Publications by authors named "David Gnutt"

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Self-supervision advances morphological profiling by unlocking powerful image representations.
Vladislav Kim, Nikolaos Adaloglou, Marc Osterland, Flavio M Morelli, Marah Halawa, David Gnutt

Sci Rep· February 2025

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Cell Painting unravels insecticidal modes of action on Spodoptera frugiperda insect cells.
Franziska A Hecker, Bruno Leggio, Tim König, Vladislav Kim, Marc Osterland, David Gnutt

Pestic Biochem Physiol· August 2024

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Intracellular spatially-targeted chemical chaperones increase native state stability of mutant SOD1 barrel.
Sara S Ribeiro, David Gnutt, Salome Azoulay-Ginsburg, Zamira Fetahaj, Ella Spurlock

Biol Chem· September 2023

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Optimizing the Cell Painting assay for image-based profiling.
Beth A Cimini, Srinivas Niranj Chandrasekaran, Maria Kost-Alimova, Lisa Miller, Amy Goodale, David Gnutt

Nat Protoc· July 2023

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Superoxide Dismutase 1 Folding Stability as a Target for Molecular Tweezers in SOD1-Related Amyotrophic Lateral Sclerosis.
Nirnay Samanta, Yasser B Ruiz-Blanco, Zamira Fetahaj, David Gnutt, Carter Lantz

Chembiochem· November 2022

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Cellular ATP Levels Determine the Stability of a Nucleotide Kinase.
Oliver Brylski, Puja Shrestha, Patricia Gnutt, David Gnutt, Jonathan Wolf Mueller

Front Mol Biosci· December 2021

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The Unfolding Journey of Superoxide Dismutase 1 Barrels under Crowding: Atomistic Simulations Shed Light on Intermediate States and Their Interactions with Crowders.
Stepan Timr, David Gnutt, Simon Ebbinghaus, Fabio Sterpone

J Phys Chem Lett· May 2020

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Effects of in vivo conditions on amyloid aggregation.
Michael C Owen, David Gnutt, Mimi Gao, Sebastian K T S Wärmländer, Jüri Jarvet

Chem Soc Rev· July 2019

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Protein Folding Modulation in Cells Subject to Differentiation and Stress.
David Gnutt, Linda Sistemich, Simon Ebbinghaus

Front Mol Biosci· May 2019

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Stability Effect of Quinary Interactions Reversed by Single Point Mutations.
David Gnutt, Stepan Timr, Jonas Ahlers, Benedikt König, Emily Manderfeld

J Am Chem Soc· March 2019

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Imperfect crowding adaptation of mammalian cells towards osmotic stress and its modulation by osmolytes.
David Gnutt, Oliver Brylski, Eugen Edengeiser, Martina Havenith, Simon Ebbinghaus

Mol Biosyst· October 2017

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Role of Electrostatics in Protein-RNA Binding: The Global vs the Local Energy Landscape.
Zhaleh Ghaemi, Irisbel Guzman, David Gnutt, Zaida Luthey-Schulten, Martin Gruebele

J Phys Chem B· September 2017

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Conformational dynamics and self-association of intrinsically disordered Huntingtin exon 1 in cells.
Steffen Büning, Abhishek Sharma, Shivang Vachharajani, Estella Newcombe, Angelique Ormsby, David Gnutt

Phys Chem Chem Phys· May 2017

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Inhibition of Huntingtin Exon-1 Aggregation by the Molecular Tweezer CLR01.
Tobias Vöpel, Kenny Bravo-Rodriguez, Sumit Mittal, Shivang Vachharajani, David Gnutt

J Am Chem Soc· April 2017

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RNA Hairpin Folding in the Crowded Cell.
Mimi Gao, David Gnutt, Axel Orban, Bettina Appel, Francesco Righetti

Angew Chem Int Ed Engl· February 2016

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The macromolecular crowding effect--from in vitro into the cell.
David Gnutt, Simon Ebbinghaus

Biol Chem· January 2016

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Excluded-volume effects in living cells.
David Gnutt, Mimi Gao, Oliver Brylski, Matthias Heyden, Simon Ebbinghaus

Angew Chem Int Ed Engl· February 2015

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