参考。2019年のスタンフォード大学の研究。 Undulating changes in human plasma proteome profiles across the lifespan https://t.co/1X21c1JMtA
Undulating changes in human plasma proteome profiles across the lifespan.
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Dec 2019 – Jun 2025Where it's discussed
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What people are saying
Numerous discussions mention key insights from the research, such as the identification of critical transition points in aging at ages 34, 60, and 78. Phrases like 'distinct time periods of change' and 'non-linear changes' are indicative of a thoughtful engagement with the article's findings, suggesting that the choice of words conveys a sense of urgency and importance surrounding the relevance of these protein alterations to age-related diseases.
The majority of the discussions show a positive reaction towards the findings of the research.
Many posts reflect a high degree of curiosity and relevance, indicating that users find the topic significant.
While some posts mention the article's title repeatedly, several participants engage more by discussing specific aspects of the findings.
Users perceive the research as having a considerable impact on understanding aging and associated diseases.
Abstract in brief
- The study examines how the human plasma proteome, which includes proteins found in blood, changes significantly as people age, potentially revealing new insights into age-related diseases.
- Researchers analyzed blood samples from a diverse range of young adults to seniors (aged 18 to 89) and found distinct patterns of protein alterations at different life stages, particularly in the fourth, seventh, and eighth decades.
- This unique bioinformatics method not only highlights specific biological pathways associated with aging but also suggests new potential therapeutic targets for chronic diseases connected to aging.
Top posts
Most liked on X and Bluesky~1y ago, @blehall et al published https://t.co/wsfMk9icDT. 4263 M+F age 18-95, INTERVAL & LonGenity cohorts, 2925 proteins measured by SOMAmers. A wealth of data but, but paper focused on 1) the cool observation that many age-related changes are non-linear... https://t.co/C8edjLS9rI
Undulating changes in human plasma proteome profiles across the lifespan | Nature Medicine https://t.co/G6Rwcyaqdn
@LizRose14449371 @davidasinclair @cashdaddies444 @isbsci @sema4 @IcahnMountSinai @manoliskellis @lsmarr @SnyderShot @JeffBezos @elonmusk @wysscoray From ~10:00 in the video. Paper: Undulating changes in human plasma proteome profiles across the lifespan. 2019 https://t.co/UFBuJCTFR9
Lehallier, B., Gate, D., Schaum, N. et al. Undulating changes in human plasma proteome profiles across the lifespan. Nat Med 25, 1843–1850 (2019) doi:10.1038/s41591-019-0673-2 @jpsenescence @AndreaBMaier @BertrandFougere @drjohnmorley @GeriSoc @britgerontology @livuniITM @MPUoL https://t.co/RgoV6fxIwE
All mentions
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Significant Age-Related Changes in Human Health at 44 and 60
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@schw90 If you look at blood proteins for example, there are three transition points. https://t.co/oMe8zqjfHb https://t.co/YjQpIoSPHs
RT @gglinskii: Undulating changes in human plasma proteome profiles across the lifespan. https://t.co/2x9CL9tHOB
RT @gglinskii: Undulating changes in human plasma proteome profiles across the lifespan. https://t.co/2x9CL9tHOB
RT @DrNithi: Undulating changes in human plasma proteome profiles across the lifespan | Nature Medicine เป็นอันขบวนการแก่จริงจังเห็นได้ชัด…
