Publications by authors named "David Goldstone"

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Protease mimicry: Dissecting the ester bond crosslinking mechanics in bacterial adhesin proteins.
Yuliana Yosaatmadja, Vanessa Ung, Xinlu Liu, Yixuan Zhao, Julia K Wardega, David C Goldstone

Protein Sci· August 2025

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Medicago Mting1 Mting2 double knockout mutants are extremely dwarfed and never flower implicating essential MtING functions in growth and flowering.
Matthew Mayo-Smith, Axel Poulet, Lulu Zhang, Yongyan Peng, David Goldstone

BMC Plant Biol· April 2025

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"Pseudosubstrate Envelope"/Free Energy Perturbation-Guided Design and Mechanistic Investigations of Benzothiazole HIV Capsid Modulators with High Ligand Efficiency.
Shujing Xu, Shuo Wang, Yang Zhou, Nicholas Foley, Lin Sun, David C Goldstone

J Med Chem· November 2024

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Not All Binding Sites Are Equal: Site Determination and Folding State Analysis of Gas-Phase Protein-Metallodrug Adducts.
Liam Eade, Matthew P Sullivan, Timothy M Allison, David C Goldstone, Christian G Hartinger

Chemistry· May 2024

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AdductHunter: identifying protein-metal complex adducts in mass spectra.
Derek Long, Liam Eade, Matthew P Sullivan, Katharina Dost, Samuel M Meier-Menches, David C Goldstone

J Cheminform· February 2024

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Discovery, Crystallographic Studies, and Mechanistic Investigations of Novel Phenylalanine Derivatives Bearing a Quinazolin-4-one Scaffold as Potent HIV Capsid Modulators.
Shujing Xu, Lin Sun, Michael Barnett, Xujie Zhang, Dang Ding, David C Goldstone

J Med Chem· December 2023

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The (Mānuka)-Specific Nectar and Honey Compound 3,6,7-Trimethyllumazine (Lepteridine) That Inhibits Matrix Metalloproteinase 9 (MMP-9) Activity.
Bin Lin, Smitha Nair, Daniel M J Fellner, Noha Ahmed Nasef, Harjinder Singh, David C Goldstone

Foods· November 2023

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NlpC/P60 peptidoglycan hydrolases of Trichomonas vaginalis have complementary activities that empower the protozoan to control host-protective lactobacilli.
Michael J Barnett, Jully Pinheiro, Jeremy R Keown, Jacob Biboy, Joe Gray, David C Goldstone

PLoS Pathog· August 2023

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Platinum(terpyridine) complexes with N-heterocyclic carbene co-ligands: high antiproliferative activity and low toxicity .
Matthew P Sullivan, Muneebah Adams, Mie Riisom, Caitlin D Herbert, Kelvin K H Tong, David C Goldstone

Dalton Trans· January 2023

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MtING2 encodes an ING domain PHD finger protein which affects Medicago growth, flowering, global patterns of H3K4me3, and gene expression.
Mauren Jaudal, Matthew Mayo-Smith, Axel Poulet, Annabel Whibley, Yongyan Peng, David C Goldstone

Plant J· November 2022

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Mapping the interaction between Trim28 and the KRAB domain at the center of Trim28 silencing of endogenous retroviruses.
Jamie R H Taka, Yunyuan Sun, David C Goldstone

Protein Sci· October 2022

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Anthracenyl Functionalization of Half-Sandwich Carbene Complexes: Anticancer Activity and Reactions with Biomolecules.
Betty Y T Lee, Matthew P Sullivan, Ena Yano, Kelvin K H Tong, Muhammad Hanif, David C Goldstone

Inorg Chem· October 2021

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Probing the Paradigm of Promiscuity for N-Heterocyclic Carbene Complexes and their Protein Adduct Formation.
Matthew P Sullivan, Monika Cziferszky, Iogann Tolbatov, Dianna Truong, Davide Mercadante, David C Goldstone

Angew Chem Int Ed Engl· September 2021

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Structural Analysis of the Menangle Virus P Protein Reveals a Soft Boundary between Ordered and Disordered Regions.
Melissa N Webby, Nicole Herr, Esther M M Bulloch, Michael Schmitz, Jeremy R Keown, David C Goldstone

Viruses· August 2021

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Mustards-Derived Terpyridine-Platinum Complexes as Anticancer Agents: DNA Alkylation vs Coordination.
Muneebah Adams, Matthew P Sullivan, Kelvin K H Tong, David C Goldstone, Muhammad Hanif

Inorg Chem· February 2021

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Granulovirus PK-1 kinase activity relies on a side-to-side dimerization mode centered on the regulatory αC helix.
Michael R Oliver, Christopher R Horne, Safal Shrestha, Jeremy R Keown, Lung-Yu Liang, David C Goldstone

Nat Commun· February 2021

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Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition).
Daniel J Klionsky, Amal Kamal Abdel-Aziz, Sara Abdelfatah, Mahmoud Abdellatif, Asghar Abdoli, David C Goldstone

Autophagy· January 2021

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A Combined Spectroscopic and Protein Crystallography Study Reveals Protein Interactions of Rh(NHC) Complexes at the Molecular Level.
Isabelle M Daubit, Matthew P Sullivan, Milena John, David C Goldstone, Christian G Hartinger

Inorg Chem· December 2020

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The RING domain of TRIM69 promotes higher-order assembly.
Jeremy R Keown, Joy Yang, Moyra M Black, David C Goldstone

Acta Crystallogr D Struct Biol· October 2020

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Potent Inhibition of Thioredoxin Reductase by the Rh Derivatives of Anticancer M(arene/Cp*)(NHC)Cl Complexes.
Dianna Truong, Matthew P Sullivan, Kelvin K H Tong, Tasha R Steel, Andre Prause, David C Goldstone

Inorg Chem· March 2020

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Structural basis for Fullerene geometry in a human endogenous retrovirus capsid.
Oliver Acton, Tim Grant, Giuseppe Nicastro, Neil J Ball, David C Goldstone

Nat Commun· December 2019

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Gel electrophoresis in combination with laser ablation-inductively coupled plasma mass spectrometry to quantify the interaction of cisplatin with human serum albumin.
Matthew P Sullivan, Stuart J Morrow, David C Goldstone, Christian G Hartinger

Electrophoresis· September 2019

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A Dissection of Oligomerization by the TRIM28 Tripartite Motif and the Interaction with Members of the Krab-ZFP Family.
Yunyuan Sun, Jeremy R Keown, Moyra M Black, Charlène Raclot, Nicholas Demarais, David C Goldstone

J Mol Biol· June 2019

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Crystal structure of protein tyrosine phosphatase-2 from Cydia pomonella granulovirus.
Guangmei Huang, Michael R Oliver, Jeremy R Keown, David C Goldstone, Peter Metcalf

Acta Crystallogr F Struct Biol Commun· April 2019

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Correction: Unexpected arene ligand exchange results in the oxidation of an organoruthenium anticancer agent: the first X-ray structure of a protein-Ru(carbene) adduct.
Matthew P Sullivan, Michél K Nieuwoudt, Graham A Bowmaker, Nelson Y S Lam, Dianna Truong, David C Goldstone

Chem Commun (Camb)· January 2019

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