Publications by authors named "David D Moore"

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FXR adapts hepatic mitochondrial function to increased substrate oxidation in patients with obesity.
Katrin Panzitt, Emilian Jungwirth, Lena E Vosko, Corina T Madreiter-Sokolowski, Tobias Madl, David D Moore

Sci Transl Med· August 2025

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Changes in the FXR-cistrome and alterations in bile acid physiology in Wilson disease.
Clavia Ruth Wooton-Kee, Hari K Yalamanchili, Islam Mohamed, Manal Hassan, Kenneth D R Setchell, David D Moore

Hepatol Commun· June 2025

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Constitutive Androstane Receptor induces Ribonucleotide Reductase-M2 expression and maintains hepatocyte ploidy in mice.
Anjana Asokakumar, Bhoomika Mathur, Anthony Chau, Bea Cronologia, Frances Alencastro, David D Moore

bioRxiv· May 2025

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The Hepatokine Orosomucoid 2 Mediates Beneficial Metabolic Effects of Bile Acids.
Sung Ho Lee, Ji Ho Suh, Mi Jeong Heo, Jong Min Choi, Yang Yang, David D Moore

Diabetes· May 2024

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Hippo-YAP/TAZ signalling coordinates adipose plasticity and energy balance by uncoupling leptin expression from fat mass.
Sungwoo Choi, Ju-Gyeong Kang, Yen T H Tran, Sun-Hye Jeong, Kun-Young Park, David D Moore

Nat Metab· May 2024

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Circadian dysfunction induces NAFLD-related human liver cancer in a mouse model.
Jennifer Padilla, Noha M Osman, Beatrice Bissig-Choisat, Sandra L Grimm, Xuan Qin, David D Moore

J Hepatol· February 2024

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Vitamin B2 enables regulation of fasting glucose availability.
Peter M Masschelin, Pradip Saha, Scott A Ochsner, Aaron R Cox, Kang Ho Kim, David D Moore

Elife· July 2023

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Aryl hydrocarbon receptor maintains hepatic mitochondrial homeostasis in mice.
Mi Jeong Heo, Ji Ho Suh, Sung Ho Lee, Kyle L Poulsen, Yu A An, David D Moore

Mol Metab· June 2023

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LRH-1 induces hepatoprotective nonessential amino acids in response to acute liver injury.
Kevin C Klatt, Elizabeth J Petviashvili, David D Moore

J Clin Invest· April 2023

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The rheumatoid arthritis drug auranofin lowers leptin levels and exerts antidiabetic effects in obese mice.
Aaron R Cox, Peter M Masschelin, Pradip K Saha, Jessica B Felix, Robert Sharp, David D Moore

Cell Metab· December 2022

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A COP1-GATA2 axis suppresses AR signaling and prostate cancer.
Tao Shen, Bingning Dong, Yanling Meng, David D Moore, Feng Yang

Proc Natl Acad Sci U S A· October 2022

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A phospholipid mimetic targeting LRH-1 ameliorates colitis.
Suzanne G Mays, Emma H D'Agostino, Autumn R Flynn, Xiangsheng Huang, Guohui Wang, David D Moore

Cell Chem Biol· July 2022

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Oleic acid is an endogenous ligand of TLX/NR2E1 that triggers hippocampal neurogenesis.
Prasanna Kandel, Fatih Semerci, Rachana Mishra, William Choi, Aleksandar Bajic, David D Moore

Proc Natl Acad Sci U S A· March 2022

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Hepatic PPARα Is Destabilized by SIRT1 Deacetylase in Undernourished Male Mice.
Ji Ho Suh, Kang Ho Kim, Margaret E Conner, David D Moore, Geoffrey A Preidis

Front Nutr· March 2022

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MAPK4 promotes triple negative breast cancer growth and reduces tumor sensitivity to PI3K blockade.
Wei Wang, Dong Han, Qinbo Cai, Tao Shen, Bingning Dong, David D Moore

Nat Commun· January 2022

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MAPK6-AKT signaling promotes tumor growth and resistance to mTOR kinase blockade.
Qinbo Cai, Wolong Zhou, Wei Wang, Bingning Dong, Dong Han, David D Moore

Sci Adv· November 2021

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Ube2i deletion in adipocytes causes lipoatrophy in mice.
Aaron R Cox, Natasha Chernis, Kang Ho Kim, Peter M Masschelin, Pradip K Saha, David D Moore

Mol Metab· June 2021

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A human liver chimeric mouse model for non-alcoholic fatty liver disease.
Beatrice Bissig-Choisat, Michele Alves-Bezerra, Barry Zorman, Scott A Ochsner, Mercedes Barzi, David D Moore

JHEP Rep· June 2021

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CAR directs T cell adaptation to bile acids in the small intestine.
Mei Lan Chen, Xiangsheng Huang, Hongtao Wang, Courtney Hegner, Yujin Liu, David D Moore

Nature· May 2021

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Vertical sleeve gastrectomy confers metabolic improvements by reducing intestinal bile acids and lipid absorption in mice.
Lili Ding, Eryun Zhang, Qiaoling Yang, Lihua Jin, Kyle M Sousa, David D Moore

Proc Natl Acad Sci U S A· February 2021

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MAPK4 promotes prostate cancer by concerted activation of androgen receptor and AKT.
Tao Shen, Wei Wang, Wolong Zhou, Ilsa Coleman, Qinbo Cai, David D Moore

J Clin Invest· February 2021

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The bile acid induced hepatokine orosomucoid suppresses adipocyte differentiation.
Sung Ho Lee, Jong Min Choi, Sung Yun Jung, Aaron R Cox, Sean M Hartig, David D Moore

Biochem Biophys Res Commun· January 2021

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Coagulopathy in Malnourished Mice Is Sexually Dimorphic and Regulated by Nutrient-Sensing Nuclear Receptors.
Geoffrey A Preidis, Krishnakant G Soni, Ji Ho Suh, Tripti Halder, Kang Ho Kim, David D Moore

Hepatol Commun· December 2020

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NR1H4-related Progressive Familial Intrahepatic Cholestasis 5: Further Evidence for Rapidly Progressive Liver Failure.
Ryan W Himes, Majid Mojarrad, Atieh Eslahi, Milton J Finegold, Reza Maroofian, David D Moore

J Pediatr Gastroenterol Nutr· June 2020

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Eating Pattern and Nutritional Risks among People with Multiple Sclerosis Following a Modified Paleolithic Diet.
Tyler J Titcomb, Babita Bisht, David D Moore, Yashpal S Chhonker, Daryl J Murry

Nutrients· June 2020

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