Publications by authors named "David Dawbarn"

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Design and nuclear magnetic resonance (NMR) structure determination of the second extracellular immunoglobulin tyrosine kinase A (TrkAIg2) domain construct for binding site elucidation in drug discovery.
Debbie K Shoemark, Christopher Williams, Mark S Fahey, Judy J Watson, Sue J Tyler, David Dawbarn

J Med Chem· January 2015

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The neurotrophins and their role in Alzheimer's disease.
Shelley J Allen, Judy J Watson, David Dawbarn

Curr Neuropharmacol· December 2011

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Neurotrophin-3 is a novel angiogenic factor capable of therapeutic neovascularization in a mouse model of limb ischemia.
Brunella Cristofaro, Oliver A Stone, Andrea Caporali, David Dawbarn, Nicholas Ieronimakis

Arterioscler Thromb Vasc Biol· June 2010

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Treatment of murine osteoarthritis with TrkAd5 reveals a pivotal role for nerve growth factor in non-inflammatory joint pain.
Kay E McNamee, Annika Burleigh, Luke L Gompels, Marc Feldmann, Shelley J Allen, David Dawbarn

Pain· May 2010

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Biological activity of nerve growth factor precursor is dependent upon relative levels of its receptors.
Raheleh Masoudi, Maria S Ioannou, Michael D Coughlin, Promila Pagadala, Kenneth E Neet, David Dawbarn

J Biol Chem· July 2009

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Brain-derived neurotrophic factor drives the changes in excitatory synaptic transmission in the rat superficial dorsal horn that follow sciatic nerve injury.
Van B Lu, James E Biggs, Martin J Stebbing, Sridhar Balasubramanyan, Kathryn G Todd, David Dawbarn

J Physiol· March 2009

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Targeting nerve growth factor in pain: what is the therapeutic potential?
Judy J Watson, Shelley J Allen, David Dawbarn

BioDrugs· January 2009

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Human ProNGF: biological effects and binding profiles at TrkA, P75NTR and sortilin.
Oliver Clewes, Mark S Fahey, Sue J Tyler, Judy J Watson, Heon Seok, David Dawbarn

J Neurochem· November 2008

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Familial Alzheimer's disease presenilin 1 mutation M146V increases gamma secretase cutting of p75NTR in vitro.
Caroline Sara Hatchett, Sue Tyler, Dawn Armstrong, David Dawbarn, Shelley Jane Allen

Brain Res· May 2007

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Pulmonary distribution, regulation, and functional role of Trk receptors in a murine model of asthma.
Christina Nassenstein, David Dawbarn, Kenneth Pollock, Shelley Jane Allen, Veit Johannes Erpenbeck

J Allergy Clin Immunol· September 2006

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Premorbid effects of APOE on synaptic proteins in human temporal neocortex.
Seth Love, L Khai Siew, David Dawbarn, Gordon K Wilcock, Yoav Ben-Shlomo

Neurobiol Aging· June 2006

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TrkAd5: A novel therapeutic agent for treatment of inflammatory pain and asthma.
Judy J Watson, Mark S Fahey, Edwin van den Worm, Ferdi Engels, Frans P Nijkamp, David Dawbarn

J Pharmacol Exp Ther· March 2006

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Clinical relevance of the neurotrophins and their receptors.
Shelley J Allen, David Dawbarn

Clin Sci (Lond)· February 2006

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Decrease in bladder overactivity with REN1820 in rats with cyclophosphamide induced cystitis.
Vivian Y Hu, Peter Zvara, Abbey Dattilio, Travis L Redman, Shelley J Allen, David Dawbarn

J Urol· March 2005

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Measurement of pre- and post-synaptic proteins in cerebral cortex: effects of post-mortem delay.
Lai Khai Siew, Seth Love, David Dawbarn, Gordon Keith Wilcock, Shelley Jane Allen

J Neurosci Methods· October 2004

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alpha- and beta-secretase: profound changes in Alzheimer's disease.
Susan J Tyler, David Dawbarn, Gordon K Wilcock, Shelley J Allen

Biochem Biophys Res Commun· December 2002

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A discrete domain of the human TrkB receptor defines the binding sites for BDNF and NT-4.
Ruth L Naylor, Alan G S Robertson, Shelley J Allen, Richard B Sessions, Anthony R Clarke, David Dawbarn

Biochem Biophys Res Commun· March 2002

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