Publications by authors named "David F Stern"

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Treatment scheduling effects on the evolution of drug resistance in heterogeneous cancer cell populations.
Gauri A Patwardhan, Michal Marczyk, Vikram B Wali, David F Stern, Lajos Pusztai

NPJ Breast Cancer· May 2021

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Identifying modules of cooperating cancer drivers.
Michael I Klein, Vincent L Cannataro, Jeffrey P Townsend, Scott Newman, David F Stern

Mol Syst Biol· March 2021

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Acquired Resistance to HER2-Targeted Therapies Creates Vulnerability to ATP Synthase Inhibition.
Molly Gale, Yao Li, Jian Cao, Zongzhi Z Liu, Marissa A Holmbeck, David F Stern

Cancer Res· February 2020

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Combinatorial drug screening of mammary cells with induced mesenchymal transformation to identify drug combinations for triple-negative breast cancer.
Sierra A Colavito, James T Platt, Matthew A Held, Zongzhi Liu, Ryan Sokup, David F Stern

Oncotarget· August 2019

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Inhibition of isoprenylation synergizes with MAPK blockade to prevent growth in treatment-resistant melanoma, colorectal, and lung cancer.
Nicholas Theodosakis, Casey G Langdon, Goran Micevic, Irina Krykbaeva, Robert E Means, David F Stern

Pigment Cell Melanoma Res· March 2019

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Keeping Tumors Out of the MAPK Fitness Zone.
David F Stern

Cancer Discov· January 2018

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p90RSK Blockade Inhibits Dual BRAF and MEK Inhibitor-Resistant Melanoma by Targeting Protein Synthesis.
Nicholas Theodosakis, Goran Micevic, Casey G Langdon, Alessandra Ventura, Robert Means, David F Stern

J Invest Dermatol· October 2017

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Combinatorial Screening of Pancreatic Adenocarcinoma Reveals Sensitivity to Drug Combinations Including Bromodomain Inhibitor Plus Neddylation Inhibitor.
Casey G Langdon, James T Platt, Robert E Means, Pinar Iyidogan, Ramanaiah Mamillapalli, David F Stern

Mol Cancer Ther· June 2017

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GRAPE: a pathway template method to characterize tissue-specific functionality from gene expression profiles.
Michael I Klein, David F Stern, Hongyu Zhao

BMC Bioinformatics· June 2017

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Systematic Drug Screening Identifies Tractable Targeted Combination Therapies in Triple-Negative Breast Cancer.
Vikram B Wali, Casey G Langdon, Matthew A Held, James T Platt, Gauri A Patwardhan, David F Stern

Cancer Res· January 2017

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A Computational Approach for Identifying Synergistic Drug Combinations.
Kaitlyn M Gayvert, Omar Aly, James Platt, Marcus W Bosenberg, David F Stern

PLoS Comput Biol· January 2017

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Transcriptional Profiles from Paired Normal Samples Offer Complementary Information on Cancer Patient Survival--Evidence from TCGA Pan-Cancer Data.
Xiu Huang, David F Stern, Hongyu Zhao

Sci Rep· February 2016

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PMCA2 regulates HER2 protein kinase localization and signaling and promotes HER2-mediated breast cancer.
Jaekwang Jeong, Joshua N VanHouten, Pamela Dann, Wonnam Kim, Catherine Sullivan, David F Stern

Proc Natl Acad Sci U S A· January 2016

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SMAC mimetic Debio 1143 synergizes with taxanes, topoisomerase inhibitors and bromodomain inhibitors to impede growth of lung adenocarcinoma cells.
Casey G Langdon, Norbert Wiedemann, Matthew A Held, Ramanaiah Mamillapalli, Pinar Iyidogan, David F Stern

Oncotarget· November 2015

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Neuregulin-activated ERBB4 induces the SREBP-2 cholesterol biosynthetic pathway and increases low-density lipoprotein uptake.
Jonathan W Haskins, Shannon Zhang, Robert E Means, Joanne K Kelleher, Gary W Cline, David F Stern

Sci Signal· November 2015

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The broad-spectrum receptor tyrosine kinase inhibitor dovitinib suppresses growth of BRAF-mutant melanoma cells in combination with other signaling pathway inhibitors.
Casey G Langdon, Matthew A Held, James T Platt, Katrina Meeth, Pinar Iyidogan, David F Stern

Pigment Cell Melanoma Res· July 2015

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BRAF Inhibition Decreases Cellular Glucose Uptake in Melanoma in Association with Reduction in Cell Volume.
Nicholas Theodosakis, Matthew A Held, Alexander Marzuka-Alcala, Katrina M Meeth, Goran Micevic, David F Stern

Mol Cancer Ther· July 2015

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PDK1 and SGK3 Contribute to the Growth of BRAF-Mutant Melanomas and Are Potential Therapeutic Targets.
Marzia Scortegagna, Eric Lau, Tongwu Zhang, Yongmei Feng, Chris Sereduk, David F Stern

Cancer Res· April 2015

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Neuregulin 1-activated ERBB4 interacts with YAP to induce Hippo pathway target genes and promote cell migration.
Jonathan W Haskins, Don X Nguyen, David F Stern

Sci Signal· December 2014

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Overexpression of ERBB4 JM-a CYT-1 and CYT-2 isoforms in transgenic mice reveals isoform-specific roles in mammary gland development and carcinogenesis.
Vikram B Wali, Maureen Gilmore-Hebert, Ramanaiah Mamillapalli, Jonathan W Haskins, Kari J Kurppa, David F Stern

Breast Cancer Res· December 2014

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Comparison of HER2 and phospho-HER2 expression between biopsy and resected breast cancer specimens using a quantitative assessment method.
Yalai Bai, Huan Cheng, Jennifer Bordeaux, Veronique Neumeister, Sudha Kumar, David F Stern

PLoS One· September 2014

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Significance of glioma-associated oncogene homolog 1 (GLI1) expression in claudin-low breast cancer and crosstalk with the nuclear factor kappa-light-chain-enhancer of activated B cells (NFκB) pathway.
Sierra A Colavito, Mike R Zou, Qin Yan, Don X Nguyen, David F Stern

Breast Cancer Res· September 2014

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Convergent and divergent cellular responses by ErbB4 isoforms in mammary epithelial cells.
Vikram B Wali, Jonathan W Haskins, Maureen Gilmore-Hebert, James T Platt, Zongzhi Liu, David F Stern

Mol Cancer Res· August 2014

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EGF receptor activates MET through MAPK to enhance non-small cell lung carcinoma invasion and brain metastasis.
Jerrica L Breindel, Jonathan W Haskins, Elizabeth P Cowell, Minghui Zhao, Don X Nguyen, David F Stern

Cancer Res· August 2013

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MERTK controls melanoma cell migration and survival and differentially regulates cell behavior relative to AXL.
Kathryn A Tworkoski, James T Platt, Antonella Bacchiocchi, Marcus Bosenberg, Titus J Boggon, David F Stern

Pigment Cell Melanoma Res· July 2013

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