Undulating changes in human plasma proteome profiles across the lifespan | Nature Medicine เป็นอันขบวนการแก่จริงจังเห็นได้ชัด ช่วงอายุ 40 70 และ 80 นะครับ ผ่านพ้นไปได้อาจได้อยู่ยาว
Undulating changes in human plasma proteome profiles across the lifespan. https://t.co/2x9CL9tHOB
Undulating changes in human plasma proteome profiles across the lifespan https://t.co/iT55nQhtVu
Undulating changes in human plasma proteome profiles across the lifespan | Nature Medicine https://t.co/eI4ZMkDK5g
Undulating changes in human plasma proteome profiles across the lifespan https://t.co/iT55nQhtVu
RT @GlobalPHObserv: Undulating changes in human plasma proteome profiles across the lifespan | Nature Medicine https://t.co/G6Rwcyaqdn
RT @GlobalPHObserv: Undulating changes in human plasma proteome profiles across the lifespan | Nature Medicine https://t.co/G6Rwcyaqdn
Undulating changes in human plasma proteome profiles across the lifespan | Nature Medicine https://t.co/G6Rwcyaqdn
@yeeseak no cost Undulating changes in human plasma proteome profiles across the lifespan (I thought the newer version was in English but it was in French) https://t.co/LLzCmpoCgl
Undulating changes in human plasma proteome profiles across the lifespan | Nature Medicine https://t.co/oZFXbOKhYL
Undulating changes in human plasma proteome profiles across the lifespan | Nature Medicine // 人間は34歳で一気に老化が進むという論文。あとで読む。 https://t.co/VuBXdxsIUK
@pamki eso pensé... y seguro es una de las razones principales de esa falta de energía. Y pues tambien es la edad del primer tipping point de envejecimiento. Parece que no envejecemos de forma continua sino asaltos a los (en promedio): 34, 60 y 78 año https://t.co/THg4CDe6ZZ
RT @h_okumura: ヒトの老化は、34歳、60歳、78歳で急激に進むことがわかった https://t.co/yAJIakUG6Z Undulating changes in human plasma proteome profiles across the life…
Clonal dynamics of haematopoiesis across the human lifespan. https://t.co/vqFVxCusVw Undulating changes in human plasma proteome profiles across the lifespan. https://t.co/S0F9HRELvl
RT @h_okumura: ヒトの老化は、34歳、60歳、78歳で急激に進むことがわかった https://t.co/yAJIakUG6Z Undulating changes in human plasma proteome profiles across the life…
RT @ekuro0513: 参考。2019年のスタンフォード大学の研究。 Undulating changes in human plasma proteome profiles across the lifespan https://t.co/1X21c1JMtA
参考。2019年のスタンフォード大学の研究。 Undulating changes in human plasma proteome profiles across the lifespan https://t.co/1X21c1JMtA
@LizRose14449371 @davidasinclair @cashdaddies444 @isbsci @sema4 @IcahnMountSinai @manoliskellis @lsmarr @SnyderShot @JeffBezos @elonmusk @wysscoray From ~10:00 in the video. Paper: Undulating changes in human plasma proteome profiles across the lifespan. 2019 https://t.co/UFBuJCTFR9
RT @Pluchinolab: Undulating changes in human plasma proteome profiles across the lifespan | Nature Medicine https://t.co/oNWIjfEda3
Undulating changes in human plasma proteome profiles across the lifespan https://t.co/BRyncHEjRC via @instapaper
Undulating changes in human plasma proteome profiles across the lifespan https://t.co/AyB1zM8gm2
~1y ago, @blehall et al published https://t.co/wsfMk9icDT. 4263 M+F age 18-95, INTERVAL & LonGenity cohorts, 2925 proteins measured by SOMAmers. A wealth of data but, but paper focused on 1) the cool observation that many age-related changes are non-linear... https://t.co/C8edjLS9rI
RT @TheAgingField: His presented work were recently published here: Plasma proteome changes with age: https://t.co/kKpgRyO6dK Plasma pro…
His presented work were recently published here: Plasma proteome changes with age: https://t.co/kKpgRyO6dK Plasma protein transport to the brain: https://t.co/CHtkDi6SFl
