Publications by authors named "David Goertsen"

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Functional gene delivery to and across brain vasculature of systemic AAVs with endothelial-specific tropism in rodents and broad tropism in primates.
Xinhong Chen, Damien A Wolfe, Dhanesh Sivadasan Bindu, Mengying Zhang, Naz Taskin, David Goertsen, Timothy F Shay, Erin E Sullivan, Sheng-Fu Huang, Sripriya Ravindra Kumar

Nat Commun· June 2023

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Primate-conserved carbonic anhydrase IV and murine-restricted LY6C1 enable blood-brain barrier crossing by engineered viral vectors.
Timothy F Shay, Erin E Sullivan, Xiaozhe Ding, Xinhong Chen, Sripriya Ravindra Kumar, David Goertsen

Sci Adv· April 2023

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Functional gene delivery to and across brain vasculature of systemic AAVs with endothelial-specific tropism in rodents and broad tropism in primates.
Xinhong Chen, Damien A Wolfe, Dhanesh Sivadasan Bindu, Mengying Zhang, Naz Taskin, David Goertsen

bioRxiv· January 2023

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Targeting the lung epithelium after intravenous delivery by directed evolution of underexplored sites on the AAV capsid.
David Goertsen, Nick Goeden, Nicholas C Flytzanis, Viviana Gradinaru

Mol Ther Methods Clin Dev· September 2022

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Adeno-Associated Virus Toolkit to Target Diverse Brain Cells.
Rosemary C Challis, Sripriya Ravindra Kumar, Xinhong Chen, David Goertsen, Gerard M Coughlin

Annu Rev Neurosci· July 2022

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AAV capsid variants with brain-wide transgene expression and decreased liver targeting after intravenous delivery in mouse and marmoset.
David Goertsen, Nicholas C Flytzanis, Nick Goeden, Miguel R Chuapoco, Alexander Cummins

Nat Neurosci· January 2022

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