Publications by authors named "David C Moebius"

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Correction to "Discovery of Nelutroctiv (CK-136), a Selective Cardiac Troponin Activator for the Treatment of Cardiovascular Diseases Associated with Reduced Cardiac Contractility".
Antonio Romero, Luke Ashcraft, Aroop Chandra, Vincent DiMassa, Peadar Cremin, David C Moebius

J Med Chem· January 2025

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Required Immunoproteasome Subunit Inhibition Profile for Anti-Inflammatory Efficacy and Clinical Candidate KZR-616 ((2 S,3 R)- N-(( S)-3-(Cyclopent-1-en-1-yl)-1-(( R)-2-methyloxiran-2-yl)-1-oxopropan-2-yl)-3-hydroxy-3-(4-methoxyphenyl)-2-(( S)-2-(2-morpholinoacetamido)propanamido)propenamide).
Henry W B Johnson, Eric Lowe, Janet L Anderl, Andrea Fan, Tony Muchamuel, David C Moebius

J Med Chem· December 2018

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Discovery of Highly Selective Inhibitors of the Immunoproteasome Low Molecular Mass Polypeptide 2 (LMP2) Subunit.
Henry W B Johnson, Janet L Anderl, Erin K Bradley, John Bui, Jeffrey Jones, David C Moebius

ACS Med Chem Lett· April 2017

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Total Synthesis of (-)-Nemorosone and (+)-Secohyperforin.
Brian A Sparling, James K Tucker, David C Moebius, Matthew D Shair

Org Lett· July 2015

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Catalysis of diazoalkane-carbonyl homologation. How new developments in hydrazone oxidation enable the carbon insertion strategy for synthesis.
David C Moebius, Victor L Rendina, Jason S Kingsbury

Top Curr Chem· March 2015

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Enantioselective total synthesis of hyperforin.
Brian A Sparling, David C Moebius, Matthew D Shair

J Am Chem Soc· January 2013

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An enantioselective synthesis of 2-aryl cycloalkanones by Sc-catalyzed carbon insertion.
Victor L Rendina, David C Moebius, Jason S Kingsbury

Org Lett· April 2011

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Catalytic and regioselective ring expansion of arylcyclobutanones with trimethylsilyldiazomethane. Ligand-dependent entry to beta-ketosilane or enolsilane adducts.
Jennifer A Dabrowski, David C Moebius, Andrew J Wommack, Anne F Kornahrens, Jason S Kingsbury

Org Lett· August 2010

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Diverse alkanones by catalytic carbon insertion into the formyl C-H bond. Concise access to the natural precursor of achyrofuran.
Andrew J Wommack, David C Moebius, Austin L Travis, Jason S Kingsbury

Org Lett· August 2009

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Catalytic homologation of cycloalkanones with substituted diazomethanes. Mild and efficient single-step access to alpha-tertiary and alpha-quaternary carbonyl compounds.
David C Moebius, Jason S Kingsbury

J Am Chem Soc· January 2009

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Enantioselective synthesis of cyclic amides and amines through mo-catalyzed asymmetric ring-closing metathesis.
Elizabeth S Sattely, G Alexander Cortez, David C Moebius, Richard R Schrock, Amir H Hoveyda

J Am Chem Soc· June 2005

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