米スタンフォード大学のトニー・ウィス=コレイ教授 Undulating changes in human plasma proteome profiles across the lifespan | Nature Medicine https://t.co/dnVIvq0yRZ
RT @h_okumura: ヒトの老化は、34歳、60歳、78歳で急激に進むことがわかった https://t.co/yAJIakUG6Z Undulating changes in human plasma proteome profiles across the life…
RT @h_okumura: ヒトの老化は、34歳、60歳、78歳で急激に進むことがわかった https://t.co/yAJIakUG6Z Undulating changes in human plasma proteome profiles across the life…
RT @h_okumura: ヒトの老化は、34歳、60歳、78歳で急激に進むことがわかった https://t.co/yAJIakUG6Z Undulating changes in human plasma proteome profiles across the life…
RT @h_okumura: ヒトの老化は、34歳、60歳、78歳で急激に進むことがわかった https://t.co/yAJIakUG6Z Undulating changes in human plasma proteome profiles across the life…
RT @PastelBio: Undulating changes in human plasma proteome profiles across the lifespan | https://t.co/DQrTOsIktz #proteomics https://t.co/…
Undulating changes in human plasma proteome profiles across the lifespan | https://t.co/DQrTOsIktz #proteomics https://t.co/F0AZAs87oS
Undulating changes in human plasma proteome profiles across the lifespan. - PubMed - NCBI https://t.co/PRfM3xQeXP Identifying physiological age is becoming a reality
RT @h_okumura: ヒトの老化は、34歳、60歳、78歳で急激に進むことがわかった https://t.co/yAJIakUG6Z Undulating changes in human plasma proteome profiles across the life…
RT @h_okumura: ヒトの老化は、34歳、60歳、78歳で急激に進むことがわかった https://t.co/yAJIakUG6Z Undulating changes in human plasma proteome profiles across the life…
RT @h_okumura: ヒトの老化は、34歳、60歳、78歳で急激に進むことがわかった https://t.co/yAJIakUG6Z Undulating changes in human plasma proteome profiles across the life…
RT @h_okumura: ヒトの老化は、34歳、60歳、78歳で急激に進むことがわかった https://t.co/yAJIakUG6Z Undulating changes in human plasma proteome profiles across the life…
RT @h_okumura: ヒトの老化は、34歳、60歳、78歳で急激に進むことがわかった https://t.co/yAJIakUG6Z Undulating changes in human plasma proteome profiles across the life…
RT @h_okumura: ヒトの老化は、34歳、60歳、78歳で急激に進むことがわかった https://t.co/yAJIakUG6Z Undulating changes in human plasma proteome profiles across the life…
RT @h_okumura: ヒトの老化は、34歳、60歳、78歳で急激に進むことがわかった https://t.co/yAJIakUG6Z Undulating changes in human plasma proteome profiles across the life…
RT @h_okumura: ヒトの老化は、34歳、60歳、78歳で急激に進むことがわかった https://t.co/yAJIakUG6Z Undulating changes in human plasma proteome profiles across the life…
RT @h_okumura: ヒトの老化は、34歳、60歳、78歳で急激に進むことがわかった https://t.co/yAJIakUG6Z Undulating changes in human plasma proteome profiles across the life…
RT @h_okumura: ヒトの老化は、34歳、60歳、78歳で急激に進むことがわかった https://t.co/yAJIakUG6Z Undulating changes in human plasma proteome profiles across the life…
RT @h_okumura: ヒトの老化は、34歳、60歳、78歳で急激に進むことがわかった https://t.co/yAJIakUG6Z Undulating changes in human plasma proteome profiles across the life…
RT @h_okumura: ヒトの老化は、34歳、60歳、78歳で急激に進むことがわかった https://t.co/yAJIakUG6Z Undulating changes in human plasma proteome profiles across the life…
RT @h_okumura: ヒトの老化は、34歳、60歳、78歳で急激に進むことがわかった https://t.co/yAJIakUG6Z Undulating changes in human plasma proteome profiles across the life…
RT @h_okumura: ヒトの老化は、34歳、60歳、78歳で急激に進むことがわかった https://t.co/yAJIakUG6Z Undulating changes in human plasma proteome profiles across the life…
RT @h_okumura: ヒトの老化は、34歳、60歳、78歳で急激に進むことがわかった https://t.co/yAJIakUG6Z Undulating changes in human plasma proteome profiles across the life…
RT @h_okumura: ヒトの老化は、34歳、60歳、78歳で急激に進むことがわかった https://t.co/yAJIakUG6Z Undulating changes in human plasma proteome profiles across the life…
RT @h_okumura: ヒトの老化は、34歳、60歳、78歳で急激に進むことがわかった https://t.co/yAJIakUG6Z Undulating changes in human plasma proteome profiles across the life…
