Publications by authors named "David Engelmann"

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LncRNA-SLC16A1-AS1 induces metabolic reprogramming during Bladder Cancer progression as target and co-activator of E2F1.
Stella Logotheti, Stephan Marquardt, Shailendra K Gupta, Christin Richter, Berdien A H Edelhäuser, David Engelmann

Theranostics· May 2021

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Drug Repositioning Inferred from E2F1-Coregulator Interactions Studies for the Prevention and Treatment of Metastatic Cancers.
Deborah Goody, Shailendra K Gupta, David Engelmann, Alf Spitschak, Stephan Marquardt

Theranostics· January 2020

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DNp73-induced degradation of tyrosinase links depigmentation with EMT-driven melanoma progression.
Katharina Fürst, Marc Steder, Stella Logotheti, Alessandro Angerilli, Alf Spitschak, David Engelmann

Cancer Lett· February 2019

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Unraveling a tumor type-specific regulatory core underlying E2F1-mediated epithelial-mesenchymal transition to predict receptor protein signatures.
Faiz M Khan, Stephan Marquardt, Shailendra K Gupta, Susanne Knoll, Ulf Schmitz, David Engelmann

Nat Commun· August 2017

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MiR-182 promotes cancer invasion by linking RET oncogene activated NF-κB to loss of the HES1/Notch1 regulatory circuit.
Alf Spitschak, Claudia Meier, Bhavani Kowtharapu, David Engelmann, Brigitte M Pützer

Mol Cancer· January 2017

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Integrated Loss of miR-1/miR-101/miR-204 Discriminates Metastatic from Nonmetastatic Penile Carcinomas and Can Predict Patient Outcome.
Juliane M Hartz, David Engelmann, Katharina Fürst, Stephan Marquardt, Alf Spitschak

J Urol· August 2016

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Epigenetic factor EPC1 is a master regulator of DNA damage response by interacting with E2F1 to silence death and activate metastasis-related gene signatures.
Yajie Wang, Vijay Alla, Deborah Goody, Shailendra K Gupta, Alf Spitschak, David Engelmann

Nucleic Acids Res· January 2016

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Comprehensive genomic profiles of small cell lung cancer.
Julie George, Jing Shan Lim, Se Jin Jang, Yupeng Cun, Luka Ozretić, David Engelmann

Nature· August 2015

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Emerging from the shade of p53 mutants: N-terminally truncated variants of the p53 family in EMT signaling and cancer progression.
David Engelmann, Brigitte M Pützer

Sci Signal· September 2014

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Hybrid modeling of the crosstalk between signaling and transcriptional networks using ordinary differential equations and multi-valued logic.
Faiz M Khan, Ulf Schmitz, Svetoslav Nikolov, David Engelmann, Brigitte M Pützer

Biochim Biophys Acta· January 2014

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E2F1 promotes angiogenesis through the VEGF-C/VEGFR-3 axis in a feedback loop for cooperative induction of PDGF-B.
David Engelmann, Deborah Mayoli-Nüssle, Christian Mayrhofer, Katharina Fürst, Vijay Alla

J Mol Cell Biol· December 2013

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DNp73 exerts function in metastasis initiation by disconnecting the inhibitory role of EPLIN on IGF1R-AKT/STAT3 signaling.
Marc Steder, Vijay Alla, Claudia Meier, Alf Spitschak, Jens Pahnke, David Engelmann

Cancer Cell· October 2013

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Kinetic modeling-based detection of genetic signatures that provide chemoresistance via the E2F1-p73/DNp73-miR-205 network.
Julio Vera, Ulf Schmitz, Xin Lai, David Engelmann, Faiz M Khan

Cancer Res· June 2013

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E2F1 apoptosis counterattacked: evil strikes back.
Brigitte M Pützer, David Engelmann

Trends Mol Med· February 2013

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E2F1 confers anticancer drug resistance by targeting ABC transporter family members and Bcl-2 via the p73/DNp73-miR-205 circuitry.
Vijay Alla, Bhavani S Kowtharapu, David Engelmann, Stephan Emmrich, Ulf Schmitz

Cell Cycle· August 2012

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The dark side of E2F1: in transit beyond apoptosis.
David Engelmann, Brigitte M Pützer

Cancer Res· February 2012

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Translating DNA damage into cancer cell death-A roadmap for E2F1 apoptotic signalling and opportunities for new drug combinations to overcome chemoresistance.
David Engelmann, Brigitte M Pützer

Drug Resist Updat· January 2011

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Functional interplay between E2F1 and chemotherapeutic drugs defines immediate E2F1 target genes crucial for cancer cell death.
David Engelmann, Susanne Knoll, Daniel Ewerth, Marc Steder, Anja Stoll

Cell Mol Life Sci· March 2010

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E2F1 in melanoma progression and metastasis.
Vijay Alla, David Engelmann, Annett Niemetz, Jens Pahnke, Anke Schmidt

J Natl Cancer Inst· January 2010

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Direct stimulatory effects of the TLR2/6 ligand bacterial lipopeptide MALP-2 on neutrophil granulocytes.
Inga Wilde, Sonja Lotz, David Engelmann, Andrea Starke, Ger van Zandbergen

Med Microbiol Immunol· June 2007

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