Publications by authors named "David Fram"

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Epidemiology and Outcomes of Antibiotic De-escalation in Patients With Suspected Sepsis in US Hospitals.
Kai Qian Kam, Tom Chen, Sameer S Kadri, Alexander Lawandi, Christina Yek, David Fram

Clin Infect Dis· February 2025

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Trends in Empiric Broad-Spectrum Antibiotic Use for Suspected Community-Onset Sepsis in US Hospitals.
Chanu Rhee, Tom Chen, Sameer S Kadri, Alexander Lawandi, Christina Yek, David Fram

JAMA Netw Open· June 2024

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Association Between Implementation of the Severe Sepsis and Septic Shock Early Management Bundle Performance Measure and Outcomes in Patients With Suspected Sepsis in US Hospitals.
Chanu Rhee, Tingting Yu, Rui Wang, Sameer S Kadri, David Fram

JAMA Netw Open· December 2021

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Impact of Risk Adjustment Using Clinical vs Administrative Data on Hospital Sepsis Mortality Comparisons.
Chanu Rhee, Zhonghe Li, Rui Wang, Yue Song, Sameer S Kadri, David Fram

Open Forum Infect Dis· June 2020

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Prevalence of Antibiotic-Resistant Pathogens in Culture-Proven Sepsis and Outcomes Associated With Inadequate and Broad-Spectrum Empiric Antibiotic Use.
Chanu Rhee, Sameer S Kadri, John P Dekker, Robert L Danner, Huai-Chun Chen, David Fram

JAMA Netw Open· April 2020

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A Novel Approach to Visualize Risk Minimization Effectiveness: Peeping at the 2012 UK Proton Pump Inhibitor Label Change Using a Rapid Cycle Analysis Tool.
Rachel E Sobel, William Blackwell, David M Fram, Andrew Bate

Drug Saf· November 2019

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Risk Adjustment for Sepsis Mortality to Facilitate Hospital Comparisons Using Centers for Disease Control and Prevention's Adult Sepsis Event Criteria and Routine Electronic Clinical Data.
Chanu Rhee, Rui Wang, Yue Song, Zilu Zhang, Sameer S Kadri, David Fram

Crit Care Explor· October 2019

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Epidemiology of Hospital-Onset Versus Community-Onset Sepsis in U.S. Hospitals and Association With Mortality: A Retrospective Analysis Using Electronic Clinical Data.
Chanu Rhee, Rui Wang, Zilu Zhang, David Fram, Sameer S Kadri

Crit Care Med· September 2019

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Does Obesity Protect Against Death in Sepsis? A Retrospective Cohort Study of 55,038 Adult Patients.
Dominique J Pepper, Cumhur Y Demirkale, Junfeng Sun, Chanu Rhee, David Fram

Crit Care Med· May 2019

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Variation in Identifying Sepsis and Organ Dysfunction Using Administrative Versus Electronic Clinical Data and Impact on Hospital Outcome Comparisons.
Chanu Rhee, Maximilian S Jentzsch, Sameer S Kadri, Christopher W Seymour, Derek C Angus, David Fram

Crit Care Med· April 2019

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Sepsis Surveillance Using Adult Sepsis Events Simplified eSOFA Criteria Versus Sepsis-3 Sequential Organ Failure Assessment Criteria.
Chanu Rhee, Zilu Zhang, Sameer S Kadri, David J Murphy, Greg S Martin, David Fram

Crit Care Med· March 2019

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Development of a mother-child database for drug exposure and adverse event detection in the Military Health System.
Lockwood G Taylor, Rosenie Thelus Jean, Geoff Gordon, David Fram, Trinka Coster

Pharmacoepidemiol Drug Saf· May 2015

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Automated method for detecting increases in frequency of spontaneous adverse event reports over time.
William DuMouchel, Nancy Yuen, Nassrin Payvandi, Wendy Booth, Andrew Rut, David Fram

J Biopharm Stat· October 2013

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Molecular clinical safety intelligence: a system for bridging clinically focused safety knowledge to early-stage drug discovery - the GSK experience.
Dana E Vanderwall, Nancy Yuen, Mohammad Al-Ansari, James Bailey, David Fram

Drug Discov Today· August 2011

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Adaptation of Bayesian data mining algorithms to longitudinal claims data: coxib safety as an example.
Jeffrey R Curtis, Hong Cheng, Elizabeth Delzell, David Fram, Meredith Kilgore

Med Care· September 2008

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Antipsychotics, glycemic disorders, and life-threatening diabetic events: a Bayesian data-mining analysis of the FDA adverse event reporting system (1968-2004).
William DuMouchel, David Fram, Xionghu Yang, Ramy A Mahmoud, Amy L Grogg

Ann Clin Psychiatry· April 2008

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Psychogenic camptocormia.
Frank Skidmore, Karen Anderson, David Fram, William Weiner

Mov Disord· October 2007

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Signal detection methodologies to support effective safety management.
Robbert P van Manen, David Fram, William DuMouchel

Expert Opin Drug Saf· July 2007

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Comparative performance of two quantitative safety signalling methods: implications for use in a pharmacovigilance department.
June S Almenoff, Karol K LaCroix, Nancy A Yuen, David Fram, William DuMouchel

Drug Saf· January 2007

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Using simulation to assess the sensitivity and specificity of a signal detection tool for multidimensional public health surveillance data.
Henry Rolka, Dwayne Bracy, Channing Russell, David Fram, Robert Ball

Stat Med· February 2005

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Association of asthma therapy and Churg-Strauss syndrome: an analysis of postmarketing surveillance data.
William DuMouchel, Eric T Smith, Richard Beasley, Harold Nelson, Xionghu Yang, David Fram

Clin Ther· July 2004

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Disproportionality analysis using empirical Bayes data mining: a tool for the evaluation of drug interactions in the post-marketing setting.
June S Almenoff, William DuMouchel, L Allen Kindman, Xionghu Yang, David Fram

Pharmacoepidemiol Drug Saf· September 2003

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Comparative study of electronic vs. paper VAS ratings: a randomized, crossover trial using healthy volunteers.
Robert N Jamison, Richard H Gracely, Stephen A Raymond, Jonathan G Levine, Barbara Marino, David Fram

Pain· September 2002

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