Publications by authors named "David A Mackey"

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David A Mackey

April 2022

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Association of Polygenic Scores for Glaucoma With Measures of Retinal Ganglion Cell Integrity in Young and Older Adults.
Samantha Sze-Yee Lee, Santiago Diaz Torres, Gareth Lingham, Seyhan Yazar, Michael Hunter, David A Mackey

Am J Ophthalmol· January 2026

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Identification of blood-derived DNA methylation biomarkers of glaucoma and intraocular pressure measurements in three European ancestry cohorts including the Canadian longitudinal study on aging.
Xiaofan Jiang, Omar A Mahroo, Anthony P Khawaja, Dorota Skowronska-Krawczyk, David A Mackey

Epigenetics· December 2025

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Refractive Error Centile Curves for Asian and Western Children and Adolescents: An Individual Level Meta-Analysis.
Daniel Ian Flitcroft, Gareth Lingham, Gui-Shuang Ying, Hongguang Cui, David A Mackey

Invest Ophthalmol Vis Sci· December 2025

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Genomic structural equation Modeling analysis of glaucoma Endophenotypes: investigating genetic architecture and non-intraocular pressure mechanisms.
Maryam Marzban, Santiago Diaz-Torres, Jackson Thorp, Jue Sheng Ong, Anthony P Khawaja, David A Mackey

Hum Mol Genet· November 2025

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Advances in the genetics of refractive errors: Contributions from the CREAM consortium.
Sze Wai Rosa Li, Xi He, Louise Terry, Virginie J M Verhoeven, Samantha Sze-Yee Lee, David A Mackey

Acta Ophthalmol· November 2025

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Clinical Nomogram for Determining Expected Choroidal Thickness in Children With Myopia.
Ian Flitcroft, Gareth Lingham, Eoin Kerin, Ernest Kyei Nkansah, David A Mackey

Am J Ophthalmol· October 2025

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IMI-Myopia Genetics Report.
Mats Voogelaar, Milly S Tedja, Jeremy A Guggenheim, Seang-Mei Saw, Martha Tjon-Fo-Sang, David A Mackey

Invest Ophthalmol Vis Sci· October 2025

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Polygenic prediction of body mass index and obesity through the life course and across ancestries.
Roelof A J Smit, Kaitlin H Wade, Qin Hui, Joshua D Arias, Xianyong Yin, David A Mackey

Nat Med· September 2025

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A Multitrait Open-Angle Glaucoma Polygenic Risk Score Stratifies Risk of Glaucoma Diagnosis and Severity in Eyes with Pseudoexfoliation.
Antonia Kolovos, Ayub Qassim, Mark M Hassall, Henry N Marshall, Joshua Schmidt, David A Mackey

Ophthalmology· August 2025

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Large-scale GWAS of strabismus identifies risk loci and provides support for a link with maternal smoking.
Weixiong He, Peter J van der Most, Jue-Sheng Ong, Liang-Dar Hwang, Yeda Wu, David A Mackey

Nat Commun· August 2025

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Polygenic Risk Prediction for Normal-Tension Glaucoma.
Maryam Marzban, Santiago Diaz Torres, Regina Yu, Weixiong He, David A Mackey

Invest Ophthalmol Vis Sci· July 2025

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Evaluating Practical Approaches for Including MYOC Variants Alongside Common Variants for Genetics-Based Risk Stratification for Glaucoma.
Ngoc-Quynh Le, Weixiong He, Matthew H Law, Sarah E Medland, David A Mackey

Am J Ophthalmol· June 2025

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Family and genetic counseling in Leber hereditary optic neuropathy.
David A Mackey, Sandra E Staffieri, M Isabel G Lopez Sanchez, Lisa S Kearns

Ophthalmic Genet· April 2025

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Leber Hereditary Optic Neuropathy: Support, Genetic Prediction and Accurate Genetic Counselling Enhance Family Planning Choices.
Lisa S Kearns, Sandra E Staffieri, David A Mackey

Clin Exp Ophthalmol· April 2025

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Longitudinal Change in Retinal Nerve Fiber Layer Thickness and Intraocular Pressure in Young Adults.
Samantha Sze-Yee Lee, Gareth Lingham, Alex W Hewitt, David A Mackey

Transl Vis Sci Technol· April 2025

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Reply.
Abadh K Chaurasia, Connor J Greatbatch, Xikun Han, Puya Gharahkhani, David A Mackey

Ophthalmol Sci· April 2025

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Tracing ocular biometry and their heritability in twins in a hospital-based cohort in South India.
Padma Paul, Anika Amritanand, Smitha Jasper, Prem Doss, Prasanna Samuel, David A Mackey

Indian J Ophthalmol· March 2025

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Genome-wide association studies, Polygenic Risk Scores and Mendelian randomisation: an overview of common genetic epidemiology methods for ophthalmic clinicians.
Samantha Sze-Yee Lee, Fiona Stapleton, Stuart MacGregor, David A Mackey

Br J Ophthalmol· March 2025

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Pregnancy in women with mitochondrial disease-A literature review and suggested guidance for preconception and pregnancy care.
Lisa Hui, Pema Hayman, Ali Buckland, Michael C Fahey, David A Mackey

Aust N Z J Obstet Gynaecol· February 2025

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A large-scale genome-wide association meta-analysis for nevus count provides direct insights into the genetics of melanoma.
G J M S R Jayasinghe, Gu Zhu, Nirmala Pandeya, Catherine M Olsen, Nicholas G Martin, David A Mackey

medRxiv· February 2025

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A generalised computer vision model for improved glaucoma screening using fundus images.
Abadh K Chaurasia, Guei-Sheung Liu, Connor J Greatbatch, Puya Gharahkhani, Jamie E Craig, David A Mackey

Eye (Lond)· January 2025

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Developing and validating a comprehensive polygenic risk score to enhance keratoconus risk prediction.
Weixiong He, Urmo Võsa, Teele Palumaa, Jue-Sheng Ong, Santiago Diaz Torres, David A Mackey

Hum Mol Genet· January 2025

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Predictive Power of Polygenic Risk Scores for Intraocular Pressure or Vertical Cup-Disc Ratio.
Weixiong He, Samantha Sze-Yee Lee, Santiago Diaz Torres, Xikun Han, Puya Gharahkhani, David A Mackey

JAMA Ophthalmol· January 2025

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Genome-wide meta-analysis identifies 22 loci for normal tension glaucoma with significant overlap with high tension glaucoma.
Santiago Diaz-Torres, Weixiong He, Regina Yu, , Anthony P Khawaja, David A Mackey

Nat Commun· November 2024

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Uncovering genetic loci and biological pathways associated with age-related cataracts through GWAS meta-analysis.
Santiago Diaz-Torres, Samantha Sze-Yee Lee, Luis M García-Marín, Adrian I Campos, Garreth Lingham, David A Mackey

Nat Commun· October 2024

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