Publications by authors named "David Barras"

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Neoantigen-specific CD8 T cells with high structural avidity preferentially reside in and eliminate tumors.
Julien Schmidt, Johanna Chiffelle, Marta A S Perez, Morgane Magnin, Sara Bobisse, Marion Arnaud, Raphael Genolet, Julien Cesbron, David Barras, Blanca Navarro Rodrigo

Nat Commun· June 2023

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Tissue specificity and chromosomal alterations shape divergent immune programs in HRD tumors.
Doga C Gulhan, David Barras, Marco Mina, Eleonora Ghisoni, Yoo-Na Kim

bioRxiv· October 2025

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Zinc availability in the tumor microenvironment dictates anti-PD1 response in tumors via increased macrophage phagocytosis.
Raquel Buj, Aidan R Cole, Jeff Danielson, Jimmy Xu, Drew Hurd, David Barras

bioRxiv· August 2025

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Myeloid cell networks govern re-establishment of original immune landscapes in recurrent ovarian cancer.
Eleonora Ghisoni, Fabrizio Benedetti, Aspram Minasyan, Mathieu Desbuisson, Paula Cunnea, David Barras

Cancer Cell· August 2025

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Identification of clinically relevant T cell receptors for personalized T cell therapy using combinatorial algorithms.
Rémy Pétremand, Johanna Chiffelle, Sara Bobisse, Marta A S Perez, Julien Schmidt, David Barras

Nat Biotechnol· March 2025

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Author Correction: Identification of clinically relevant T cell receptors for personalized T cell therapy using combinatorial algorithms.
Rémy Pétremand, Johanna Chiffelle, Sara Bobisse, Marta A S Perez, Julien Schmidt, David Barras

Nat Biotechnol· March 2025

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Cancer cells impair monocyte-mediated T cell stimulation to evade immunity.
Anais Elewaut, Guillem Estivill, Felix Bayerl, Leticia Castillon, Maria Novatchkova, David Barras

Nature· January 2025

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Predicting Antigen-Specificities of Orphan T Cell Receptors from Cancer Patients with TCRpcDist.
Marta A S Perez, Johanna Chiffelle, Sara Bobisse, Francesca Mayol-Rullan, Marine Bugnon, David Barras

Adv Sci (Weinh)· October 2024

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Tumor-reactive T cell clonotype dynamics underlying clinical response to TIL therapy in melanoma.
Johanna Chiffelle, David Barras, Rémy Pétremand, Angela Orcurto, Sara Bobisse

Immunity· October 2024

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PGE inhibits TIL expansion by disrupting IL-2 signalling and mitochondrial function.
Matteo Morotti, Alizee J Grimm, Helen Carrasco Hope, Marion Arnaud, Mathieu Desbuisson, David Barras

Nature· May 2024

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Response to tumor-infiltrating lymphocyte adoptive therapy is associated with preexisting CD8 T-myeloid cell networks in melanoma.
David Barras, Eleonora Ghisoni, Johanna Chiffelle, Angela Orcurto, Julien Dagher

Sci Immunol· February 2024

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Predicting response to immune checkpoint blockade therapy among mismatch repair-deficient patients using mutational signatures.
Doga C Gulhan, Vinay Viswanadham, Francesc Muyas, Hu Jin, Michael B Foote, David Barras

medRxiv· January 2024

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A phase 1 trial of adoptive transfer of vaccine-primed autologous circulating T cells in ovarian cancer.
Sara Bobisse, Valentina Bianchi, Janos L Tanyi, Apostolos Sarivalasis, Edoardo Missiaglia, David Barras

Nat Cancer· October 2023

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Connexins orchestrate progression of breast cancer metastasis to the brain by promoting FAK activation.
Girieca Lorusso, Christof B Wyss, François Kuonen, Nicola Vannini, Clotilde Billottet, David Barras

Sci Transl Med· September 2022

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Apelin-driven endothelial cell migration sustains intestinal progenitor cells and tumor growth.
Jeremiah Bernier-Latmani, Christophe Cisarovsky, Samantha Mahfoud, Simone Ragusa, Isabelle Dupanloup, David Barras

Nat Cardiovasc Res· May 2022

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Low-Dose Radiotherapy Reverses Tumor Immune Desertification and Resistance to Immunotherapy.
Fernanda G Herrera, Catherine Ronet, Maria Ochoa de Olza, David Barras, Isaac Crespo

Cancer Discov· January 2022

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Myeloid antigen-presenting cell niches sustain antitumor T cells and license PD-1 blockade via CD28 costimulation.
Jaikumar Duraiswamy, Riccardo Turrini, Aspram Minasyan, David Barras, Isaac Crespo

Cancer Cell· December 2021

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Unsupervised Analysis of Flow Cytometry Data in a Clinical Setting Captures Cell Diversity and Allows Population Discovery.
Petra Baumgaertner, Martial Sankar, Fernanda Herrera, Fabrizio Benedetti, David Barras

Front Immunol· September 2021

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Cell-autonomous inflammation of BRCA1-deficient ovarian cancers drives both tumor-intrinsic immunoreactivity and immune resistance via STING.
Marine Bruand, David Barras, Marco Mina, Eleonora Ghisoni, Matteo Morotti

Cell Rep· July 2021

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Gain of HIF1 Activity and Loss of miRNA Promote Breast Cancer Metastasis to the Brain via the PDGF/PDGFR Axis.
Christof B Wyss, Nathalie Duffey, Sanam Peyvandi, David Barras, Amaïa Martinez Usatorre

Cancer Res· February 2021

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The Interleukin 22 Pathway Interacts with Mutant KRAS to Promote Poor Prognosis in Colon Cancer.
Sarah McCuaig, David Barras, Elizabeth H Mann, Matthias Friedrich, Samuel J Bullers

Clin Cancer Res· August 2020

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Antiangiogenic immunotherapy suppresses desmoplastic and chemoresistant intestinal tumors in mice.
Simone Ragusa, Borja Prat-Luri, Alejandra González-Loyola, Sina Nassiri, Mario Leonardo Squadrito, David Barras

J Clin Invest· March 2020

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Cooperation between Constitutive and Inducible Chemokines Enables T Cell Engraftment and Immune Attack in Solid Tumors.
Denarda Dangaj, Marine Bruand, Alizée J Grimm, Catherine Ronet, David Barras

Cancer Cell· June 2019

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RasGRP1 is a potential biomarker to stratify anti-EGFR therapy response in colorectal cancer.
Oghenekevwe M Gbenedio, Caroline Bonnans, Delphine Grun, Chih-Yang Wang, Ace J Hatch, David Barras

JCI Insight· June 2019

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Tumor Landscapes: β-Catenin Drives Immune Desertification.
Denarda Dangaj, David Barras, George Coukos

Clin Cancer Res· May 2019

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