Publications by authors named "David B Langley"

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I-motif DNA structures are formed in the nuclei of human cells.
Mahdi Zeraati, David B Langley, Peter Schofield, Aaron L Moye, Romain Rouet, William E Hughes, Tracy M Bryan, Marcel E Dinger, Daniel Christ

Nat Chem· June 2018

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Affinity maturation endows potent activity onto class 6 SARS-CoV-2 broadly neutralizing antibodies.
Ohan Mazigi, David B Langley, Jake Y Henry, Deborah L Burnett, Meghna Sobti

Proc Natl Acad Sci U S A· January 2025

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Broadly neutralizing SARS-CoV-2 antibodies through epitope-based selection from convalescent patients.
Romain Rouet, Jake Y Henry, Matt D Johansen, Meghna Sobti, Harikrishnan Balachandran, David B Langley

Nat Commun· February 2023

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Genetic and structural basis of the human anti-α-galactosyl antibody response.
David B Langley, Peter Schofield, Damien Nevoltris, Jennifer Jackson, Katherine J L Jackson

Proc Natl Acad Sci U S A· July 2022

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Crystal structures of human neuropeptide Y (NPY) and peptide YY (PYY).
David B Langley, Peter Schofield, Jenny Jackson, Herbert Herzog, Daniel Christ

Neuropeptides· April 2022

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Immunizations with diverse sarbecovirus receptor-binding domains elicit SARS-CoV-2 neutralizing antibodies against a conserved site of vulnerability.
Deborah L Burnett, Katherine J L Jackson, David B Langley, Anupria Aggrawal, Alberto Ospina Stella

Immunity· December 2021

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Surface-associated antigen induces permeabilization of primary mouse B-cells and lysosome exocytosis facilitating antigen uptake and presentation to T-cells.
Fernando Y Maeda, Jurriaan Jh van Haaren, David B Langley, Daniel Christ, Norma W Andrews

Elife· October 2021

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Genomic Spectrum and Phenotypic Heterogeneity of Human IL-21 Receptor Deficiency.
Deniz Cagdas, Daniel Mayr, Safa Baris, Lisa Worley, David B Langley

J Clin Immunol· August 2021

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Potent SARS-CoV-2 binding and neutralization through maturation of iconic SARS-CoV-1 antibodies.
Romain Rouet, Ohan Mazigi, Gregory J Walker, David B Langley, Meghna Sobti

MAbs· May 2021

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Conformational diversity facilitates antibody mutation trajectories and discrimination between foreign and self-antigens.
Deborah L Burnett, Peter Schofield, David B Langley, Jennifer Jackson, Katherine Bourne

Proc Natl Acad Sci U S A· September 2020

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Lymphoma Driver Mutations in the Pathogenic Evolution of an Iconic Human Autoantibody.
Mandeep Singh, Katherine J L Jackson, Jing J Wang, Peter Schofield, Matt A Field, David B Langley

Cell· March 2020

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Protein A superantigen: structure, engineering and molecular basis of antibody recognition.
Ohan Mazigi, Peter Schofield, David B Langley, Daniel Christ

Protein Eng Des Sel· December 2019

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Denisovan, modern human and mouse TNFAIP3 alleles tune A20 phosphorylation and immunity.
Nathan W Zammit, Owen M Siggs, Paul E Gray, Keisuke Horikawa, David B Langley

Nat Immunol· October 2019

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Human Antibody Bispecifics through Phage Display Selection.
Ansha Luthra, David B Langley, Peter Schofield, Jennifer Jackson, Mahmoud Abdelatti

Biochemistry· April 2019

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Next-Generation Sequencing of Antibody Display Repertoires.
Romain Rouet, Katherine J L Jackson, David B Langley, Daniel Christ

Front Immunol· March 2019

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Crystal structure of duck egg lysozyme isoform II (DEL-II).
David B Langley, Daniel Christ

BMC Struct Biol· August 2018

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Germinal center antibody mutation trajectories are determined by rapid self/foreign discrimination.
Deborah L Burnett, David B Langley, Peter Schofield, Jana R Hermes, Tyani D Chan

Science· April 2018

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Structural basis of antigen recognition: crystal structure of duck egg lysozyme.
David Brent Langley, Ben Crossett, Peter Schofield, Jenny Jackson, Mahdi Zeraati

Acta Crystallogr D Struct Biol· November 2017

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Cytosolic Recognition of RNA Drives the Immune Response to Heterologous Erythrocytes.
Claudia Loetsch, Joanna Warren, Adrienne Laskowski, Rodrigo Vazquez-Lombardi, Christoph Jandl, David B Langley

Cell Rep· November 2017

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Structural reconstruction of protein ancestry.
Romain Rouet, David B Langley, Peter Schofield, Mary Christie, Brendan Roome

Proc Natl Acad Sci U S A· April 2017

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Preparing monodisperse macromolecular samples for successful biological small-angle X-ray and neutron-scattering experiments.
Cy M Jeffries, Melissa A Graewert, Clément E Blanchet, David B Langley, Andrew E Whitten

Nat Protoc· November 2016

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Structure of GUN4 from Chlamydomonas reinhardtii.
Shabnam Tarahi Tabrizi, David B Langley, Stephen J Harrop, Anthony P Duff, Robert D Willows

Acta Crystallogr F Struct Biol Commun· August 2015

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Structural basis for partial redundancy in a class of transcription factors, the LIM homeodomain proteins, in neural cell type specification.
Morgan S Gadd, Mugdha Bhati, Cy M Jeffries, David B Langley, Jill Trewhella

J Biol Chem· December 2011

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Structural basis for hemoglobin capture by Staphylococcus aureus cell-surface protein, IsdH.
Kaavya Krishna Kumar, David A Jacques, Gleb Pishchany, Tom Caradoc-Davies, Thomas Spirig, David B Langley

J Biol Chem· November 2011

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The structure of TTHA0988 from Thermus thermophilus, a KipI-KipA homologue incorrectly annotated as an allophanate hydrolase.
David A Jacques, David B Langley, Seiki Kuramitsu, Shigeyuki Yokoyama, Jill Trewhella

Acta Crystallogr D Biol Crystallogr· February 2011

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