Publications by authors named "David Bartkovitz"

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Discovery of potent and selective spiroindolinone MDM2 inhibitor, RO8994, for cancer therapy.
Zhuming Zhang, Qingjie Ding, Jin-Jun Liu, Jing Zhang, Nan Jiang, David Bartkovitz

Bioorg Med Chem· August 2014

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Discovery of Potent and Orally Active p53-MDM2 Inhibitors RO5353 and RO2468 for Potential Clinical Development.
Zhuming Zhang, Xin-Jie Chu, Jin-Jun Liu, Qingjie Ding, Jing Zhang, David Bartkovitz

ACS Med Chem Lett· February 2014

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Discovery of RG7388, a potent and selective p53-MDM2 inhibitor in clinical development.
Qingjie Ding, Zhuming Zhang, Jin-Jun Liu, Nan Jiang, Jing Zhang, David Bartkovitz

J Med Chem· July 2013

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Identification of novel, potent and selective inhibitors of Polo-like kinase 1.
Shaoqing Chen, David Bartkovitz, Jianping Cai, Yi Chen, Zhi Chen

Bioorg Med Chem Lett· January 2012

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Discovery of [4-Amino-2-(1-methanesulfonylpiperidin-4-ylamino)pyrimidin-5-yl](2,3-difluoro-6- methoxyphenyl)methanone (R547), a potent and selective cyclin-dependent kinase inhibitor with significant in vivo antitumor activity.
Xin-Jie Chu, Wanda DePinto, David Bartkovitz, Sung-Sau So, Binh T Vu

J Med Chem· November 2006

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Preparation of human Melanocortin-4 receptor agonist libraries: linear peptides X-Y-DPhe7-Arg8-Trp(or 2-Nal)9-Z-NH2.
Adrian Wai-Hing Cheung, Lida Qi, Vijay Gore, Xin-Jie Chu, David Bartkovitz

Bioorg Med Chem Lett· December 2005

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Discovery of 1-amino-4-phenylcyclohexane-1-carboxylic acid and its influence on agonist selectivity between human melanocortin-4 and -1 receptors in linear pentapeptides.
Xin-Jie Chu, David Bartkovitz, Waleed Danho, Joseph Swistok, Adrian Wai-Hing Cheung

Bioorg Med Chem Lett· November 2005

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