Publications by authors named "David Fargo"

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Implementing secondary findings analysis in a genetic and environmental research study.
Jennifer J Johnston, Julie C Sapp, Seeley Yoo, Zara Wermers, Sophia Hernandez, David Fargo

Genet Med· September 2025

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A review of geospatial exposure models and approaches for health data integration.
Lara P Clark, Daniel Zilber, Charles Schmitt, David C Fargo, David M Reif

J Expo Sci Environ Epidemiol· April 2025

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A multi-ancestry genome-wide association study identifies novel candidate loci in the RARB gene associated with hypertensive disorders of pregnancy.
Jasmine A Mack, Adam Burkholder, Farida S Akhtari, John S House, Ulla Sovio, David C Fargo

HGG Adv· January 2025

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Gene-environment interactions within a precision environmental health framework.
Alison A Motsinger-Reif, David M Reif, Farida S Akhtari, John S House, C Ryan Campbell, David C Fargo

Cell Genom· July 2024

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Interactive data sharing for multiple questionnaire-based exposome-wide association studies and exposome correlations in the Personalized Environment and Genes Study.
Dillon Lloyd, John S House, Farida S Akhtari, Charles P Schmitt, David C Fargo

Exposome· February 2024

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Questionnaire-based exposome-wide association studies for common diseases in the Personalized Environment and Genes Study.
Dillon Lloyd, John S House, Farida S Akhtari, Charles P Schmitt, David C Fargo

Exposome· February 2024

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Race/ethnicity-stratified fine-mapping of the MHC locus reveals genetic variants associated with late-onset asthma.
Eunice Y Lee, Wonson Choi, Adam B Burkholder, Lalith Perera, Jasmine A Mack, David C Fargo

Front Genet· June 2023

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Questionnaire-Based Polyexposure Assessment Outperforms Polygenic Scores for Classification of Type 2 Diabetes in a Multiancestry Cohort.
Farida S Akhtari, Dillon Lloyd, Adam Burkholder, Xiaoran Tong, John S House, David C Fargo

Diabetes Care· May 2023

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The skin is no barrier to mixtures: Air pollutant mixtures and reported psoriasis or eczema in the Personalized Environment and Genes Study (PEGS).
Melissa E Lowe, Farida S Akhtari, Taylor A Potter, David C Fargo, Charles P Schmitt

J Expo Sci Environ Epidemiol· May 2023

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Association of distance to swine concentrated animal feeding operations with immune-mediated diseases: An exploratory gene-environment study.
Montserrat Ayala-Ramirez, Nathaniel MacNell, Lucy E McNamee, John A McGrath, Farida S Akhtari, David C Fargo

Environ Int· January 2023

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Questionnaire-based exposome-wide association studies (ExWAS) reveal expected and novel risk factors associated with cardiovascular outcomes in the Personalized Environment and Genes Study.
Eunice Y Lee, Farida Akhtari, John S House, Ross J Simpson, Charles P Schmitt, David C Fargo

Environ Res· September 2022

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SIRT1 regulates cardiomyocyte alignment during maturation.
Yi Fang, Wei Fan, Xiaojiang Xu, Agnes K Janoshazi, David C Fargo

J Cell Sci· April 2022

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UV-exposure, endogenous DNA damage, and DNA replication errors shape the spectra of genome changes in human skin.
Natalie Saini, Camille K Giacobone, Leszek J Klimczak, Brian N Papas, Adam B Burkholder, David C Fargo

PLoS Genet· January 2021

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Ancestry-dependent gene expression correlates with reprogramming to pluripotency and multiple dynamic biological processes.
Laura S Bisogno, Jun Yang, Brian D Bennett, James M Ward, Lantz C Mackey, David C Fargo

Sci Adv· November 2020

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Correction: Repair of multiple simultaneous double-strand breaks causes bursts of genome-wide clustered hypermutation.
Cynthia J Sakofsky, Natalie Saini, Leszek J Klimczak, Kin Chan, Ewa P Malc, David Fargo

PLoS Biol· March 2020

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ORSO (Online Resource for Social Omics): A data-driven social network connecting scientists to genomics datasets.
Christopher A Lavender, Andrew J Shapiro, Frank S Day, David C Fargo

PLoS Comput Biol· January 2020

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Genome-wide mutagenesis resulting from topoisomerase 1-processing of unrepaired ribonucleotides in DNA.
Jessica S Williams, Scott A Lujan, Zhi-Xiong Zhou, Adam B Burkholder, Alan B Clark, David C Fargo

DNA Repair (Amst)· December 2019

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Repair of multiple simultaneous double-strand breaks causes bursts of genome-wide clustered hypermutation.
Cynthia J Sakofsky, Natalie Saini, Leszek J Klimczak, Kin Chan, Ewa P Malc, David Fargo

PLoS Biol· September 2019

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DNA methylation in mice is influenced by genetics as well as sex and life experience.
Sara A Grimm, Takashi Shimbo, Motoki Takaku, James W Thomas, Scott Auerbach, David C Fargo

Nat Commun· January 2019

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Revealing a human p53 universe.
Thuy-Ai T Nguyen, Sara A Grimm, Pierre R Bushel, Jianying Li, Yuanyuan Li, David C Fargo

Nucleic Acids Res· September 2018

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Muver, a computational framework for accurately calling accumulated mutations.
Adam B Burkholder, Scott A Lujan, Christopher A Lavender, Sara A Grimm, Thomas A Kunkel, David C Fargo

BMC Genomics· May 2018

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Widespread transcriptional pausing and elongation control at enhancers.
Telmo Henriques, Benjamin S Scruggs, Michiko O Inouye, Ginger W Muse, Lucy H Williams, David C Fargo

Genes Dev· January 2018

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Methionine metabolism is essential for SIRT1-regulated mouse embryonic stem cell maintenance and embryonic development.
Shuang Tang, Yi Fang, Gang Huang, Xiaojiang Xu, Elizabeth Padilla-Banks, David C Fargo

EMBO J· November 2017

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Intestinal Epithelial Sirtuin 1 Regulates Intestinal Inflammation During Aging in Mice by Altering the Intestinal Microbiota.
Alicia S Wellman, Mallikarjuna R Metukuri, Nevzat Kazgan, Xiaojiang Xu, Qing Xu, David C Fargo

Gastroenterology· September 2017

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ORIO (Online Resource for Integrative Omics): a web-based platform for rapid integration of next generation sequencing data.
Christopher A Lavender, Andrew J Shapiro, Adam B Burkholder, Brian D Bennett, Karen Adelman, David C Fargo

Nucleic Acids Res· June 2017

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