Publications by authors named "Donald D Lorimer"

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Architecture of glutamyl-tRNA synthetase defines a subfamily of dimeric class Ib aminoacyl-tRNA synthetases.
Michael K Fenwick, Stephen J Mayclin, Steve Seibold, Amy E DeRocher, Sandhya Subramanian, Donald D Lorimer

Proc Natl Acad Sci U S A· May 2025

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Structural and kinetic analysis of distinct active and inactive states of Burkholderia cenocepacia orotate phosphoribosyltransferase.
Nandini Sharma, Zachary R Turlington, Sean P Zupko, Michael N Catoggio, Christine M Lukacs, Donald D Lorimer

Arch Biochem Biophys· April 2025

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The crystal structures of apo and tryptophan-bound tryptophanyl-tRNA synthetase from Neisseria gonorrhoeae.
Jessika Baral, David Song, Thomas E Edwards, David M Dranow, Donald D Lorimer

Acta Crystallogr F Struct Biol Commun· April 2025

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Analysis of Burkholderia pseudomallei IspF in complex with sulfapyridine, sulfamonomethoxine, ethoxzolamide and acetazolamide.
Dakota Grote, Christopher G Stewart, Drashti G Daraji, Parisa Enayati, Kristina N Braverman, Donald D Lorimer

Acta Crystallogr F Struct Biol Commun· April 2025

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Crystal structure of the S-adenosylmethionine-dependent mycolic acid synthase UmaA from Mycobacterium tuberculosis.
Sean Teng, Jie Wang, Collin D Sroge, Jan Abendroth, Donald D Lorimer

Acta Crystallogr F Struct Biol Commun· April 2025

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Structural characterization of dUTPase from Legionella pneumophila.
Chi L Nguyen, Abigail R Tramell, Jordan O Norman, Jan Abendroth, Kayleigh F Barrett, Donald D Lorimer

Acta Crystallogr F Struct Biol Commun· April 2025

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Structures of Legionella pneumophila serogroup 1 peptide deformylase bound to nickel(II) and actinonin.
Chi L Nguyen, William Fan, Sean Fisher, Krystal Matthews, Jordan O Norman, Donald D Lorimer

Acta Crystallogr F Struct Biol Commun· April 2025

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Crystal structure of dihydroorotate dehydrogenase from Helicobacter pylori with bound flavin mononucleotide.
Ashna A Agarwal, John D Georgiades, David M Dranow, Donald D Lorimer, Thomas Edwards

Acta Crystallogr F Struct Biol Commun· March 2025

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Structure of Plasmodium vivaxN-myristoyltransferase with inhibitor IMP-1088: exploring an NMT inhibitor for antimalarial therapy.
Alex Mendez, Cydni Bolling, Shane Taylor, Stanley Makumire, Bart Staker, Donald D Lorimer

Acta Crystallogr F Struct Biol Commun· January 2025

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Co-crystal structure of Helicobacter pylori biotin protein ligase with biotinyl-5-ATP.
Jesuferanmi P Ayanlade, Dylan E Davis, Sandhya Subramanian, David M Dranow, Donald D Lorimer

Acta Crystallogr F Struct Biol Commun· January 2025

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Exquisite selectivity of griselimycin extends to beta subunit of DNA polymerases from Gram-negative bacterial pathogens.
Michael K Fenwick, Phillip G Pierce, Jan Abendroth, Kayleigh F Barrett, Lynn K Barrett, Donald D Lorimer

Commun Biol· December 2024

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Structural and functional characterization of FabG4 from Mycolicibacterium smegmatis.
Xinping Ran, Prashit Parikh, Jan Abendroth, Tracy L Arakaki, Matthew C Clifton, Donald D Lorimer

Acta Crystallogr F Struct Biol Commun· April 2024

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Crystal structure and biophysical characterization of IspD from Burkholderia thailandensis and Mycobacterium paratuberculosis.
Phillip G Pierce, Brian E Hartnett, Tosha M Laughlin, Joy M Blain, Stephen J Mayclin, Donald D Lorimer

