Publications by authors named "David A Nathanson"

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Tegavivint triggers TECR-dependent nonapoptotic cancer cell death.
Logan Leak, Ziwei Wang, Alby J Joseph, Brianna Johnson, Alyssa A Chan, David A Nathanson

Nat Chem Biol· December 2025

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Allogeneic stem cell-engineered EGFRvIII-specific CAR-NKT cells for treating glioblastoma with enhanced efficacy and safety.
Yan-Ruide Li, Yichen Zhu, Zhe Li, Xinyuan Shen, Tyler Halladay, David A Nathanson

Mol Ther· December 2025

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Advanced imaging characterization of post-chemoradiation glioblastoma stratified by diffusion MRI phenotypes known to predict favorable anti-VEGF response.
Francesco Sanvito, Irina Kryukov, Jingwen Yao, Ashley Teraishi, Catalina Raymond, David A Nathanson

J Neurooncol· July 2025

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BRD2 Bromodomain-Mediated Regulation of Cell State Plasticity Modulates Therapy Response in Glioblastoma.
Raghavendra Vadla, Brett Taylor, Yohei Miyake, Benjamin Lin, Daisuke Kawauchi, David A Nathanson

Neuro Oncol· July 2025

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Identifying and exploiting combinatorial synthetic lethality by characterizing adaptive kinome rewiring of EGFRvIII-driven glioblastoma.
Benjamin Lin, Abigail K Shelton, Erin Smithberger, Julia Ziebro, Kasey R Skinner, David A Nathanson

Acta Neuropathol Commun· June 2025

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A Human Tumor-Immune Organoid Model of Glioblastoma.
Shivani Baisiwala, Elisa Fazzari, Matthew X Li, Antoni Martija, Daria J Azizad, David A Nathanson

bioRxiv· June 2025

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Impact of corticosteroid administration on contrast-enhancing volume and diffusion MRI in treatment naïve glioblastoma.
Francesco Sanvito, Asher Kim, Catalina Raymond, Ashley Teraishi, Richard G Everson, David A Nathanson

Neuro Oncol· May 2025

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A comparative study of preclinical and clinical molecular imaging response to EGFR inhibition using osimertinib in glioblastoma.
Benjamin M Ellingson, Qunicy Okobi, Robert Chong, Rhea Plawat, Eva Zhao, David A Nathanson

Neurooncol Adv· February 2025

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Integrated molecular and functional characterization of the intrinsic apoptotic machinery identifies therapeutic vulnerabilities in glioma.
Elizabeth G Fernandez, Wilson X Mai, Kai Song, Nicholas A Bayley, Jiyoon Kim, David A Nathanson

Nat Commun· November 2024

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IL-13Rα2/TGF-β bispecific CAR-T cells counter TGF-β-mediated immune suppression and potentiate anti-tumor responses in glioblastoma.
Andrew J Hou, Ryan M Shih, Benjamin R Uy, Amanda Shafer, ZeNan L Chang, David A Nathanson

Neuro Oncol· October 2024

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Epigenetic Induction of Cancer-Testis Antigens and Endogenous Retroviruses at Single-Cell Level Enhances Immune Recognition and Response in Glioma.
Thomas J Lai, Lu Sun, Kevin Li, Terry J Prins, Janet Treger, David A Nathanson

Cancer Res Commun· July 2024

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Glioblastoma Neurovascular Progenitor Orchestrates Tumor Cell Type Diversity.
Elisa Fazzari, Daria J Azizad, Kwanha Yu, Weihong Ge, Matthew X Li, David A Nathanson

bioRxiv· July 2024

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D-2-HG Inhibits IDH1mut Glioma Growth via FTO Inhibition and Resultant m6A Hypermethylation.
Sean T Pianka, Tie Li, Terry J Prins, Blaine S C Eldred, Bryan M Kevan, David A Nathanson

Cancer Res Commun· March 2024

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F-Labeled brain-penetrant EGFR tyrosine kinase inhibitors for PET imaging of glioblastoma.
Maruthi Kumar Narayanam, Jonathan E Tsang, Shili Xu, David A Nathanson, Jennifer M Murphy

Chem Sci· December 2023

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M2 isoform of pyruvate kinase rewires glucose metabolism during radiation therapy to promote an antioxidant response and glioblastoma radioresistance.
Justine Bailleul, Yangjingyi Ruan, Lobna Abdulrahman, Andrew J Scott, Taha Yazal, David A Nathanson

Neuro Oncol· November 2023

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Depth of Radiographic Response and Time to Tumor Regrowth Predicts Overall Survival Following Anti-VEGF Therapy in Recurrent Glioblastoma.
Benjamin M Ellingson, Akifumi Hagiwara, Connor J Morris, Nicholas S Cho, Sonoko Oshima, David A Nathanson

Clin Cancer Res· October 2023

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Calculation of ATP production rates using the Seahorse XF Analyzer.
Brandon R Desousa, Kristen Ko Kim, Anthony E Jones, Andréa B Ball, Wei Y Hsieh, David A Nathanson

EMBO Rep· October 2023

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Differential Susceptibility of Ex Vivo Primary Glioblastoma Tumors to Oncolytic Effect of Modified Zika Virus.
Gustavo Garcia, Nikhil Chakravarty, Sophia Paiola, Estrella Urena, Priya Gyani, David A Nathanson

Cells· September 2023

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Glioblastoma Mesenchymal Transition and Invasion are Dependent on a NF-κB/BRD2 Chromatin Complex.
Raghavendra Vadla, Shunichiro Miki, Brett Taylor, Daisuke Kawauchi, Brandon M Jones, David A Nathanson

bioRxiv· July 2023

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CDKN2A deletion remodels lipid metabolism to prime glioblastoma for ferroptosis.
Jenna K Minami, Danielle Morrow, Nicholas A Bayley, Elizabeth G Fernandez, Jennifer J Salinas, David A Nathanson

Cancer Cell· June 2023

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Multi-nuclear sodium, diffusion, and perfusion MRI in human gliomas.
Nicholas S Cho, Francesco Sanvito, Shruti Thakuria, Chencai Wang, Akifumi Hagiwara, David A Nathanson

J Neurooncol· June 2023

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Corrigendum to: EGFR, the Lazarus target for precision oncology in glioblastoma.
Benjamin Lin, Julia Ziebro, Erin Smithberger, Kasey R Skinner, Eva Zhao, David A Nathanson

Neuro Oncol· January 2023

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EGFR, the Lazarus target for precision oncology in glioblastoma.
Benjamin Lin, Julia Ziebro, Erin Smithberger, Kasey R Skinner, Eva Zhao, David A Nathanson

Neuro Oncol· December 2022

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Ferroptosis inhibition by lysosome-dependent catabolism of extracellular protein.
David A Armenta, Nouf N Laqtom, Grace Alchemy, Wentao Dong, Danielle Morrow, David A Nathanson

Cell Chem Biol· November 2022

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Pathway-based approach reveals differential sensitivity to E2F1 inhibition in glioblastoma.
Alvaro G Alvarado, Kaleab Tessema, Sree Deepthi Muthukrishnan, Mackenzie Sober, Riki Kawaguchi, David A Nathanson

Cancer Res Commun· September 2022

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