Publications by authors named "David Gems"

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Interventions to Slow Aging in Humans: Are We Ready?
Valter D Longo, Adam Antebi, Andrzej Bartke, Nir Barzilai, Holly M Brown-Borg, Calogero Caruso, Tyler J Curiel, Rafael de Cabo, Claudio Franceschi, David Gems

August 2015

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Open problems in ageing science: a roadmap for biogerontology.
Angelo Talay, Aleksey V Belikov, Paul Ka Po To, Hamid H Alfatemi, Uri Alon, David Gems

Geroscience· November 2025

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Machine learning predicts lifespan and suggests underlying causes of death in aging C. elegans.
Carina C Kern, Petru Manescu, Matt Cuffaro, Catherine Au, Aihan Zhang, David Gems

Commun Biol· November 2025

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How aging causes osteoarthritis: An evolutionary physiology perspective.
David Gems

Osteoarthritis Cartilage· August 2025

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A hierarchy of causes of death in senescent .
Hongyuan Wang, Carina C Kern, Chiminh Nguyen Hong, Alis Saez Allende, Jiayi Qiao, David Gems

bioRxiv· August 2025

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Condition-dependent effects of knockdown of autophagy on longevity.
Kuei Ching Hsiung, Hannah Chapman, Xiaoya Wei, Xiaoyu Sun, Isadora Rawlinson, David Gems

bioRxiv· July 2025

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Characterization of Effects of mTOR Inhibitors on Aging in Caenorhabditis elegans.
Aihan Zhang, Gadea Meecham-Garcia, Chiminh Nguyen Hong, Peiyun Xie, Carina C Kern, David Gems

J Gerontol A Biol Sci Med Sci· November 2024

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Biological constraint, evolutionary spandrels and antagonistic pleiotropy.
David Gems, Carina C Kern

Ageing Res Rev· November 2024

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Epigenetic clocks and programmatic aging.
David Gems, Roop Singh Virk, João Pedro de Magalhães

Ageing Res Rev· November 2024

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Improved resilience and proteostasis mediate longevity upon DAF-2 degradation in old age.
Adrian Molière, Ji Young Cecilia Park, Anita Goyala, Elena M Vayndorf, Bruce Zhang, David Gems

Geroscience· October 2024

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Inflated expectations: the strange craze for translational research on aging : Given existing confusion about the basic science of aging, why the high optimism in the private sector about the prospects of developing anti-aging treatments?
David Gems, Simon Okholm, Maёl Lemoine

EMBO Rep· September 2024

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Colony level fitness analysis identifies a trade-off between population growth rate and dauer yield in Caenorhabditis elegans.
Hannah Chapman, Kuei Ching Hsiung, Isadora Rawlinson, Evgeniy R Galimov, David Gems

BMC Ecol Evol· January 2024

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Unraveling effects of anti-aging drugs on C. elegans using liposomes.
Aihan Zhang, Kuei Ching Hsiung, Carina C Kern, Yuting Wang, Anna L Girtle, David Gems

Geroscience· June 2023

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Is "cellular senescence" a misnomer?
David Gems, Carina C Kern

Geroscience· October 2022

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Guidelines for measuring reactive oxygen species and oxidative damage in cells and in vivo.
Michael P Murphy, Hülya Bayir, Vsevolod Belousov, Christopher J Chang, Kelvin J A Davies, David Gems

Nat Metab· June 2022

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Involving Young People in Healthy Ageing: A Crucial Facet to Achieving the Decade of Healthy Ageing (2021-2030).
Brian L H Wong, Ines Siepmann, Apoorva Rangan, Omnia El-Omrani, Daniel Davis, David Gems

Front Public Health· April 2022

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The hyperfunction theory: An emerging paradigm for the biology of aging.
David Gems

Ageing Res Rev· February 2022

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C. elegans feed yolk to their young in a form of primitive lactation.
Carina C Kern, StJohn Townsend, Antoine Salzmann, Nigel B Rendell, Graham W Taylor, David Gems

Nat Commun· October 2021

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The hoverfly and the wasp: A critique of the hallmarks of aging as a paradigm.
David Gems, João Pedro de Magalhães

Ageing Res Rev· September 2021

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Mitochondrial Signature in Human Monocytes and Resistance to Infection in During Fumarate-Induced Innate Immune Training.
C Angélica Pérez-Hernández, Carina C Kern, Egle Butkeviciute, Elizabeth McCarthy, Hazel M Dockrell, David Gems

Front Immunol· April 2021

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Death happy: adaptive ageing and its evolution by kin selection in organisms with colonial ecology.
Evgeniy R Galimov, David Gems

Philos Trans R Soc Lond B Biol Sci· April 2021

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Mutation of daf-2 extends lifespan via tissue-specific effectors that suppress distinct life-limiting pathologies.
Yuan Zhao, Bruce Zhang, Ioan Marcu, Faria Athar, Hongyuan Wang, David Gems

Aging Cell· March 2021

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Gross ways to live long: Parasitic worms as an anti-inflammaging therapy?
Bruce Zhang, David Gems

Elife· February 2021

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