Publications by authors named "David Flyer"

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Author Correction: Intradermal immunization by Ebola virus GP subunit vaccines using microneedle patches protects mice against lethal EBOV challenge.
Ying Liu, Ling Ye, Fang Lin, Yasmine Gomaa, David Flyer

Sci Rep· August 2023

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Randomized, Blinded, Dose-Ranging Trial of an Ebola Virus Glycoprotein Nanoparticle Vaccine With Matrix-M Adjuvant in Healthy Adults.
Louis Fries, Iksung Cho, Verena Krähling, Sarah K Fehling, Thomas Strecker, David Flyer

J Infect Dis· July 2020

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Maternal immunization with RSV fusion glycoprotein vaccine and substantial protection of neonatal baboons against respiratory syncytial virus pulmonary challenge.
Robert C Welliver, James F Papin, Alisha Preno, Vadim Ivanov, Jing-Hui Tian, David Flyer

Vaccine· January 2020

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Structure basis of neutralization by a novel site II/IV antibody against respiratory syncytial virus fusion protein.
Qingqing Xie, Zhao Wang, Fengyun Ni, Xiaorui Chen, Jianpeng Ma, David Flyer

PLoS One· October 2019

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Intradermal Vaccination With Adjuvanted Ebola Virus Soluble Glycoprotein Subunit Vaccine by Microneedle Patches Protects Mice Against Lethal Ebola Virus Challenge.
Ying Liu, Ling Ye, Fang Lin, Yasmine Gomaa, David Flyer

J Infect Dis· November 2018

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Intradermal immunization by Ebola virus GP subunit vaccines using microneedle patches protects mice against lethal EBOV challenge.
Ying Liu, Ling Ye, Fang Lin, Yasmine Gomaa, David Flyer

Sci Rep· July 2018

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Improved Titers against Influenza Drift Variants with a Nanoparticle Vaccine.
Vivek Shinde, Louis Fries, Yukun Wu, Sapeckshita Agrawal, Iksung Cho, David Flyer

N Engl J Med· June 2018

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Neuraminidase-based recombinant virus-like particles protect against lethal avian influenza A(H5N1) virus infection in ferrets.
Gale E Smith, Xiangjie Sun, Yaohui Bai, Ye V Liu, Michael J Massare, David Flyer

Virology· September 2017

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Novel hemagglutinin nanoparticle influenza vaccine with Matrix-M™ adjuvant induces hemagglutination inhibition, neutralizing, and protective responses in ferrets against homologous and drifted A(H3N2) subtypes.
Gale Smith, Ye Liu, David Flyer, Michael J Massare, Bin Zhou

Vaccine· September 2017

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Clostridium difficile chimeric toxin receptor binding domain vaccine induced protection against different strains in active and passive challenge models.
Jing-Hui Tian, Gregory Glenn, David Flyer, Bin Zhou, Ye Liu

Vaccine· July 2017

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MERS-CoV spike nanoparticles protect mice from MERS-CoV infection.
Christopher M Coleman, Thiagarajan Venkataraman, Ye V Liu, Gregory M Glenn, Gale E Smith, David C Flyer

Vaccine· March 2017

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Matrix-M adjuvant enhances antibody, cellular and protective immune responses of a Zaire Ebola/Makona virus glycoprotein (GP) nanoparticle vaccine in mice.
Karin Lövgren Bengtsson, Haifeng Song, Linda Stertman, Ye Liu, David C Flyer

Vaccine· April 2016

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A Randomized, Blinded, Controlled, Dose-Ranging Study of a Respiratory Syncytial Virus Recombinant Fusion (F) Nanoparticle Vaccine in Healthy Women of Childbearing Age.
Gregory M Glenn, Louis F Fries, D Nigel Thomas, Gale Smith, Eloi Kpamegan, David Flyer

J Infect Dis· February 2016

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Human polyclonal immunoglobulin G from transchromosomic bovines inhibits MERS-CoV in vivo.
Thomas Luke, Hua Wu, Jincun Zhao, Rudragouda Channappanavar, Christopher M Coleman, David Flyer

Sci Transl Med· February 2016

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Modeling maternal fetal RSV F vaccine induced antibody transfer in guinea pigs.
Gregory M Glenn, Louis F Fries, Gale Smith, Eloi Kpamegan, Hanxin Lu, David Flyer

Vaccine· November 2015

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An insect cell derived respiratory syncytial virus (RSV) F nanoparticle vaccine induces antigenic site II antibodies and protects against RSV challenge in cotton rats by active and passive immunization.
Rama Raghunandan, Hanxin Lu, Bin Zhou, Mimi Guebre Xabier, Michael J Massare, David C Flyer

Vaccine· November 2014

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Purified coronavirus spike protein nanoparticles induce coronavirus neutralizing antibodies in mice.
Christopher M Coleman, Ye V Liu, Haiyan Mu, Justin K Taylor, Michael Massare, David C Flyer

Vaccine· May 2014

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Immunostimulant patches containing Escherichia coli LT enhance immune responses to DNA- and recombinant protein-based Alzheimer's disease vaccines.
Hayk Davtyan, Anahit Ghochikyan, Armine Hovakimyan, Irina Petrushina, Jianmei Yu, David Flyer

J Neuroimmunol· March 2014

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Development of influenza H7N9 virus like particle (VLP) vaccine: homologous A/Anhui/1/2013 (H7N9) protection and heterologous A/chicken/Jalisco/CPA1/2012 (H7N3) cross-protection in vaccinated mice challenged with H7N9 virus.
Gale E Smith, David C Flyer, Ramadevi Raghunandan, Ye Liu, Ziping Wei

Vaccine· September 2013

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Respiratory syncytial virus fusion glycoprotein expressed in insect cells form protein nanoparticles that induce protective immunity in cotton rats.
Gale Smith, Rama Raghunandan, Yingyun Wu, Ye Liu, Michael Massare, David Flyer

PLoS One· May 2013

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A novel fusion protein containing the receptor binding domains of C. difficile toxin A and toxin B elicits protective immunity against lethal toxin and spore challenge in preclinical efficacy models.
Jing-Hui Tian, Steven R Fuhrmann, Stefanie Kluepfel-Stahl, Robert J Carman, Larry Ellingsworth, David C Flyer

Vaccine· June 2012

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Transcutaneous immunization with Intercell's vaccine delivery system.
Robert C Seid, Jee Loon Look, Christian Ruiz, Vladimir Frolov, David Flyer

Vaccine· June 2012

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Safety and immunogenicity of an influenza vaccine A/H5N1 (A/Vietnam/1194/2004) when coadministered with a heat-labile enterotoxin (LT) adjuvant patch.
Gregory M Glenn, D Nigel Thomas, Kimber L Poffenberger, David C Flyer, Larry R Ellingsworth

Vaccine· December 2009

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Use of a patch containing heat-labile toxin from Escherichia coli against travellers' diarrhoea: a phase II, randomised, double-blind, placebo-controlled field trial.
Sarah A Frech, Herbert L Dupont, A Louis Bourgeois, Robin McKenzie, Jaime Belkind-Gerson, David C Flyer

Lancet· June 2008

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Controlled, single-step, stratum corneum disruption as a pretreatment for immunization via a patch.
David M Frerichs, Larry R Ellingsworth, Sarah A Frech, David C Flyer, Christina P Villar

Vaccine· May 2008

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