Publications by authors named "David Brott"

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Are Laboratory Parameter (Biomarker) Values Similar to the Healthy Volunteer Reference Range in Individuals with Diabetes.
David A Brott, Michael J Goodman, Richard P Hermann, Isobel Anderson, Alexandre Kiazand

Drug Des Devel Ther· June 2021

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Drug-induced myocardial dysfunction - recommendations for assessment in clinical and pre-clinical studies.
Ahmad Ebrahimi, Joel S Raichlen, Amy Pointon, Christer Gottfridsson, Jiefen Munley, David Brott

Expert Opin Drug Saf· March 2020

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Next-Generation DILI Biomarkers: Prioritization of Biomarkers for Qualification and Best Practices for Biospecimen Collection in Drug Development.
Sharin E Roth, Mark I Avigan, David Bourdet, David Brott, Rachel Church

Clin Pharmacol Ther· February 2020

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Are laboratory parameter (biomarker) values similar to the healthy volunteer reference range in all patient populations?
David A Brott, Michael J Goodman, Richard P Hermann, Michael Merz, Roser Calvo

Drug Des Devel Ther· February 2019

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Characterization of renal biomarkers for use in clinical trials: effect of preanalytical processing and qualification using samples from subjects with diabetes.
David A Brott, Stephen T Furlong, Scott H Adler, James W Hainer, Ramin B Arani

Drug Des Devel Ther· March 2016

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Identifying susceptibility networks for drug-induced non-immune neutropenia.
Kaushal Desai, David Brott, Xiaohua Hu, Anastasia Christianson

Int J Data Min Bioinform· September 2015

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Characterization of renal biomarkers for use in clinical trials: biomarker evaluation in healthy volunteers.
David A Brott, Scott H Adler, Ramin Arani, Susan C Lovick, Mark Pinches

Drug Des Devel Ther· November 2014

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A peripherally restricted P2Y receptor antagonist altered rat tumor incidences with no human relevance: Mode of action consistent with dopamine agonism.
David A Brott, Håkan A S Andersson, Jane Stewart, Lorna Ewart, Greg Christoph

Toxicol Rep· November 2014

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Evaluation of von Willebrand factor and von Willebrand factor propeptide in models of vascular endothelial cell activation, perturbation, and/or injury.
David A Brott, Anne Katein, Heath Thomas, Michael Lawton, Robert R Montgomery

Toxicol Pathol· June 2014

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Translation strategy for the qualification of drug-induced vascular injury biomarkers.
Kaïdre Bendjama, Silvia Guionaud, Gulfidan Aras, Nadir Arber, Lina Badimon, David Brott

Toxicol Pathol· June 2014

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An acute rat in vivo screening model to predict compounds that alter blood glucose and/or insulin regulation.
David A Brott, Melody Diamond, Pam Campbell, Andy Zuvich, Letitia Cheatham

J Pharmacol Toxicol Methods· March 2014

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Assessment of cisplatin-induced kidney injury using an integrated rodent platform.
Yafei Chen, David Brott, Wenli Luo, Eric Gangl, Harriet Kamendi

Toxicol Appl Pharmacol· May 2013

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Renal biomarker changes associated with hyaline droplet nephropathy in rats are time and potentially compound dependent.
David A Brott, Patricia Bentley, Murali V P Nadella, Dale Thurman, Jim Fikes

Toxicology· January 2013

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Inhibition of oestradiol-induced prolactin release in a dual-cannulated ovariectomized rat model by carmoxirole, a peripherally restricted dopamine agonist.
David A Brott, Jennifer L Werkheiser, Pam Campbell, Patricia Bentley, Håkan H A S Andersson

Basic Clin Pharmacol Toxicol· December 2012

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Evidence for the nitric oxide pathway as a potential mode of action in fenoldopam-induced vascular injury.
David A Brott, Rudy J Richardson, Calvert S Louden

Toxicol Pathol· August 2012

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A systems biology approach for detecting toxicity-related hotspots inside protein interaction networks.
Kaushal Desai, David Brott, Xiaohua Hu, Anastasia Christianson

J Bioinform Comput Biol· October 2011

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Combining radio telemetry and automated blood sampling: a novel approach for integrative pharmacology and toxicology studies.
Harriet W Kamendi, David A Brott, Yafei Chen, Dennis C Litwin, David J Lengel

J Pharmacol Toxicol Methods· December 2010

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Biomarkers and mechanisms of drug-induced vascular injury in non-rodents.
Calvert Louden, David Brott, Anne Katein, Thomas Kelly, Sarah Gould

Toxicol Pathol· April 2006

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