Publications by authors named "David Dranow"

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Crystal structure of a complete threonyl tRNA synthetase: toggle clamp model?
Truc Q Tran, Michael K Fenwick, Thomas E Edwards, David M Dranow, Jan Abendroth

Biochem Biophys Res Commun· October 2025

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Architecture of glutamyl-tRNA synthetase defines a subfamily of dimeric class Ib aminoacyl-tRNA synthetases.
Michael K Fenwick, Stephen J Mayclin, Steve Seibold, Amy E DeRocher, Sandhya Subramanian, David M Dranow

Proc Natl Acad Sci U S A· May 2025

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The crystal structures of apo and tryptophan-bound tryptophanyl-tRNA synthetase from Neisseria gonorrhoeae.
Jessika Baral, David Song, Thomas E Edwards, David M Dranow, Donald D Lorimer

Acta Crystallogr F Struct Biol Commun· April 2025

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Analysis of Burkholderia pseudomallei IspF in complex with sulfapyridine, sulfamonomethoxine, ethoxzolamide and acetazolamide.
Dakota Grote, Christopher G Stewart, Drashti G Daraji, Parisa Enayati, Kristina N Braverman, David M Dranow

Acta Crystallogr F Struct Biol Commun· April 2025

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Crystal structure of dihydroorotate dehydrogenase from Helicobacter pylori with bound flavin mononucleotide.
Ashna A Agarwal, John D Georgiades, David M Dranow, Donald D Lorimer, Thomas Edwards

Acta Crystallogr F Struct Biol Commun· March 2025

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Co-crystal structure of Helicobacter pylori biotin protein ligase with biotinyl-5-ATP.
Jesuferanmi P Ayanlade, Dylan E Davis, Sandhya Subramanian, David M Dranow, Donald D Lorimer

Acta Crystallogr F Struct Biol Commun· January 2025

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Crystal structure of glutamyl-tRNA synthetase from Helicobacter pylori.
Dylan E Davis, Jesuferanmi P Ayanlade, David T Laseinde, Sandhya Subramanian, Hannah Udell, David M Dranow

Acta Crystallogr F Struct Biol Commun· December 2024

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Exquisite selectivity of griselimycin extends to beta subunit of DNA polymerases from Gram-negative bacterial pathogens.
Michael K Fenwick, Phillip G Pierce, Jan Abendroth, Kayleigh F Barrett, Lynn K Barrett, David M Dranow

Commun Biol· December 2024

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Ternary structure of Plasmodium vivaxN-myristoyltransferase with myristoyl-CoA and inhibitor IMP-0001173.
Cydni Bolling, Alex Mendez, Shane Taylor, Stanley Makumire, Alexandra Reers, David M Dranow

Acta Crystallogr F Struct Biol Commun· October 2024

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Crystal structure and biophysical characterization of IspD from Burkholderia thailandensis and Mycobacterium paratuberculosis.
Phillip G Pierce, Brian E Hartnett, Tosha M Laughlin, Joy M Blain, Stephen J Mayclin, David M Dranow

Acta Crystallogr F Struct Biol Commun· February 2024

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Characterization of an Monofunctional Phosphomethylpyrimidine Kinase That Is Inhibited by Pyridoxal Phosphate.
Humberto De Vitto, Kafi K J Belfon, Nandini Sharma, Sarah Toay, Jan Abendroth, David M Dranow

Biochemistry· February 2024

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Molecular mechanism for strengthening E-cadherin adhesion using a monoclonal antibody.
Bin Xie, Allison Maker, Andrew V Priest, David M Dranow, Jenny N Phan

Proc Natl Acad Sci U S A· August 2022

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Crystal structures of glutamyl-tRNA synthetase from Elizabethkingia anopheles and E. meningosepticum.
Lauryn Brooks, Sandhya Subramanian, David M Dranow, Stephen J Mayclin, Peter J Myler

Acta Crystallogr F Struct Biol Commun· August 2022

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Broad-spectrum in vitro activity of macrophage infectivity potentiator inhibitors against Gram-negative bacteria and Leishmania major.
Jua Iwasaki, Donald D Lorimer, Mirella Vivoli-Vega, Emily A Kibble, Christopher S Peacock, David M Dranow

J Antimicrob Chemother· May 2022

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Crystal structure of betaine aldehyde dehydrogenase from Burkholderia pseudomallei.
Dylan K Beard, Sandhya Subramanian, Jan Abendroth, David M Dranow, Thomas E Edwards

Acta Crystallogr F Struct Biol Commun· February 2022

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Crystal structures of FolM alternative dihydrofolate reductase 1 from Brucella suis and Brucella canis.
Imani Porter, Trinity Neal, Zion Walker, Dylan Hayes, Kayla Fowler, David M Dranow

Acta Crystallogr F Struct Biol Commun· January 2022

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Naegleria fowleri: Protein structures to facilitate drug discovery for the deadly, pathogenic free-living amoeba.
Logan Tillery, Kayleigh Barrett, Jenna Goldstein, Jared W Lassner, Bram Osterhout, David M Dranow

PLoS One· August 2021

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Evolutionary Diversification of Host-Targeted Effectors Proteins Derived from a Conserved FicTA Toxin-Antitoxin Module.
Tilman Schirmer, Tjaart A P de Beer, Stefanie Tamegger, Alexander Harms, Nikolaus Dietz, David M Dranow

Microorganisms· July 2021

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Structural characterization of a Type B chloramphenicol acetyltransferase from the emerging pathogen Elizabethkingia anophelis NUHP1.
Seyed Mohammad Ghafoori, Alyssa M Robles, Angelika M Arada, Paniz Shirmast, David M Dranow

Sci Rep· May 2021

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Pyrazole-Based Lactate Dehydrogenase Inhibitors with Optimized Cell Activity and Pharmacokinetic Properties.
Ganesha Rai, Daniel J Urban, Bryan T Mott, Xin Hu, Shyh-Ming Yang, David M Dranow

J Med Chem· October 2020

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Discovery of Adamantane Carboxamides as Ebola Virus Cell Entry and Glycoprotein Inhibitors.
Michael B Plewe, Nadezda V Sokolova, Vidyasagar Reddy Gantla, Eric R Brown, Shibani Naik, David M Dranow

ACS Med Chem Lett· June 2020

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Glutaminyl-tRNA Synthetase from Pseudomonas aeruginosa: Characterization, structure, and development as a screening platform.
Yaritza Escamilla, Casey A Hughes, Jan Abendroth, David M Dranow, Samantha Balboa

Protein Sci· April 2020

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Structures of glyceraldehyde 3-phosphate dehydrogenase in Neisseria gonorrhoeae and Chlamydia trachomatis.
Kayleigh F Barrett, David M Dranow, Isabelle Q Phan, Samantha A Michaels, Shareef Shaheen

Protein Sci· March 2020

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Toward a structome of Acinetobacter baumannii drug targets.
Logan M Tillery, Kayleigh F Barrett, David M Dranow, Justin Craig, Roger Shek

Protein Sci· March 2020

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Lysyl-tRNA synthetase as a drug target in malaria and cryptosporidiosis.
Beatriz Baragaña, Barbara Forte, Ryan Choi, Stephen Nakazawa Hewitt, Juan A Bueren-Calabuig, David M Dranow

Proc Natl Acad Sci U S A· April 2019

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