Publications by authors named "David Bryder"

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Ontogeny-specific induction of the KMT2A::AFF1-fusion drives development of a distinct CD24 positive pre-leukemic state.
Ariana S Calderón, Roshanak Ghazanfari, Zahra Masoumi, Shabnam Kharazi, Sara Palo, David Bryder

Leukemia· September 2025

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PUS10-induced tRNA fragmentation impacts retrotransposon-driven inflammation.
Magdalena Madej, Phuong Cao Thi Ngoc, Sowndarya Muthukumar, Anna Konturek-Cieśla, Silvia Tucciarone, David Bryder

Cell Rep· June 2025

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A non-genotoxic stem cell therapy boosts lymphopoiesis and averts age-related blood diseases in mice.
Anna Konturek-Ciesla, Qinyu Zhang, Shabnam Kharazi, David Bryder

Nat Commun· June 2025

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Endomucin marks quiescent long-term multi-lineage repopulating hematopoietic stem cells and is essential for their transendothelial migration.
Sophia Engelhard, Montserrat Estruch, Shuyu Qin, Christoph A Engelhard, Francisco G Rodriguez-Gonzalez, David Bryder

Cell Rep· July 2024

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A temporal developmental map separates human NK cells from noncytotoxic ILCs through clonal and single-cell analysis.
Dang Nghiem Vo, Ouyang Yuan, Minoru Kanaya, Gladys Telliam-Dushime, Hongzhe Li, David Bryder

Blood Adv· June 2024

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Revitalizing the Aging Immune System Through Selective Stem Cell Targeting.
Anna Konturek-Ciesla, David Bryder

Cell Reprogram· June 2024

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A complex interplay of intra- and extracellular factors regulates the outcome of fetal- and adult-derived MLL-rearranged leukemia.
Maria Jassinskaja, Sudip Ghosh, Joanna Watral, Mina Davoudi, Melina Claesson Stern, David Bryder

Leukemia· May 2024

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LIN28B promotes differentiation of fully transformed AML cells but is dispensable for fetal leukemia suppression.
Yanan Li, Jonny Mendoza-Castrejon, Riddhi M Patel, Emily B Casey, Elisabeth Denby, David Bryder

Leukemia· March 2024

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Ex vivo expansion potential of murine hematopoietic stem cells is a rare property only partially predicted by phenotype.
Qinyu Zhang, Rasmus Olofzon, Anna Konturek-Ciesla, Ouyang Yuan, David Bryder

Elife· March 2024

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Implications of stress-induced gene expression for hematopoietic stem cell aging studies.
Anna Konturek-Ciesla, Rasmus Olofzon, Shabnam Kharazi, David Bryder

Nat Aging· February 2024

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Ontogeny shapes the ability of ETV6::RUNX1 to enhance hematopoietic stem cell self-renewal and disrupt early lymphopoiesis.
Mohamed Eldeeb, Anna Konturek-Ciesla, Qinyu Zhang, Shabnam Kharazi, Johanna Tingvall-Gustafsson, David Bryder

Leukemia· February 2024

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Concurrent stem- and lineage-affiliated chromatin programs precede hematopoietic lineage restriction.
Fatemeh Safi, Parashar Dhapola, Sarah Warsi, Mikael Sommarin, Eva Erlandsson, David Bryder

Cell Rep· October 2023

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Temporal multimodal single-cell profiling of native hematopoiesis illuminates altered differentiation trajectories with age.
Anna Konturek-Ciesla, Parashar Dhapola, Qinyu Zhang, Petter Säwén, Haixia Wan, David Bryder

Cell Rep· April 2023

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Temporal dynamics of TNF-mediated changes in hematopoietic stem cell function and recovery.
Alexandra Rundberg Nilsson, Isabel Hidalgo, David Bryder, Cornelis Jan Pronk

iScience· April 2023

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A fetal tumor suppressor axis abrogates MLL-fusion-driven acute myeloid leukemia.
Mohamed Eldeeb, Ouyang Yuan, Nicola Guzzi, Phuong Cao Thi Ngoc, Anna Konturek-Ciesla, David Bryder

Cell Rep· February 2023

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Developmental cues license megakaryocyte priming in murine hematopoietic stem cells.
Trine A Kristiansen, Qinyu Zhang, Stefano Vergani, Elena Boldrin, Niklas Krausse, David Bryder

Blood Adv· December 2022

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A self-sustaining layer of early-life-origin B cells drives steady-state IgA responses in the adult gut.
Stefano Vergani, Konjit Getachew Muleta, Clément Da Silva, Alexander Doyle, Trine Ahn Kristiansen, David Bryder

Immunity· October 2022

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Bmi1 induction protects hematopoietic stem cells against pronounced long-term hematopoietic stress.
Isabel Hidalgo, Martin Wahlestedt, Ouyang Yuan, Qinyu Zhang, David Bryder

Exp Hematol· May 2022

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Concurrent stem- and lineage-affiliated chromatin programs precede hematopoietic lineage restriction.
Fatemeh Safi, Parashar Dhapola, Sarah Warsi, Mikael Sommarin, Eva Erlandsson, David Bryder

Cell Rep· May 2022

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Antigen-Presenting B Cells Program the Efferent Lymph T Helper Cell Response.
Samuel Alsén, Jakob Cervin, Yaxiong Deng, Louis Szeponik, Ulf Alexander Wenzel, David Bryder

Front Immunol· April 2022

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A somatic mutation in moesin drives progression into acute myeloid leukemia.
Ouyang Yuan, Amol Ugale, Tommaso de Marchi, Vimala Anthonydhason, Anna Konturek-Ciesla, David Bryder

Sci Adv· April 2022

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Stem Cells, Hematopoiesis and Lineage Tracing: Transplantation-Centric Views and Beyond.
Anna Konturek-Ciesla, David Bryder

Front Cell Dev Biol· April 2022

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Reconciling Flux Experiments for Quantitative Modeling of Normal and Malignant Hematopoietic Stem/Progenitor Dynamics.
Munetomo Takahashi, Melania Barile, Richard H Chapple, Yu-Jung Tseng, Daisuke Nakada, David Bryder

Stem Cell Reports· April 2021

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Continuous mitotic activity of primitive hematopoietic stem cells in adult mice.
Mina N F Morcos, Thomas Zerjatke, Ingmar Glauche, Clara M Munz, Yan Ge, David Bryder

J Exp Med· June 2020

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Enhancing Hematopoiesis from Murine Embryonic Stem Cells through MLL1-Induced Activation of a Rac/Rho/Integrin Signaling Axis.
Weiwei Yang, G Devon Trahan, Elizabeth D Howell, Nancy A Speck, Kenneth L Jones, David Bryder

Stem Cell Reports· February 2020

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