RT @h_okumura: ヒトの老化は、34歳、60歳、78歳で急激に進むことがわかった https://t.co/yAJIakUG6Z Undulating changes in human plasma proteome profiles across the life…
RT @h_okumura: ヒトの老化は、34歳、60歳、78歳で急激に進むことがわかった https://t.co/yAJIakUG6Z Undulating changes in human plasma proteome profiles across the life…
Undulating changes in human plasma proteome profiles across the lifespan https://t.co/cPitc76yZA
Undulating changes in human plasma proteome profiles across the lifespan https://t.co/vMjPZ6ejZd
RT @h_okumura: ヒトの老化は、34歳、60歳、78歳で急激に進むことがわかった https://t.co/yAJIakUG6Z Undulating changes in human plasma proteome profiles across the life…
RT @h_okumura: ヒトの老化は、34歳、60歳、78歳で急激に進むことがわかった https://t.co/yAJIakUG6Z Undulating changes in human plasma proteome profiles across the life…
RT @h_okumura: ヒトの老化は、34歳、60歳、78歳で急激に進むことがわかった https://t.co/yAJIakUG6Z Undulating changes in human plasma proteome profiles across the life…
RT @h_okumura: ヒトの老化は、34歳、60歳、78歳で急激に進むことがわかった https://t.co/yAJIakUG6Z Undulating changes in human plasma proteome profiles across the life…
RT @h_okumura: ヒトの老化は、34歳、60歳、78歳で急激に進むことがわかった https://t.co/yAJIakUG6Z Undulating changes in human plasma proteome profiles across the life…
RT @h_okumura: ヒトの老化は、34歳、60歳、78歳で急激に進むことがわかった https://t.co/yAJIakUG6Z Undulating changes in human plasma proteome profiles across the life…
RT @h_okumura: ヒトの老化は、34歳、60歳、78歳で急激に進むことがわかった https://t.co/yAJIakUG6Z Undulating changes in human plasma proteome profiles across the life…
RT @h_okumura: ヒトの老化は、34歳、60歳、78歳で急激に進むことがわかった https://t.co/yAJIakUG6Z Undulating changes in human plasma proteome profiles across the life…
Undulating changes in human plasma proteome profiles across the lifespan -> https://t.co/exfbl7CiRn https://t.co/74U22N18Y4
RT @h_okumura: ヒトの老化は、34歳、60歳、78歳で急激に進むことがわかった https://t.co/yAJIakUG6Z Undulating changes in human plasma proteome profiles across the life…
RT @h_okumura: ヒトの老化は、34歳、60歳、78歳で急激に進むことがわかった https://t.co/yAJIakUG6Z Undulating changes in human plasma proteome profiles across the life…
RT @h_okumura: ヒトの老化は、34歳、60歳、78歳で急激に進むことがわかった https://t.co/yAJIakUG6Z Undulating changes in human plasma proteome profiles across the life…
RT @h_okumura: ヒトの老化は、34歳、60歳、78歳で急激に進むことがわかった https://t.co/yAJIakUG6Z Undulating changes in human plasma proteome profiles across the life…
RT @h_okumura: ヒトの老化は、34歳、60歳、78歳で急激に進むことがわかった https://t.co/yAJIakUG6Z Undulating changes in human plasma proteome profiles across the life…
RT @h_okumura: ヒトの老化は、34歳、60歳、78歳で急激に進むことがわかった https://t.co/yAJIakUG6Z Undulating changes in human plasma proteome profiles across the life…
RT @h_okumura: ヒトの老化は、34歳、60歳、78歳で急激に進むことがわかった https://t.co/yAJIakUG6Z Undulating changes in human plasma proteome profiles across the life…
RT @h_okumura: ヒトの老化は、34歳、60歳、78歳で急激に進むことがわかった https://t.co/yAJIakUG6Z Undulating changes in human plasma proteome profiles across the life…
RT @h_okumura: ヒトの老化は、34歳、60歳、78歳で急激に進むことがわかった https://t.co/yAJIakUG6Z Undulating changes in human plasma proteome profiles across the life…
RT @h_okumura: ヒトの老化は、34歳、60歳、78歳で急激に進むことがわかった https://t.co/yAJIakUG6Z Undulating changes in human plasma proteome profiles across the life…
RT @h_okumura: ヒトの老化は、34歳、60歳、78歳で急激に進むことがわかった https://t.co/yAJIakUG6Z Undulating changes in human plasma proteome profiles across the life…
RT @h_okumura: ヒトの老化は、34歳、60歳、78歳で急激に進むことがわかった https://t.co/yAJIakUG6Z Undulating changes in human plasma proteome profiles across the life…
RT @h_okumura: ヒトの老化は、34歳、60歳、78歳で急激に進むことがわかった https://t.co/yAJIakUG6Z Undulating changes in human plasma proteome profiles across the life…
