Publications by authors named "David Courtman"

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Study of angiogenic cell therapy for progressive pulmonary arterial hypertension: intervention with repeat dosing of eNOS-enhanced EPCs: the SAPPHIRE trial.
Duncan J Stewart, Sanjay Mehta, George Chandy, Naushad Hirani, John Granton, David W Courtman

J Heart Lung Transplant· October 2025

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Single-cell microencapsulation improves lung retention of endothelial colony-forming cells after intravascular delivery and unmasks therapeutic benefit in severe pulmonary arterial hypertension.
Nicholas D Cober, Ketul R Chaudhary, Yupu Deng, Chyan-Jang Lee, Katelynn Rowe, David W Courtman

Cytotherapy· June 2025

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Atrial Fibrosis and Inflammation in Postoperative Atrial Fibrillation: Comparative Effects of Amiodarone, Colchicine, or Exosomes.
Sandrine Parent, Jennifer St Amant, Sophie Van Remortel, Saad Kahn, Ramana Vaka, David Courtman

JACC Clin Electrophysiol· June 2024

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Inactivation of the NLRP3 inflammasome mediates exosome-based prevention of atrial fibrillation.
Sandrine Parent, Ramana Vaka, Jennifer St Amant, Saad Kahn, Sophie Van Remortel, David Courtman

Theranostics· January 2024

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Metabolomics Analysis of Mesenchymal Stem Cell (MSC) Therapy in a Phase I Clinical Trial of Septic Shock: An Exploratory Study.
Mohammad M Banoei, Lauralyn A McIntyre, Duncan J Stewart, Shirley H J Mei, David Courtman

Metabolites· November 2023

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Extracellular vesicle microRNA and protein cargo profiling in three clinical-grade stem cell products reveals key functional pathways.
Ramana Vaka, Sandrine Parent, Yousef Risha, Saad Khan, David Courtman

Mol Ther Nucleic Acids· June 2023

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Prevention of atrial fibrillation after open-chest surgery with extracellular vesicle therapy.
Sandrine Parent, Ramana Vaka, Yousef Risha, Clarissa Ngo, Pushpinder Kanda, David Courtman

JCI Insight· June 2023

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Targeting extracellular vesicle delivery to the lungs by microgel encapsulation.
Nicholas D Cober, Katelynn Rowe, Yupu Deng, Ainara Benavente-Babace, David W Courtman

J Extracell Biol· June 2023

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Mesenchymal stem cell therapy and cognition in MS: Preliminary findings from a phase II clinical trial.
Jason A Berard, Mark S Freedman, Ruth Ann Marrie, James J Marriott, Harold L Atkins, David W Courtman

Mult Scler Relat Disord· May 2022

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Direct comparison of different therapeutic cell types susceptibility to inflammatory cytokines associated with COVID-19 acute lung injury.
Ramana Vaka, Saad Khan, Bin Ye, Yousef Risha, Sandrine Parent, David Courtman

Stem Cell Res Ther· January 2022

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Deterministic paracrine repair of injured myocardium using microfluidic-based cocooning of heart explant-derived cells.
Pushpinder Kanda, Ainara Benavente-Babace, Sandrine Parent, Michie Connor, Nicholas Soucy, David Courtman

Biomaterials· July 2020

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Engineering blood outgrowth endothelial cells to optimize endothelial nitric oxide synthase and extracellular matrix production for coating of blood contacting surfaces.
Yifan Yuan, Saad Khan, Duncan J Stewart, David W Courtman

Acta Biomater· June 2020

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Physiologic expansion of human heart-derived cells enhances therapeutic repair of injured myocardium.
Seth Mount, Pushpinder Kanda, Sandrine Parent, Saad Khan, Connor Michie, David Courtman

Stem Cell Res Ther· November 2019

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Deterministic Encapsulation of Human Cardiac Stem Cells in Variable Composition Nanoporous Gel Cocoons To Enhance Therapeutic Repair of Injured Myocardium.
Pushpinder Kanda, Emilio I Alarcon, Tanya Yeuchyk, Sandrine Parent, Robert A de Kemp, David Courtman

ACS Nano· May 2018

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Cellular Immunotherapy for Septic Shock. A Phase I Clinical Trial.
Lauralyn A McIntyre, Duncan J Stewart, Shirley H J Mei, David Courtman, Irene Watpool

Am J Respir Crit Care Med· February 2018

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Differentiation of Murine Bone Marrow-Derived Smooth Muscle Progenitor Cells Is Regulated by PDGF-BB and Collagen.
Clifford Lin, Yifan Yuan, David W Courtman

PLoS One· August 2017

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Marked Strain-Specific Differences in the SU5416 Rat Model of Severe Pulmonary Arterial Hypertension.
Baohua Jiang, Yupu Deng, Colin Suen, Mohamad Taha, Ketul R Chaudhary, David W Courtman

Am J Respir Cell Mol Biol· April 2016

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Endothelial NO-Synthase Gene-Enhanced Progenitor Cell Therapy for Pulmonary Arterial Hypertension: The PHACeT Trial.
John Granton, David Langleben, Michael B Kutryk, Nancy Camack, Jacques Galipeau, David W Courtman

Circ Res· September 2015

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Proteomic analysis implicates translationally controlled tumor protein as a novel mediator of occlusive vascular remodeling in pulmonary arterial hypertension.
Jessie R Lavoie, Mark L Ormiston, Carol Perez-Iratxeta, David W Courtman, Baohua Jiang

Circulation· May 2014

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The effect of encapsulation of cardiac stem cells within matrix-enriched hydrogel capsules on cell survival, post-ischemic cell retention and cardiac function.
Audrey E Mayfield, Everad L Tilokee, Nicholas Latham, Brian McNeill, Bu-Khanh Lam, David W Courtman

Biomaterials· January 2014

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Derivation of human peripheral blood derived endothelial progenitor cells and the role of osteopontin surface modification and eNOS transfection.
Yifan Yuan, Wafa A Altalhi, Jeannette J Ng, David W Courtman

Biomaterials· October 2013

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A lymphocyte-dependent mode of action for imatinib mesylate in experimental pulmonary hypertension.
Mark L Ormiston, Yupu Deng, Natalie Rundle, Farid Bendjelloul, James N Tsoporis, David W Courtman

Am J Pathol· May 2013

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Differential roles of endothelin-1 in angiotensin II-induced atherosclerosis and aortic aneurysms in apolipoprotein E-null mice.
Renée S Suen, Sarah N Rampersad, Duncan J Stewart, David W Courtman

Am J Pathol· September 2011

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The role of transglutaminase 2 and osteopontin in matrix protein supplemented microencapsulation of marrow stromal cells.
Nazanin Hakimzadeh, Duncan J Stewart, David W Courtman

Biomaterials· December 2010

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Rationale and design of Enhanced Angiogenic Cell Therapy in Acute Myocardial Infarction (ENACT-AMI): the first randomized placebo-controlled trial of enhanced progenitor cell therapy for acute myocardial infarction.
Monica Taljaard, Michael R Ward, Michael J B Kutryk, David W Courtman, Nancy J Camack

Am Heart J· March 2010

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