Publications by authors named "David Bechard"

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Novel PD-1-targeted, activity-optimized IL-15 mutein SOT201 acting in cis provides antitumor activity superior to PD1-IL2v.
Hana Matuskova, Pavel Marasek, Vladyslav Mazhara, Ekaterina Simonova, Lucie Kosinova

J Immunother Cancer· April 2025

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Nanrilkefusp alfa (SOT101), an IL-15 receptor βγ superagonist, as a single agent or with anti-PD-1 in patients with advanced cancers.
Stephane Champiat, Elena Garralda, Vladimir Galvao, Philippe A Cassier, Carlos Gomez-Roca, David Bechard

Cell Rep Med· February 2025

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SOT101 induces NK cell cytotoxicity and potentiates antibody-dependent cell cytotoxicity and anti-tumor activity.
Zuzana Antosova, Nada Podzimkova, Jakub Tomala, Katerina Augustynkova, Katerina Sajnerova, David Bechard

Front Immunol· October 2022

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IL-15 superagonist RLI has potent immunostimulatory properties on NK cells: implications for antimetastatic treatment.
Mélanie Desbois, Coralie Béal, Mélinda Charrier, Benjamin Besse, Guillaume Meurice

J Immunother Cancer· June 2020

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IL-15 Trans-Signaling with the Superagonist RLI Promotes Effector/Memory CD8+ T Cell Responses and Enhances Antitumor Activity of PD-1 Antagonists.
Mélanie Desbois, Pauline Le Vu, Clélia Coutzac, Elie Marcheteau, Coralie Béal

J Immunol· July 2016

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Highly potent anti-CD20-RLI immunocytokine targeting established human B lymphoma in SCID mouse.
Marie Vincent, Géraldine Teppaz, Laurie Lajoie, Véronique Solé, Anne Bessard

MAbs· February 2015

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Overexpression of endocan induces tumor formation.
Arnaud Scherpereel, Thibaut Gentina, Bogdan Grigoriu, Stéphanie Sénéchal, Anne Janin

Cancer Res· September 2003

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