Acta Crystallogr F Struct Biol Commun· February 2024

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Characterization of a family I inorganic pyrophosphatase from Legionella pneumophila Philadelphia 1.
Julia Moorefield, Yagmur Konuk, Jordan O Norman, Jan Abendroth, Thomas E Edwards, Donald D Lorimer

Acta Crystallogr F Struct Biol Commun· October 2023

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Structural characterisation of hemagglutinin from seven Influenza A H1N1 strains reveal diversity in the C05 antibody recognition site.
Seyed Mohammad Ghafoori, Gayle F Petersen, Deborah G Conrady, Brandy M Calhoun, Matthew Z Z Stigliano, Donald D Lorimer

Sci Rep· April 2023

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Discovery and Characterization of Potent, Efficacious, Orally Available Antimalarial Plasmepsin X Inhibitors and Preclinical Safety Assessment of .
Martin A Lowe, Alvaro Cardenas, Jean-Pierre Valentin, Zhaoning Zhu, Jan Abendroth, Donald D Lorimer

J Med Chem· October 2022

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Broad-spectrum in vitro activity of macrophage infectivity potentiator inhibitors against Gram-negative bacteria and Leishmania major.
Jua Iwasaki, Donald D Lorimer, Mirella Vivoli-Vega, Emily A Kibble, Christopher S Peacock

J Antimicrob Chemother· May 2022

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Structures of plasmepsin X from Plasmodium falciparum reveal a novel inactivation mechanism of the zymogen and molecular basis for binding of inhibitors in mature enzyme.
Pooja Kesari, Anuradha Deshmukh, Nikhil Pahelkar, Abhishek B Suryawanshi, Ishan Rathore, Donald D Lorimer

Protein Sci· April 2022

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Naegleria fowleri: Protein structures to facilitate drug discovery for the deadly, pathogenic free-living amoeba.
Logan Tillery, Kayleigh Barrett, Jenna Goldstein, Jared W Lassner, Bram Osterhout, Donald D Lorimer

PLoS One· August 2021

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Structural characterization of a Type B chloramphenicol acetyltransferase from the emerging pathogen Elizabethkingia anophelis NUHP1.
Seyed Mohammad Ghafoori, Alyssa M Robles, Angelika M Arada, Paniz Shirmast, David M Dranow, Donald D Lorimer

Sci Rep· May 2021

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Crystal structure of acetoacetyl-CoA reductase from Rickettsia felis.
Justas V Rodarte, Jan Abendroth, Thomas E Edwards, Donald D Lorimer, Bart L Staker

Acta Crystallogr F Struct Biol Commun· February 2021

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Discovery of Adamantane Carboxamides as Ebola Virus Cell Entry and Glycoprotein Inhibitors.
Michael B Plewe, Nadezda V Sokolova, Vidyasagar Reddy Gantla, Eric R Brown, Shibani Naik, Donald D Lorimer

ACS Med Chem Lett· June 2020

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Structures of glyceraldehyde 3-phosphate dehydrogenase in Neisseria gonorrhoeae and Chlamydia trachomatis.
Kayleigh F Barrett, David M Dranow, Isabelle Q Phan, Samantha A Michaels, Shareef Shaheen, Donald D Lorimer

Protein Sci· March 2020

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Toward a structome of Acinetobacter baumannii drug targets.
Logan M Tillery, Kayleigh F Barrett, David M Dranow, Justin Craig, Roger Shek, Donald D Lorimer

Protein Sci· March 2020

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Lysyl-tRNA synthetase as a drug target in malaria and cryptosporidiosis.
Beatriz Baragaña, Barbara Forte, Ryan Choi, Stephen Nakazawa Hewitt, Juan A Bueren-Calabuig, Donald D Lorimer

Proc Natl Acad Sci U S A· April 2019

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