Publications by authors named "David D Boehr"

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Multivalent Interactions Between the Picornavirus 3C(D) Main Protease and RNA Oligonucleotides Induce Liquid-Liquid Phase Separation.
Somnath Mondal, Saumyak Mukherjee, Kevin E W Namitz, Neela H Yennawar, David D Boehr

Viruses· November 2025

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Molecular determinants of picornavirus 3C protease binding to phosphoinositide-enriched lipid membranes.
Jie Yu, Dennis S Winston, David D Boehr

J Biol Chem· September 2025

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Editorial: Allosteric functions and inhibitions: structural insights.
David D Boehr

Front Mol Biosci· January 2024

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Picornavirus 3C Proteins Intervene in Host Cell Processes through Proteolysis and Interactions with RNA.
Somnath Mondal, Gisoo Sarvari, David D Boehr

Viruses· December 2023

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Regulatory mechanisms triggered by enzyme interactions with lipid membrane surfaces.
Jie Yu, David D Boehr

Front Mol Biosci· November 2023

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Allostery, engineering and inhibition of tryptophan synthase.
Rebecca N D'Amico, David D Boehr

Curr Opin Struct Biol· October 2023

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Conformational Transitions in Yeast Chorismate Mutase Important for Allosteric Regulation as Identified by Nuclear Magnetic Resonance Spectroscopy.
Dennis S Winston, Scott D Gorman, David D Boehr

J Mol Biol· September 2022

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Catalyst-based biomolecular logic gates.
Dennis S Winston, David D Boehr

Catalysts· July 2022

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Allosteric and dynamic control of RNA-dependent RNA polymerase function and fidelity.
Dennis S Winston, David D Boehr

Enzymes· October 2021

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Substitution of a Surface-Exposed Residue Involved in an Allosteric Network Enhances Tryptophan Synthase Function in Cells.
Rebecca N D'Amico, Yuliana K Bosken, Kathleen F O'Rourke, Alec M Murray, Woudasie Admasu, David D Boehr

Front Mol Biosci· May 2021

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Distinct conformational dynamics and allosteric networks in alpha tryptophan synthase during active catalysis.
Kathleen F O'Rourke, Rebecca N D'Amico, Debashish Sahu, David D Boehr

Protein Sci· March 2021

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The Picornavirus Precursor 3CD Has Different Conformational Dynamics Compared to 3C and 3D in Functionally Relevant Regions.
Dennis S Winston, David D Boehr

Viruses· March 2021

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Driving Protein Conformational Cycles in Physiology and Disease: "Frustrated" Amino Acid Interaction Networks Define Dynamic Energy Landscapes: Amino Acid Interaction Networks Change Progressively Along Alpha Tryptophan Synthase's Catalytic Cycle.
Rebecca N D'Amico, Alec M Murray, David D Boehr

Bioessays· September 2020

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Different Solvent and Conformational Entropy Contributions to the Allosteric Activation and Inhibition Mechanisms of Yeast Chorismate Mutase.
Scott D Gorman, Dennis S Winston, Debashish Sahu, David D Boehr

Biochemistry· July 2020

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2'-C-methylated nucleotides terminate virus RNA synthesis by preventing active site closure of the viral RNA-dependent RNA polymerase.
Alyson K Boehr, Jamie J Arnold, Hyung S Oh, Craig E Cameron, David D Boehr

J Biol Chem· November 2019

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Engineering Allostery into Proteins.
Scott D Gorman, Rebecca N D'Amico, Dennis S Winston, David D Boehr

Adv Exp Med Biol· November 2019

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Energy and Enzyme Activity Landscapes of Yeast Chorismate Mutase at Cellular Concentrations of Allosteric Effectors.
Scott D Gorman, David D Boehr

Biochemistry· October 2019

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Coordinated Network Changes across the Catalytic Cycle of Alpha Tryptophan Synthase.
Kathleen F O'Rourke, Debashish Sahu, Yuliana K Bosken, Rebecca N D'Amico, Chia-En A Chang, David D Boehr

Structure· September 2019

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Rational Control of Poliovirus RNA-Dependent RNA Polymerase Fidelity by Modulating Motif-D Loop Conformational Dynamics.
Jingjing Shi, Jacob M Perryman, Xiaorong Yang, Xinran Liu, Derek M Musser, Alyson K Boehr, David D Boehr

Biochemistry· September 2019

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Millisecond Timescale Motions Connect Amino Acid Interaction Networks in Alpha Tryptophan Synthase.
Kathleen F O'Rourke, Jennifer M Axe, Rebecca N D'Amico, Debashish Sahu, David D Boehr

Front Mol Biosci· November 2018

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Assigning methyl resonances for protein solution-state NMR studies.
Scott D Gorman, Debashish Sahu, Kathleen F O'Rourke, David D Boehr

Methods· September 2018

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NMR Methods of Characterizing Biomolecular Structural Dynamics and Conformational Ensembles.
David D Boehr

Methods· September 2018

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Engineered control of enzyme structural dynamics and function.
David D Boehr, Rebecca N D'Amico, Kathleen F O'Rourke

Protein Sci· April 2018

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The RNA-Binding Site of Poliovirus 3C Protein Doubles as a Phosphoinositide-Binding Domain.
Djoshkun Shengjuler, Yan Mei Chan, Simou Sun, Ibrahim M Moustafa, Zhen-Lu Li, David D Boehr

Structure· December 2017

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Triphosphate Reorientation of the Incoming Nucleotide as a Fidelity Checkpoint in Viral RNA-dependent RNA Polymerases.
Xiaorong Yang, Xinran Liu, Derek M Musser, Ibrahim M Moustafa, Jamie J Arnold, David D Boehr

J Biol Chem· March 2017

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