Publications by authors named "David C Duffy"

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A compartmentalization-free microfluidic digital assay for detecting picogram levels of protein analytes.
Nguyen H Le, N Sathishkumar, Alinaghi Salari, Ryan Manning, Raymond E Meyer, David C Duffy

Lab Chip· June 2025

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A digital microfluidic approach to increasing sample volume and reducing bead numbers in single molecule array assays.
Alinaghi Salari, Jose Gilberto Camacho Valenzuela, Nguyen Le, Joshua Dahmer, Alexandros A Sklavounos, David C Duffy

Lab Chip· March 2025

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Improving the Accuracy, Robustness, and Dynamic Range of Digital Bead Assays.
Jianli Zhang, Alexander D Wiener, Raymond E Meyer, Cheuk W Kan, David M Rissin, David C Duffy

Anal Chem· June 2023

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Digital detection of proteins.
David C Duffy

Lab Chip· March 2023

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Ultrasensitive multiplexed chemiluminescent enzyme-linked immunosorbent assays in 384-well plates.
Tianhong Chen, Adiba Ubaidu, Scott Douglas, Samantha Carranza, Alexis Wong, David C Duffy

J Immunol Methods· September 2022

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Short Keynote Paper: Single Molecule Detection of Protein Biomarkers to Define the Continuum From Health to Disease.
David C Duffy

IEEE J Biomed Health Inform· July 2020

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Toxin A-Predominant Pathogenic Clostridioides difficile: A Novel Clinical Phenotype.
Qianyun Lin, Nira R Pollock, Alice Banz, Aude Lantz, Hua Xu, David C Duffy

Clin Infect Dis· June 2020

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Digital enzyme-linked immunosorbent assays with sub-attomolar detection limits based on low numbers of capture beads combined with high efficiency bead analysis.
Cheuk W Kan, Carmen I Tobos, David M Rissin, Alexander D Wiener, Ray E Meyer, David C Duffy

Lab Chip· June 2020

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Customizable Multiplex Antibody Array Immunoassays with Attomolar Sensitivities.
Carmen I Tobos, Antony J Sheehan, David C Duffy, David M Rissin

Anal Chem· April 2020

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Direct Detection of miR-122 in Hepatotoxicity Using Dynamic Chemical Labeling Overcomes Stability and isomiR Challenges.
Barbara López-Longarela, Emma E Morrison, John D Tranter, Lianne Chahman-Vos, Jean-François Léonard, David C Duffy

Anal Chem· February 2020

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Sensitivity and binding kinetics of an ultra-sensitive chemiluminescent enzyme-linked immunosorbent assay at arrays of antibodies.
Carmen I Tobos, Seunghyeon Kim, David M Rissin, Joseph M Johnson, Scott Douglas, David C Duffy

J Immunol Methods· November 2019

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Long-term history of vehicle collisions on the endangered Nēnē (Branta sandvicensis).
Christopher A Lepczyk, Jean E Fantle-Lepczyk, Kathleen Misajon, Darcy Hu, David C Duffy

PLoS One· October 2019

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Protein Detection by Counting Molecules.
David C Duffy, David R Walt

Clin Chem· June 2019

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Using population viability analysis to evaluate management activities for an endangered Hawaiian endemic, the Puaiohi (Myadestes palmeri).
Jean Fantle-Lepczyk, Andrew Taylor, David C Duffy, Lisa H Crampton, Sheila Conant

PLoS One· January 2019

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Availability, diversification and versatility explain human selection of introduced plants in Ecuadorian traditional medicine.
G Hart, Orou G Gaoue, Lucía de la Torre, Hugo Navarrete, Priscilla Muriel, David Cameron Duffy

PLoS One· October 2017

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Polymerase-free measurement of microRNA-122 with single base specificity using single molecule arrays: Detection of drug-induced liver injury.
David M Rissin, Barbara López-Longarela, Salvatore Pernagallo, Hugh Ilyine, A D Bastiaan Vliegenthart, David C Duffy

PLoS One· September 2017

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The Simoa HD-1 Analyzer: A Novel Fully Automated Digital Immunoassay Analyzer with Single-Molecule Sensitivity and Multiplexing.
David H Wilson, David M Rissin, Cheuk W Kan, David R Fournier, Tomasz Piech, David C Duffy

J Lab Autom· August 2016

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Development and Validation of Digital Enzyme-Linked Immunosorbent Assays for Ultrasensitive Detection and Quantification of Clostridium difficile Toxins in Stool.
Linan Song, Mingwei Zhao, David C Duffy, Joshua Hansen, Kelsey Shields

J Clin Microbiol· October 2015

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A fully-automated, six-plex single molecule immunoassay for measuring cytokines in blood.
Andrew J Rivnak, David M Rissin, Cheuk W Kan, Linan Song, Matthew W Fishburn, David C Duffy

J Immunol Methods· September 2015

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Differential immunodetection of toxin B from highly virulent Clostridium difficile BI/NAP-1/027.
Nira R Pollock, Linan Song, Mingwei Zhao, David C Duffy, Xinhua Chen

J Clin Microbiol· May 2015

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Multiplexed single molecule immunoassays.
David M Rissin, Cheuk W Kan, Linan Song, Andrew J Rivnak, Matthew W Fishburn, David C Duffy

Lab Chip· August 2013

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Tau proteins in serum predict neurological outcome after hypoxic brain injury from cardiac arrest: results of a pilot study.
Jeffrey Randall, Erik Mörtberg, Gail K Provuncher, David R Fournier, David C Duffy

Resuscitation· March 2013

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Simple diffusion-constrained immunoassay for p24 protein with the sensitivity of nucleic acid amplification for detecting acute HIV infection.
Lei Chang, Linan Song, David R Fournier, Cheuk W Kan, Purvish P Patel, David C Duffy

J Virol Methods· March 2013

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Direct detection of bacterial genomic DNA at sub-femtomolar concentrations using single molecule arrays.
Linan Song, Dandan Shan, Mingwei Zhao, Brian A Pink, Kaitlin A Minnehan, David C Duffy

Anal Chem· February 2013

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Single molecule enzyme-linked immunosorbent assays: theoretical considerations.
Lei Chang, David M Rissin, David R Fournier, Tomasz Piech, Purvish P Patel, David C Duffy

J Immunol Methods· April 2012

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