Publications by authors named "David Broadhurst"

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Diverse diagnostic and management approaches for acute rheumatic fever in Australia and New Zealand: findings of a prospective clinical study.
Ruwani Peiris, Rachel Webb, Julie Bennett, Jennifer Yan, Joshua Reginald Francis, David Broadhurst

BMJ Open· July 2025

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Exploring the Varied Clinical Presentation of Pediatric Asthma through the Metabolome.
Kevin M Mendez, Priyadarshini Kachroo, Nicole Prince, Mengna Huang, Margaret Cote, David I Broadhurst

Am J Respir Crit Care Med· May 2025

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A roadmap to precision medicine through post-genomic electronic medical records.
Kevin M Mendez, Stacey N Reinke, Rachel S Kelly, Qingwen Chen, Mark Su, David I Broadhurst

Nat Commun· February 2025

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Workshop report - interdisciplinary metabolomic epidemiology: the pathway to clinical translation.
Krista A Zanetti, Lining Guo, Deeba Husain, Rachel S Kelly, Jessica Lasky-Su, David Broadhurst

Metabolomics· May 2024

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Metabolite signatures associated with microRNA miR-143-3p serve as drivers of poor lung function trajectories in childhood asthma.
Kevin M Mendez, Sofina Begum, Anshul Tiwari, Rinku Sharma, Qingwen Chen, David I Broadhurst

EBioMedicine· April 2024

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Lipopolysaccharide-induced interferon response networks at birth are predictive of severe viral lower respiratory infections in the first year of life.
James F Read, Michael Serralha, Danny Mok, Barbara J Holt, Mark Cruickshank, David I Broadhurst

Front Immunol· August 2022

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Metabolomics reveals mouse plasma metabolite responses to acute exercise and effects of disrupting AMPK-glycogen interactions.
Mehdi R Belhaj, Nathan G Lawler, John A Hawley, David I Broadhurst, Nolan J Hoffman

Front Mol Biosci· August 2022

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Urinary metabotype of severe asthma evidences decreased carnitine metabolism independent of oral corticosteroid treatment in the U-BIOPRED study.
Stacey N Reinke, Shama Naz, Romanas Chaleckis, Hector Gallart-Ayala, Johan Kolmert, David I Broadhurst

Eur Respir J· June 2022

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Does machine learning have a role in the prediction of asthma in children?
Dimpalben Patel, Graham L Hall, David Broadhurst, Anne Smith, André Schultz

Paediatr Respir Rev· March 2022

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Sensitive and quantitative determination of short-chain fatty acids in human serum using liquid chromatography mass spectrometry.
Armaghan Shafaei, Veronica Vamathevan, Jessica Pandohee, Nathan G Lawler, David Broadhurst

Anal Bioanal Chem· October 2021

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Searching for a technology-driven acute rheumatic fever test: the START study protocol.
Anna P Ralph, Rachel Webb, Nicole J Moreland, Reuben McGregor, Anthony Bosco, David Broadhurst

BMJ Open· September 2021

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Kynurenic acid may underlie sex-specific immune responses to COVID-19.
Yuping Cai, Daniel J Kim, Takehiro Takahashi, David I Broadhurst, Hong Yan

Sci Signal· July 2021

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Data supporting development and validation of liquid chromatography tandem mass spectrometry method for the quantitative determination of bile acids in feces.
Armaghan Shafaei, Joanna Rees, Claus T Christophersen, Amanda Devine, David Broadhurst

Data Brief· June 2021

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A strategy for advancing for population-based scientific discovery using the metabolome: the establishment of the Metabolomics Society Metabolomic Epidemiology Task Group.
Jessica Lasky-Su, Rachel S Kelly, Craig E Wheelock, David Broadhurst

Metabolomics· May 2021

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Detecting Sex-Related Changes to the Metabolome of a Critically Endangered Freshwater Crayfish During the Mating Season.
Emily D Lette, Quinton F Burnham, Nathan Lawler, Pierre Horwitz, Mary C Boyce, David I Broadhurst

Front Mol Biosci· April 2021

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Early and sustained Lactobacillus plantarum probiotic therapy in critical illness: the randomised, placebo-controlled, restoration of gut microflora in critical illness trial (ROCIT).
Edward Litton, Matt Anstey, David Broadhurst, Andy Chapman, Andrew Currie

Intensive Care Med· March 2021

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Extraction and quantitative determination of bile acids in feces.
Armaghan Shafaei, Joanna Rees, Claus T Christophersen, Amanda Devine, David Broadhurst

Anal Chim Acta· March 2021

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Improvement in the Prediction of Neonatal Hypoxic-Ischemic Encephalopathy with the Integration of Umbilical Cord Metabolites and Current Clinical Makers.
Daragh S O'Boyle, Warwick B Dunn, Donna O'Neill, Jennifer A Kirwan, David I Broadhurst

J Pediatr· February 2021

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Dissemination and analysis of the quality assurance (QA) and quality control (QC) practices of LC-MS based untargeted metabolomics practitioners.
Anne M Evans, Claire O'Donovan, Mary Playdon, Chris Beecher, Richard D Beger, David Broadhurst

Metabolomics· October 2020

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Kynurenic acid underlies sex-specific immune responses to COVID-19.
Yuping Cai, Daniel J Kim, Takehiro Takahashi, David I Broadhurst, Shuangge Ma

medRxiv· September 2020

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The Global Phosphorylation Landscape of SARS-CoV-2 Infection.
Mehdi Bouhaddou, Danish Memon, Bjoern Meyer, Kris M White, Veronica V Rezelj, David J Broadhurst

Cell· August 2020

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Study protocol for the safety and efficacy of probiotic therapy on days alive and out of hospital in adult ICU patients: the multicentre, randomised, placebo-controlled Restoration Of gut microflora in Critical Illness Trial (ROCIT).
Edward Litton, Matthew Anstey, David Broadhurst, Andy R Chapman, Andrew Currie

BMJ Open· June 2020

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"notame": Workflow for Non-Targeted LC-MS Metabolic Profiling.
Anton Klåvus, Marietta Kokla, Stefania Noerman, Ville M Koistinen, Marjo Tuomainen, David Broadhurst

Metabolites· March 2020

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Migrating from partial least squares discriminant analysis to artificial neural networks: a comparison of functionally equivalent visualisation and feature contribution tools using jupyter notebooks.
Kevin M Mendez, David I Broadhurst, Stacey N Reinke

Metabolomics· January 2020

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