Publications by authors named "David C Harrison"

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Behaviour profile characterization of PS19 and rTg4510 tauopathy mouse models: A systematic review and a meta-analysis.
Renata L Alves, Ana Gonçalves, Iryna Voytyuk, David C Harrison

Exp Neurol· July 2025

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Discovery of : A Highly Potent, Selective, and CNS Penetrant mGluR Allosteric Agonist.
Louise Dickson, Martin Teall, Elodie Chevalier, Toni Cheung, Gemma M Liwicki, David C Harrison

ACS Med Chem Lett· April 2023

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The oDGal Mouse: A Novel, Physiologically Relevant Rodent Model of Sporadic Alzheimer's Disease.
Wayne Chadwick, Stuart Maudsley, William Hull, Enes Havolli, Eugene Boshoff, David C Harrison

Int J Mol Sci· April 2023

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Changes in the gut microbiome and fermentation products concurrent with enhanced longevity in acarbose-treated mice.
Byron J Smith, Richard A Miller, Aaron C Ericsson, David C Harrison, Randy Strong

BMC Microbiol· June 2019

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Orally bioavailable and brain-penetrant pyridazine and pyridine-derived γ-secretase modulators reduced amyloidogenic Aβ peptides in vivo.
Yunhong Huang, Ting Li, Andrew Eatherton, William L Mitchell, Na Rong, David C Harrison

Neuropharmacology· July 2013

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Γ-secretase modulators do not induce Aβ-rebound and accumulation of β-C-terminal fragment.
Ting Li, Yunhong Huang, Shiyi Jin, Liang Ye, Na Rong, David C Harrison

J Neurochem· April 2012

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Dynamics of Aβ42 reduction in plasma, CSF and brain of rats treated with the γ-secretase modulator, GSM-10h.
Julie Hawkins, David C Harrison, Sharlin Ahmed, Robert P Davis, Trevor Chapman

Neurodegener Dis· December 2011

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Pyridine-derived γ-secretase modulators.
Zehong Wan, Adrian Hall, Yingxia Sang, Jia-Ning Xiang, Eric Yang, David C Harrison

Bioorg Med Chem Lett· August 2011

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TASTPM mice expressing amyloid precursor protein and presenilin-1 mutant transgenes are sensitive to γ-secretase modulation and amyloid-β₄₂ lowering by GSM-10h.
Ishrut Hussain, David C Harrison, Julie Hawkins, Trevor Chapman, Ian Marshall

Neurodegener Dis· April 2011

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Localisation of NMU1R and NMU2R in human and rat central nervous system and effects of neuromedin-U following central administration in rats.
Jane Gartlon, Philip Szekeres, Mark Pullen, Henry M Sarau, Nambi Aiyar, David C Harrison

Psychopharmacology (Berl)· December 2004

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Quantitative analysis of gene transcription in stroke models using real-time RT-PCR.
David C Harrison, Brian C Bond

Methods Mol Med· December 2004

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Localisation of the GPRC5B receptor in the rat brain and spinal cord.
Melanie J Robbins, Kelly J Charles, David C Harrison, Menelas N Pangalos

Brain Res Mol Brain Res· October 2002

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Cloning and functional expression of a human orthologue of rat vanilloid receptor-1.
Philip Hayes, Helen J Meadows, Martin J Gunthorpe, Mark H Harries, Malcolm D Duckworth, David C Harrison

Pain· November 2000

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