Publications by authors named "David Astling"

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Crossing the Halfway Point: Aptamer-Based, Highly Multiplexed Assay for the Assessment of the Proteome.
Stephan Kraemer, Daniel J Schneider, Clare Paterson, Darryl Perry, Matthew J Westacott, David P Astling

J Proteome Res· November 2024

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Olduvai domain expression downregulates mitochondrial pathways: implications for human brain evolution and neoteny.
Jonathon G Keeney, David Astling, Vanessa Andries, Karl Vandepoele, Nathan Anderson

bioRxiv· October 2024

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Prediction of Cardiometabolic Health Through Changes in Plasma Proteins With Intentional Weight Loss in the DiRECT and DIADEM-I Randomized Clinical Trials of Type 2 Diabetes Remission.
Naveed Sattar, Shahrad Taheri, David P Astling, Jessica Chadwick, Michael A Hinterberg

Diabetes Care· November 2023

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A proteomic surrogate for cardiovascular outcomes that is sensitive to multiple mechanisms of change in risk.
Stephen A Williams, Rachel Ostroff, Michael A Hinterberg, Josef Coresh, Christie M Ballantyne, David Astling

Sci Transl Med· April 2022

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Genome-wide analysis of copy number variants and normal facial variation in a large cohort of Bantu Africans.
Megan Null, Feyza Yilmaz, David Astling, Hung-Chun Yu, Joanne B Cole

HGG Adv· January 2022

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Genome-wide copy number variations in a large cohort of bantu African children.
Feyza Yilmaz, Megan Null, David Astling, Hung-Chun Yu, Joanne Cole

BMC Med Genomics· May 2021

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Modified nucleotides may have enhanced early RNA catalysis.
Steven K Wolk, Wesley S Mayfield, Amy D Gelinas, David Astling, Jessica Guillot

Proc Natl Acad Sci U S A· April 2020

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Draft Genome Sequence of the Biofuel-Relevant Microalga Desmodesmus armatus.
Eric P Knoshaug, Ambarish Nag, David P Astling, Damien Douchi, Lieve M L Laurens

Microbiol Resour Announc· February 2020

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Intrauterine growth restriction decreases NF-κB signaling in fetal pulmonary artery endothelial cells of fetal sheep.
R Blair Dodson, Kyle N Powers, Jason Gien, Paul J Rozance, Gregory Seedorf, David Astling

Am J Physiol Lung Cell Mol Physiol· September 2018

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High-efficiency RNA-based reprogramming of human primary fibroblasts.
Igor Kogut, Sandra M McCarthy, Maryna Pavlova, David P Astling, Xiaomi Chen

Nat Commun· February 2018

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Genome Replication in Independent of Cdc6 and an Origin of Replication.
Alexandra M Gehring, David P Astling, Rie Matsumi, Brett W Burkhart, Zvi Kelman

Front Microbiol· October 2017

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High resolution measurement of DUF1220 domain copy number from whole genome sequence data.
David P Astling, Ilea E Heft, Kenneth L Jones, James M Sikela

BMC Genomics· August 2017

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CNS Aquaporin-4-specific B cells connect with multiple B-cell compartments in neuromyelitis optica spectrum disorder.
Markus C Kowarik, David Astling, Christiane Gasperi, Scott Wemlinger, Hannah Schumann

Ann Clin Transl Neurol· June 2017

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Profiling Chlamydomonas metabolism under dark, anoxic H2-producing conditions using a combined proteomic, transcriptomic, and metabolomic approach.
Venkataramanan Subramanian, Alexandra Dubini, David P Astling, Lieve M L Laurens, William M Old

J Proteome Res· December 2014

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Resistance to ROS1 inhibition mediated by EGFR pathway activation in non-small cell lung cancer.
Kurtis D Davies, Sakshi Mahale, David P Astling, Dara L Aisner, Anh T Le

PLoS One· October 2014

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Finished sequence and assembly of the DUF1220-rich 1q21 region using a haploid human genome.
Majesta O'Bleness, Veronica B Searles, C Michael Dickens, David Astling, Derek Albracht

BMC Genomics· May 2014

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Phase I study of oral rigosertib (ON 01910.Na), a dual inhibitor of the PI3K and Plk1 pathways, in adult patients with advanced solid malignancies.
Daniel W Bowles, Jennifer R Diamond, Elaine T Lam, Colin D Weekes, David P Astling

Clin Cancer Res· March 2014

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The dual pathway inhibitor rigosertib is effective in direct patient tumor xenografts of head and neck squamous cell carcinomas.
Ryan T Anderson, Stephen B Keysar, Daniel W Bowles, Magdalena J Glogowska, David P Astling

Mol Cancer Ther· October 2013

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A patient tumor transplant model of squamous cell cancer identifies PI3K inhibitors as candidate therapeutics in defined molecular bins.
Stephen B Keysar, David P Astling, Ryan T Anderson, Brian W Vogler, Daniel W Bowles

Mol Oncol· August 2013

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Obesity and overfeeding affecting both tumor and systemic metabolism activates the progesterone receptor to contribute to postmenopausal breast cancer.
Erin D Giles, Elizabeth A Wellberg, David P Astling, Steven M Anderson, Ann D Thor

Cancer Res· December 2012

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Localization of a bacterial cytoplasmic receptor is dynamic and changes with cell-cell contacts.
Emilia M F Mauriello, David P Astling, Oleksii Sliusarenko, David R Zusman

Proc Natl Acad Sci U S A· March 2009

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Differential effects of chemoreceptor methylation-domain mutations on swarming and development in the social bacterium Myxococcus xanthus.
David P Astling, Josephine Y Lee, David R Zusman

Mol Microbiol· January 2006

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