B Shah, Stuart Turville, David A Jacques

ACS Appl Mater Interfaces· September 2019

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The Human Immunodeficiency Virus Capsid Is More Than Just a Genome Package.
Leo C James, David A Jacques

Annu Rev Virol· September 2018

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Kinetics of HIV-1 capsid uncoating revealed by single-molecule analysis.
Chantal L Márquez, Derrick Lau, James Walsh, Vaibhav Shah, Conall McGuinness, David A Jacques

Elife· June 2018

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IP6 is an HIV pocket factor that prevents capsid collapse and promotes DNA synthesis.
Donna L Mallery, Chantal L Márquez, William A McEwan, Claire F Dickson, David A Jacques

Elife· May 2018

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2017 publication guidelines for structural modelling of small-angle scattering data from biomolecules in solution: an update.
Jill Trewhella, Anthony P Duff, Dominique Durand, Frank Gabel, J Mitchell Guss, David A Jacques

Acta Crystallogr D Struct Biol· September 2017

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Interactions between LHX3- and ISL1-family LIM-homeodomain transcription factors are conserved in Caenorhabditis elegans.
Mugdha Bhati, Estelle Llamosas, David A Jacques, Cy M Jeffries, Siavoush Dastmalchi

Sci Rep· July 2017

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HIV-1 uses dynamic capsid pores to import nucleotides and fuel encapsidated DNA synthesis.
David A Jacques, William A McEwan, Laura Hilditch, Amanda J Price, Greg J Towers

Nature· August 2016

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GATA1 directly mediates interactions with closely spaced pseudopalindromic but not distantly spaced double GATA sites on DNA.
Lorna Wilkinson-White, Krystal L Lester, Nina Ripin, David A Jacques, J Mitchell Guss

Protein Sci· October 2015

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The structure of haemoglobin bound to the haemoglobin receptor IsdH from Staphylococcus aureus shows disruption of the native α-globin haem pocket.
Claire F Dickson, David A Jacques, Robert T Clubb, J Mitchell Guss, David A Gell

Acta Crystallogr D Biol Crystallogr· June 2015

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Host cofactors and pharmacologic ligands share an essential interface in HIV-1 capsid that is lost upon disassembly.
Amanda J Price, David A Jacques, William A McEwan, Adam J Fletcher, Sebastian Essig

PLoS Pathog· October 2014

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Intracellular immunity: finding the enemy within--how cells recognize and respond to intracellular pathogens.
Jerry C H Tam, David A Jacques

J Leukoc Biol· August 2014

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The structure of α-haemoglobin in complex with a haemoglobin-binding domain from Staphylococcus aureus reveals the elusive α-haemoglobin dimerization interface.
Kaavya Krishna Kumar, David A Jacques, J Mitchell Guss, David A Gell

Acta Crystallogr F Struct Biol Commun· August 2014

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