Publications by authors named "David Filman"

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Viral DNA polymerase structures reveal mechanisms of antiviral drug resistance.
Sundaresh Shankar, Junhua Pan, Pan Yang, Yuemin Bian, Gábor Oroszlán, David J Filman

Cell· October 2024

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Mechanism of enterovirus VP0 maturation cleavage based on the structure of a stabilised assembly intermediate.
Natalie J Kingston, Joseph S Snowden, Keith Grehan, Philippa K Hall, Eero V Hietanen, David J Filman

PLoS Pathog· September 2024

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Mechanism of enterovirus VP0 maturation cleavage based on the structure of a stabilised assembly intermediate.
Natalie J Kingston, Joseph S Snowden, Keith Grehan, Philippa K Hall, Eero V Hietanen, David J Filman

bioRxiv· April 2024

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Resistance to a Nucleoside Analog Antiviral Drug from More Rapid Extension of Drug-Containing Primers.
Han Chen, Jessica L Lawler, David J Filman, James M Hogle, Donald M Coen

mBio· February 2021

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Real-Time Imaging of Polioviral RNA Translocation across a Membrane.
Krishanthi S Karunatilaka, David J Filman, Mike Strauss, Joseph J Loparo, James M Hogle

mBio· February 2021

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Cryo-EM structures reveal two distinct conformational states in a picornavirus cell entry intermediate.
Pranav N M Shah, David J Filman, Krishanthi S Karunatilaka, Emma L Hesketh, Elisabetta Groppelli

PLoS Pathog· September 2020

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Cryo-EM reveals the structural basis of long-range electron transport in a cytochrome-based bacterial nanowire.
David J Filman, Stephen F Marino, Joy E Ward, Lu Yang, Zoltán Mester

Commun Biol· April 2020

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Getting to and through the inner nuclear membrane during herpesvirus nuclear egress.
Ming F Lye, Adrian R Wilkie, David J Filman, James M Hogle, Donald M Coen

Curr Opin Cell Biol· June 2017

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Cryo-electron Microscopy Structures of Expanded Poliovirus with VHHs Sample the Conformational Repertoire of the Expanded State.
Mike Strauss, Lise Schotte, Krishanthi S Karunatilaka, David J Filman, James M Hogle

J Virol· February 2017

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A Small Covalent Allosteric Inhibitor of Human Cytomegalovirus DNA Polymerase Subunit Interactions.
Han Chen, Molly Coseno, Scott B Ficarro, My Sam Mansueto, Gloria Komazin-Meredith, David J Filman

ACS Infect Dis· February 2017

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Five of Five VHHs Neutralizing Poliovirus Bind the Receptor-Binding Site.
Mike Strauss, Lise Schotte, Bert Thys, David J Filman, James M Hogle

J Virol· January 2016

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Unexpected features and mechanism of heterodimer formation of a herpesvirus nuclear egress complex.
Ming F Lye, Mayuri Sharma, Kamel El Omari, David J Filman, Jonathan P Schuermann

EMBO J· December 2015

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Characterization of Poliovirus Neutralization Escape Mutants of Single-Domain Antibody Fragments (VHHs).
Lise Schotte, Bert Thys, Mike Strauss, David J Filman, Bart Rombaut

Antimicrob Agents Chemother· August 2015

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Structure of a herpesvirus nuclear egress complex subunit reveals an interaction groove that is essential for viral replication.
Kendra E Leigh, Mayuri Sharma, My Sam Mansueto, Andras Boeszoermenyi, David J Filman

Proc Natl Acad Sci U S A· July 2015

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Nectin-like interactions between poliovirus and its receptor trigger conformational changes associated with cell entry.
Mike Strauss, David J Filman, David M Belnap, Naiqian Cheng, Roane T Noel

J Virol· April 2015

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Structural dynamics as a contributor to error-prone replication by an RNA-dependent RNA polymerase.
Ibrahim M Moustafa, Victoria K Korboukh, Jamie J Arnold, Eric D Smidansky, Laura L Marcotte, David Filman

J Biol Chem· December 2014

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Mechanism of action and capsid-stabilizing properties of VHHs with an in vitro antipolioviral activity.
Lise Schotte, Mike Strauss, Bert Thys, Hadewych Halewyck, David J Filman

J Virol· April 2014

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Cryo-electron microscopy reconstruction shows poliovirus 135S particles poised for membrane interaction and RNA release.
Carmen Butan, David J Filman, James M Hogle

J Virol· February 2014

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RNA transfer from poliovirus 135S particles across membranes is mediated by long umbilical connectors.
Mike Strauss, Hazel C Levy, Mihnea Bostina, David J Filman, James M Hogle

J Virol· April 2013

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Structure of the Fab-labeled "breathing" state of native poliovirus.
Jun Lin, Lily Y Lee, Merja Roivainen, David J Filman, James M Hogle

J Virol· May 2012

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An externalized polypeptide partitions between two distinct sites on genome-released poliovirus particles.
Jun Lin, Naiqian Cheng, Marie Chow, David J Filman, Alasdair C Steven

J Virol· October 2011

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Poliovirus RNA is released from the capsid near a twofold symmetry axis.
Mihnea Bostina, Hazel Levy, David J Filman, James M Hogle

J Virol· January 2011

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Catching a virus in the act of RNA release: a novel poliovirus uncoating intermediate characterized by cryo-electron microscopy.
Hazel C Levy, Mihnea Bostina, David J Filman, James M Hogle

J Virol· May 2010

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The crystal structure of PF-8, the DNA polymerase accessory subunit from Kaposi's sarcoma-associated herpesvirus.
Jennifer L Baltz, David J Filman, Mihai Ciustea, Janice Elaine Y Silverman, Catherine L Lautenschlager

J Virol· December 2009

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The human cytomegalovirus UL44 C clamp wraps around DNA.
Gloria Komazin-Meredith, Robert J Petrella, Webster L Santos, David J Filman, James M Hogle

Structure· August 2008

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