Publications by authors named "David C Bloom"

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Regulated microbe vaccines: from concept to (pre-clinical) reduction to practice.
Richard Voellmy, David C Bloom, Nuria Vilaboa

Expert Rev Vaccines· December 2025

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Multiple long-range interactions generate CTCF insulator-dependent viral chromatin domains in quiescent HSV-1 genomes.
Alyssa Richman, Sophie Kogut, Terri Edwards, Joseph Boyd, Princess Rodriguez, David C Bloom

mBio· October 2025

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Multiple long-range interactions generate CTCF insulator-dependent viral chromatin domains in quiescent HSV-1 genomes.
Alyssa Richman, Sophie Kogut, Terri Edwards, Joseph Boyd, Princess Rodriguez, David C Bloom

bioRxiv· May 2025

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Phosphorylated-tau associates with HSV-1 chromatin and correlates with nuclear speckles decondensation in low-density host chromatin regions.
Leonardo D'Aiuto, Jill K Caldwell, Terri G Edwards, Chaoming Zhou, Matthew L McDonald, David C Bloom

Neurobiol Dis· March 2025

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A Broad Influenza Vaccine Based on a Heat-Activated, Tissue-Restricted Replication-Competent Herpesvirus.
Nuria Vilaboa, David C Bloom, William Canty, Richard Voellmy

Vaccines (Basel)· June 2024

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Very Broadly Effective Hemagglutinin-Directed Influenza Vaccines with Anti-Herpetic Activity.
David C Bloom, Cameron Lilly, William Canty, Nuria Vilaboa, Richard Voellmy

Vaccines (Basel)· May 2024

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RNA-Seq time-course analysis of neural precursor cell transcriptome in response to herpes simplex Virus-1 infection.
Joel A Wood, Srilakshmi Chaparala, Cecilia Bantang, Ansuman Chattopadhyay, Maribeth A Wesesky, David C Bloom

J Neurovirol· April 2024

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A viral lncRNA tethers HSV-1 genomes at the nuclear periphery to establish viral latency.
Tristan R Grams, Terri G Edwards, David C Bloom

J Virol· December 2023

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Treatment of infection and inflammation associated with COVID-19, multi-drug resistant pneumonia and fungal sinusitis by nebulizing a nanosilver solution.
Patricia L Nadworny, William L Hickerson, Holly Denise Holley-Harrison, David C Bloom, Tristan R Grams

Nanomedicine· February 2023

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HSV-1 LAT Promoter Deletion Viruses Exhibit Strain-Specific and LAT-Dependent Epigenetic Regulation of Latent Viral Genomes in Human Neurons.
Tristan R Grams, Terri G Edwards, David C Bloom

J Virol· February 2023

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Truncated ring-A amaryllidaceae alkaloid modulates the host cell integrated stress response, exhibiting antiviral activity to HSV-1 and SARSCoV-2.
James McNulty, Chanti Babu-Dokuburra, Jon Scattolon, Carlos Zepeda-Velazquez, Maribeth A Wesesky, David C Bloom

Sci Rep· January 2023

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Variations in Aspects of Neural Precursor Cell Neurogenesis in a Human Model of HSV-1 Infection.
Wenxiao Zheng, Emily M Benner, David C Bloom, Vaishali Muralidaran, Jill K Caldwell

Organogenesis· December 2022

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The Impaired Neurodevelopment of Human Neural Rosettes in HSV-1-Infected Early Brain Organoids.
Leonardo D'Aiuto, Jill K Caldwell, Callen T Wallace, Tristan R Grams, Maribeth A Wesesky, David C Bloom

Cells· November 2022

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A 77 Amino Acid Region in the N-Terminal Half of the HSV-1 E3 Ubiquitin Ligase ICP0 Contributes to Counteracting an Established Type 1 Interferon Response.
Mirna Perusina Lanfranca, Jessica M van Loben Sels, Cindy Y Ly, Tristan R Grams, Adit Dhummakupt, David C Bloom

Microbiol Spectr· August 2022

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Individual and Synergistic Anti-Coronavirus Activities of SOCS1/3 Antagonist and Interferon α1 Peptides.
Chulbul M Ahmed, Tristan R Grams, David C Bloom, Howard M Johnson, Alfred S Lewin

Front Immunol· July 2022

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Antiviral activity of 1,4-disubstituted-1,2,3-triazoles against HSV-1 in vitro.
Daiane J Viegas, Verônica D da Silva, Camilla D Buarque, David C Bloom, Paula A Abreu

Antivir Ther· May 2022

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Transneuronal tracing to map connectivity in injured and transplanted spinal networks.
Tara A Fortino, Margo L Randelman, Adam A Hall, Jasbir Singh, David C Bloom

Exp Neurol· May 2022

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Signaling Pathway Reporter Screen with SARS-CoV-2 Proteins Identifies nsp5 as a Repressor of p53 Activity.
Abhishek Kumar, Tristan R Grams, David C Bloom, Zsolt Toth

Viruses· May 2022

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Deletion of the CTRL2 Insulator in HSV-1 Results in the Decreased Expression of Genes Involved in Axonal Transport and Attenuates Reactivation .
Pankaj Singh, Matthew F Collins, Richard N Johns, Kayley A Manuel, Ziyun A Ye, David C Bloom

Viruses· April 2022

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Modeling Aβ42 Accumulation in Response to Herpes Simplex Virus 1 Infection: 2D or 3D?
Eric E Abrahamson, Wenxiao Zheng, Vaishali Muralidaran, Milos D Ikonomovic, David C Bloom

J Virol· March 2021

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Herpes Simplex Virus 1 MicroRNA miR-H8 Is Dispensable for Latency and Reactivation .
Enrico R Barrozo, Sanae Nakayama, Pankaj Singh, Donna M Neumann, David C Bloom

J Virol· January 2021

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Correction for Zheng et al., "Patterns of Herpes Simplex Virus 1 Infection in Neural Progenitor Cells".
Wenxiao Zheng, Alissa M Klammer, Jennifer N Naciri, Jason Yeung, Matthew Demers, David C Bloom

J Virol· January 2021

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Herpes Simplex Virus 1 Strains 17 and KOS(M) Differ Greatly in Their Ability To Reactivate from Human Neurons .
Tristan R Grams, Terri G Edwards, David C Bloom

J Virol· July 2020

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Patterns of Herpes Simplex Virus 1 Infection in Neural Progenitor Cells.
Wenxiao Zheng, Alissa M Klammer, Jennifer N Naciri, Jason Yeung, Matthew Demers, David C Bloom

J Virol· July 2020

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Herpes Simplex Viruses Whose Replication Can Be Deliberately Controlled as Candidate Vaccines.
Richard Voellmy, David C Bloom, Nuria Vilaboa

Vaccines (Basel)· May 2020

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