RT @h_okumura: ヒトの老化は、34歳、60歳、78歳で急激に進むことがわかった https://t.co/yAJIakUG6Z Undulating changes in human plasma proteome profiles across the life…
RT @h_okumura: ヒトの老化は、34歳、60歳、78歳で急激に進むことがわかった https://t.co/yAJIakUG6Z Undulating changes in human plasma proteome profiles across the life…
RT @h_okumura: ヒトの老化は、34歳、60歳、78歳で急激に進むことがわかった https://t.co/yAJIakUG6Z Undulating changes in human plasma proteome profiles across the life…
RT @h_okumura: ヒトの老化は、34歳、60歳、78歳で急激に進むことがわかった https://t.co/yAJIakUG6Z Undulating changes in human plasma proteome profiles across the life…
RT @h_okumura: ヒトの老化は、34歳、60歳、78歳で急激に進むことがわかった https://t.co/yAJIakUG6Z Undulating changes in human plasma proteome profiles across the life…
RT @h_okumura: ヒトの老化は、34歳、60歳、78歳で急激に進むことがわかった https://t.co/yAJIakUG6Z Undulating changes in human plasma proteome profiles across the life…
RT @h_okumura: ヒトの老化は、34歳、60歳、78歳で急激に進むことがわかった https://t.co/yAJIakUG6Z Undulating changes in human plasma proteome profiles across the life…
RT @h_okumura: ヒトの老化は、34歳、60歳、78歳で急激に進むことがわかった https://t.co/yAJIakUG6Z Undulating changes in human plasma proteome profiles across the life…
RT @h_okumura: ヒトの老化は、34歳、60歳、78歳で急激に進むことがわかった https://t.co/yAJIakUG6Z Undulating changes in human plasma proteome profiles across the life…
RT @h_okumura: ヒトの老化は、34歳、60歳、78歳で急激に進むことがわかった https://t.co/yAJIakUG6Z Undulating changes in human plasma proteome profiles across the life…
RT @h_okumura: ヒトの老化は、34歳、60歳、78歳で急激に進むことがわかった https://t.co/yAJIakUG6Z Undulating changes in human plasma proteome profiles across the life…
RT @h_okumura: ヒトの老化は、34歳、60歳、78歳で急激に進むことがわかった https://t.co/yAJIakUG6Z Undulating changes in human plasma proteome profiles across the life…
RT @h_okumura: ヒトの老化は、34歳、60歳、78歳で急激に進むことがわかった https://t.co/yAJIakUG6Z Undulating changes in human plasma proteome profiles across the life…
RT @h_okumura: ヒトの老化は、34歳、60歳、78歳で急激に進むことがわかった https://t.co/yAJIakUG6Z Undulating changes in human plasma proteome profiles across the life…
RT @h_okumura: ヒトの老化は、34歳、60歳、78歳で急激に進むことがわかった https://t.co/yAJIakUG6Z Undulating changes in human plasma proteome profiles across the life…
RT @h_okumura: ヒトの老化は、34歳、60歳、78歳で急激に進むことがわかった https://t.co/yAJIakUG6Z Undulating changes in human plasma proteome profiles across the life…
RT @h_okumura: ヒトの老化は、34歳、60歳、78歳で急激に進むことがわかった https://t.co/yAJIakUG6Z Undulating changes in human plasma proteome profiles across the life…
RT @h_okumura: ヒトの老化は、34歳、60歳、78歳で急激に進むことがわかった https://t.co/yAJIakUG6Z Undulating changes in human plasma proteome profiles across the life…
RT @h_okumura: ヒトの老化は、34歳、60歳、78歳で急激に進むことがわかった https://t.co/yAJIakUG6Z Undulating changes in human plasma proteome profiles across the life…
RT @h_okumura: ヒトの老化は、34歳、60歳、78歳で急激に進むことがわかった https://t.co/yAJIakUG6Z Undulating changes in human plasma proteome profiles across the life…
Undulating changes in human plasma proteome profiles across the lifespan. Lehallier B [..] Wyss-Coray T. Nat Med. 2019-12-05 (bioRxiv. 2019-09-01). https://t.co/Fv9POHzukk ".. identified three distinct time periods of change across the human life span"
Lehallier, B., Gate, D., Schaum, N. et al. Undulating changes in human plasma proteome profiles across the lifespan. Nat Med 25, 1843–1850 (2019) doi:10.1038/s41591-019-0673-2 @jpsenescence @AndreaBMaier @BertrandFougere @drjohnmorley @GeriSoc @britgerontology @livuniITM @MPUoL https://t.co/RgoV6fxIwE
Undulating changes in human plasma proteome profiles across the lifespan @wysscoray https://www.nature.com/articles/s41591-019-0673-2
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