Publications by authors named "David Gate"

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Undulating changes in human plasma proteome profiles across the lifespan.
Benoit Lehallier, David Gate, Nicholas Schaum, Tibor Nanasi, Song Eun Lee, Hanadie Yousef, Patricia Moran Losada, Daniela Berdnik, Andreas Keller, Joe Verghese

December 2019

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The Sixth Annual Symposium of the Midwest Aging Consortium.
Ines Sturmlechner, Sarah A Ashiqueali, Hélène Martini, Karla Valdivieso, Ana Catarina Franco, David M Gate

J Gerontol A Biol Sci Med Sci· December 2025

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Mid-Infrared Photothermal Mesoscopy with Millimeter Field of View and Sub-micron Spatial Resolution.
Rong Tang, Jiaze Yin, Bethany Weinberg, Haonan Lin, Jiahui Lu, David Gate

bioRxiv· November 2025

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Unraveling neurovascular disease risk with MultiVINE-seq.
Lynn van Olst, David Gate

Neuron· October 2025

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The gut microbiome controls reactive astrocytosis during Aβ amyloidosis via propionate-mediated regulation of IL-17.
Sidhanth Chandra, Jelena Popovic, Naveen K Singhal, Elyse A Watkins, Hemraj B Dodiya, David Gate

J Clin Invest· July 2025

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Microglial mechanisms drive amyloid-β clearance in immunized patients with Alzheimer's disease.
Lynn van Olst, Brooke Simonton, Alex J Edwards, Anne V Forsyth, Jake Boles, David Gate

Nat Med· May 2025

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Author Correction: Microglial mechanisms drive amyloid-β clearance in immunized patients with Alzheimer's disease.
Lynn van Olst, Brooke Simonton, Alex J Edwards, Anne V Forsyth, Jake Boles, David Gate

Nat Med· May 2025

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Monocytes can efficiently replace all brain macrophages and fetal liver monocytes can generate bona fide SALL1 microglia.
Jonathan Bastos, Carleigh O'Brien, Mónica Vara-Pérez, Myrthe Mampay, Lynn van Olst, David Gate

Immunity· May 2025

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Clonally expanded, targetable, natural killer-like NKG7 T cells seed the aged spinal cord to disrupt myeloid-dependent wound healing.
Guiping Kong, Yayue Song, Yuyang Yan, Samantha M Calderazzo, Madhu Sudhana Saddala, David Gate

Neuron· March 2025

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A single-cell atlas to map sex-specific gene-expression changes in blood upon neurodegeneration.
Friederike Grandke, Tobias Fehlmann, Fabian Kern, David M Gate, Tobias William Wolff

Nat Commun· February 2025

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Applying single-cell and single-nucleus genomics to studies of cellular heterogeneity and cell fate transitions in the nervous system.
Igor Adameyko, Trygve Bakken, Aparna Bhaduri, Chintan Chhatbar, Mariella G Filbin, David Gate

Nat Neurosci· December 2024

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Neuronal ACE1 knockout disrupts the hippocampal renin angiotensin system leading to memory impairment and vascular loss in normal aging.
Sohee Jeon, Miranda A Salvo, Alia O Alia, Jelena Popovic, Mitchell Zagardo, David Gate

Neurobiol Dis· November 2024

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Anti-CD49d Ab treatment ameliorates age-associated inflammatory response and mitigates CD8 T-cell cytotoxicity after traumatic brain injury.
Zhangying Chen, Kacie P Ford, Mecca B A R Islam, Hanxiao Wan, Hyebin Han, David Gate

J Neuroinflammation· October 2024

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Deciphering spatial domains from spatial multi-omics with SpatialGlue.
Yahui Long, Kok Siong Ang, Raman Sethi, Sha Liao, Yang Heng, David Gate

Nat Methods· September 2024

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Advancements in APOE and dementia research: Highlights from the 2023 AAIC Advancements: APOE conference.
Courtney M Kloske, Michael E Belloy, Elizabeth E Blue, Gregory R Bowman, Maria C Carrillo, David Gate

Alzheimers Dement· September 2024

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antiCD49d Ab treatment ameliorates age-associated inflammatory response and mitigates CD8+ T-cell cytotoxicity after traumatic brain injury.
Zhangying Chen, Kacie P Ford, Mecca B A R Islam, Hanxiao Wan, Hyebin Han, David Gate

bioRxiv· June 2024

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Epigenetic dysregulation in Alzheimer's disease peripheral immunity.
Abhirami Ramakrishnan, Natalie Piehl, Brooke Simonton, Milan Parikh, Ziyang Zhang, David Gate

Neuron· April 2024

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Cerebrospinal fluid immune dysregulation during healthy brain aging and cognitive impairment.
Natalie Piehl, Lynn van Olst, Abhirami Ramakrishnan, Victoria Teregulova, Brooke Simonton, David Gate

Cell· December 2022

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New Perspectives on Immune Involvement in Parkinson's Disease Pathogenesis.
David Gate

J Parkinsons Dis· October 2022

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Transcriptomic Profiling Identifies CD8 T Cells in the Brain of Aged and Alzheimer's Disease Transgenic Mice as Tissue-Resident Memory T Cells.
Barbara Altendorfer, Michael Stefan Unger, Rodolphe Poupardin, Anna Hoog, Daniela Asslaber, David Gate

J Immunol· October 2022

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Infection and inflammation: New perspectives on Alzheimer's disease.
Heather E Whitson, Carol Colton, Joseph El Khoury, David Gate, Alison Goate

Brain Behav Immun Health· July 2022

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A human brain vascular atlas reveals diverse mediators of Alzheimer's risk.
Andrew C Yang, Ryan T Vest, Fabian Kern, Davis P Lee, Maayan Agam, David Gate

Nature· March 2022

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The CD22-IGF2R interaction is a therapeutic target for microglial lysosome dysfunction in Niemann-Pick type C.
John V Pluvinage, Jerry Sun, Christel Claes, Ryan A Flynn, Michael S Haney, David Gate

Sci Transl Med· December 2021

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CD4 T cells contribute to neurodegeneration in Lewy body dementia.
David Gate, Emma Tapp, Olivia Leventhal, Marian Shahid, Tim J Nonninger

Science· November 2021

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Publisher Correction: Dysregulation of brain and choroid plexus cell types in severe COVID-19.
Andrew C Yang, Fabian Kern, Patricia M Losada, Maayan R Agam, Christina A Maat, David Gate

Nature· October 2021

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Dysregulation of brain and choroid plexus cell types in severe COVID-19.
Andrew C Yang, Fabian Kern, Patricia M Losada, Maayan R Agam, Christina A Maat, David Gate

Nature· July 2021

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