Publications by authors named "David Akhavan"

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Recapitulating the immune microenvironment in pediatric brain cancer: preclinical modeling strategies.
Adip G Bhargav, Joseph S Domino, David Akhavan, Jo Ling Goh

Front Immunol· October 2025

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A regularized-multi-field optimization algorithm for robust IMPT.
Ying Luo, Chao Wang, Ya-Nan Zhu, Wangyao Li, Daniel Johnson, David Akhavan

Med Phys· August 2025

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Proton GRID and LATTICE treatment planning techniques for clinical liver SFRT treatments.
Jufri Setianegara, Ya-Nan Zhu, Mingyao Zhu, Rajeev Badkul, Tianyu Zhao, David Akhavan

Phys Med Biol· May 2025

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Stereotactic cardiac radiotherapy for refractory ventricular tachycardia in structural heart disease patients: a systematic review.
Amulya Gupta, Zeeshan Sattar, Nourhan Chaaban, Sagar Ranka, Cameron Carlson, David Akhavan

Europace· December 2024

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Proton ARC based LATTICE radiation therapy: feasibility study, energy layer optimization and LET optimization.
Ya-Nan Zhu, Weijie Zhang, Jufri Setianegara, Yuting Lin, Erik Traneus, David Akhavan

Phys Med Biol· October 2024

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Evaluation of the Immunomodulatory Effects of Radiation for Chimeric Antigen Receptor T Cell Therapy in Glioblastoma Multiforme.
David Akhavan, Siddharth Subham, John D Jeppson, Brenda Aguilar, Robyn A Wong

Cells· June 2024

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Cardiac stereotactic radiotherapy for refractory ventricular tachycardia in a patient with wireless left ventricular endocardial stimulation system.
Sania Jiwani, David Akhavan, Madhu Reddy, Amit Noheria

HeartRhythm Case Rep· November 2023

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Rapid In Vitro Cytotoxicity Evaluation of Jurkat Expressing Chimeric Antigen Receptor using Fluorescent Imaging.
Siddharth Subham, John D Jeppson, Benjamin K Gibbs, Jacqueline Babai, Riza Alker, David Akhavan

J Vis Exp· October 2023

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Advances in computational and translational approaches for malignant glioma.
Adip G Bhargav, Joseph S Domino, Anthony M Alvarado, Chad A Tuchek, David Akhavan

Front Physiol· June 2023

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EGFR as a potent CAR T target in triple negative breast cancer brain metastases.
Siddharth Subham, John D Jeppson, Colette Worcester, Bryan Schatmeyer, Jie Zhao, David Akhavan

Breast Cancer Res Treat· January 2023

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The Effects of Time to Treatment Initiation for Patients With Non-small-cell Lung Cancer in the United States.
Taylor R Cushman, Bernard Jones, David Akhavan, Chad G Rusthoven, Vivek Verma

Clin Lung Cancer· January 2021

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Phase I Study of Yttrium-90 Radiolabeled M5A Anti-Carcinoembryonic Antigen Humanized Antibody in Patients with Advanced Carcinoembryonic Antigen Producing Malignancies.
David Akhavan, Paul Yazaki, Dave Yamauchi, Jennifer Simpson, Paul H Frankel

Cancer Biother Radiopharm· February 2020

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CAR T cells for brain tumors: Lessons learned and road ahead.
David Akhavan, Darya Alizadeh, Dongrui Wang, Michael R Weist, Jennifer K Shepphird

Immunol Rev· July 2019

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Shifting paradigms: whole brain radiation therapy versus stereotactic radiosurgery for brain metastases.
Ashwin Shinde, David Akhavan, Mina Sedrak, Scott Glaser, Arya Amini

CNS Oncol· March 2019

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Disparities Predict for Higher Rates of Cut-through Hysterectomies in Locally Advanced Cervical Cancer.
Arya Amini, Tyler P Robin, Chad G Rusthoven, Tracey E Schefter, David Akhavan

Am J Clin Oncol· January 2019

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mTOR complex 2 controls glycolytic metabolism in glioblastoma through FoxO acetylation and upregulation of c-Myc.
Kenta Masui, Kazuhiro Tanaka, David Akhavan, Ivan Babic, Beatrice Gini

Cell Metab· November 2013

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The mTOR kinase inhibitors, CC214-1 and CC214-2, preferentially block the growth of EGFRvIII-activated glioblastomas.
Beatrice Gini, Ciro Zanca, Deliang Guo, Tomoo Matsutani, Kenta Masui, David Akhavan

Clin Cancer Res· October 2013

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EGFR mutation-induced alternative splicing of Max contributes to growth of glycolytic tumors in brain cancer.
Ivan Babic, Erik S Anderson, Kazuhiro Tanaka, Deliang Guo, Kenta Masui, David Akhavan

Cell Metab· June 2013

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An essential requirement for the SCAP/SREBP signaling axis to protect cancer cells from lipotoxicity.
Kevin J Williams, Joseph P Argus, Yue Zhu, Moses Q Wilks, Beth N Marbois, David Akhavan

Cancer Res· May 2013

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De-repression of PDGFRβ transcription promotes acquired resistance to EGFR tyrosine kinase inhibitors in glioblastoma patients.
David Akhavan, Alexandra L Pourzia, Alex A Nourian, Kevin J Williams, David Nathanson

Cancer Discov· May 2013

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Pilot study on "pericytic mimicry" and potential embryonic/stem cell properties of angiotropic melanoma cells interacting with the abluminal vascular surface.
Claire Lugassy, Madhuri Wadehra, Xinmin Li, Mirko Corselli, David Akhavan

Cancer Microenviron· April 2013

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Oncogenic EGFR signaling activates an mTORC2-NF-κB pathway that promotes chemotherapy resistance.
Kazuhiro Tanaka, Ivan Babic, David Nathanson, David Akhavan, Deliang Guo

Cancer Discov· November 2011

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An LXR agonist promotes glioblastoma cell death through inhibition of an EGFR/AKT/SREBP-1/LDLR-dependent pathway.
Deliang Guo, Felicia Reinitz, Mary Youssef, Cynthia Hong, David Nathanson, David Akhavan

Cancer Discov· October 2011

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Activation of Src induces mitochondrial localisation of de2-7EGFR (EGFRvIII) in glioma cells: implications for glucose metabolism.
Anna N Cvrljevic, David Akhavan, Min Wu, Paul Martinello, Frank B Furnari

J Cell Sci· September 2011

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mTOR signaling in glioblastoma: lessons learned from bench to bedside.
David Akhavan, Timothy F Cloughesy, Paul S Mischel

Neuro Oncol· August 2010

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