Publications by authors named "David H Small"

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Alzheimer's amyloid-β and tau protein accumulation is associated with decreased expression of the LDL receptor-associated protein in human brain tissue.
Claire E Shepherd, Andrew J Affleck, Anita Y Bahar, Francine Carew-Jones, Gillian Gregory, David H Small

Brain Behav· July 2020

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Knockout of Amyloid β Protein Precursor (APP) Expression Alters Synaptogenesis, Neurite Branching and Axonal Morphology of Hippocampal Neurons.
Katherine A Southam, Fiona Stennard, Cassandra Pavez, David H Small

Neurochem Res· June 2019

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Peripheral treatment with enoxaparin exacerbates amyloid plaque pathology in Tg2576 mice.
Hao Cui, Anna E King, Glenn A Jacobson, David H Small

J Neurosci Res· April 2017

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Do Microglia Default on Network Maintenance in Alzheimer's Disease?
Katherine A Southam, Adele J Vincent, David H Small

J Alzheimers Dis· December 2016

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Corrigendum: N-terminal domain of Bothrops asper Myotoxin II Enhances the Activity of Endothelin Converting Enzyme-1 and Neprilysin.
A Ian Smith, Niwanthi W Rajapakse, Oded Kleifeld, Bruno Lomonte, Nkumbu L Sikanyika, David H Small

Sci Rep· April 2016

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N-terminal domain of Bothrops asper Myotoxin II Enhances the Activity of Endothelin Converting Enzyme-1 and Neprilysin.
A Ian Smith, Niwanthi W Rajapakse, Oded Kleifeld, Bruno Lomonte, Nkumbu L Sikanyika, David H Small

Sci Rep· March 2016

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The N-terminal fragment of the β-amyloid precursor protein of Alzheimer's disease (N-APP) binds to phosphoinositide-rich domains on the surface of hippocampal neurons.
Edgar Dawkins, Robert Gasperini, Yanling Hu, Hao Cui, Adele J Vincent, David H Small

J Neurosci Res· November 2014

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Neurogenin 2 mediates amyloid-β precursor protein-stimulated neurogenesis.
Marta Bolós, Yanling Hu, Kaylene M Young, Lisa Foa, David H Small

J Biol Chem· November 2014

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β-Amyloid precursor protein: function in stem cell development and Alzheimer's disease brain.
David H Small, Yanling Hu, Marta Bolós, Edgar Dawkins, Lisa Foa

Neurodegener Dis· September 2014

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Insights into the physiological function of the β-amyloid precursor protein: beyond Alzheimer's disease.
Edgar Dawkins, David H Small

J Neurochem· June 2014

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Mechanisms of transthyretin aggregation and toxicity.
Robert J Gasperini, David W Klaver, Xu Hou, Marie-Isabel Aguilar, David H Small

Subcell Biochem· February 2014

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Role of cystatin C in amyloid precursor protein-induced proliferation of neural stem/progenitor cells.
Yanling Hu, Amos C Hung, Hao Cui, Edgar Dawkins, Marta Bolós, David H Small

J Biol Chem· June 2013

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Proteoglycans in the central nervous system: role in development, neural repair, and Alzheimer's disease.
Hao Cui, Craig Freeman, Glenn A Jacobson, David H Small

IUBMB Life· February 2013

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Size and sulfation are critical for the effect of heparin on APP processing and Aβ production.
Hao Cui, Amos C Hung, Craig Freeman, Christian Narkowicz, Glenn A Jacobson, David H Small

J Neurochem· November 2012

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STIM1 is necessary for store-operated calcium entry in turning growth cones.
Camilla B Mitchell, Robert J Gasperini, David H Small, Lisa Foa

J Neurochem· September 2012

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Neurodegeneration in familial amyloidotic polyneuropathy.
Robert J Gasperini, David H Small

Clin Exp Pharmacol Physiol· August 2012

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Dysregulation of Ca2+ homeostasis in Alzheimer's disease: role in acetylcholinesterase production and AMPA receptor internalization.
David H Small

Neurodegener Dis· August 2012

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Targeting pre-mRNA splicing: a BACE-ic strategy for AD drug development?
David H Small, Marie-Isabel Aguilar

J Neurochem· June 2012

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Altered expression of brain acetylcholinesterase in FTDP-17 human tau transgenic mice.
María-Ximena Silveyra, María-Salud García-Ayllón, Elena Gómez de Barreda, David H Small, Salvador Martínez

Neurobiol Aging· March 2012

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Characterization of early stage intermediates in the nucleation phase of Aβ aggregation.
Jiali Zhai, Tzong-Hsien Lee, David H Small, Marie-Isabel Aguilar

Biochemistry· February 2012

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Effects of heparin and enoxaparin on APP processing and Aβ production in primary cortical neurons from Tg2576 mice.
Hao Cui, Amos C Hung, David W Klaver, Toshiharu Suzuki, Craig Freeman, David H Small

PLoS One· December 2011

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Revisiting the Role of Acetylcholinesterase in Alzheimer's Disease: Cross-Talk with P-tau and β-Amyloid.
María-Salud García-Ayllón, David H Small, Jesús Avila, Javier Sáez-Valero

Front Mol Neurosci· November 2011

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Surface plasmon resonance spectroscopy: a new lead in studying the membrane binding of amyloidogenic transthyretin.
Xu Hou, David H Small, Marie-Isabel Aguilar

Methods Mol Biol· October 2011

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Astrocytes in Alzheimer's disease: emerging roles in calcium dysregulation and synaptic plasticity.
Adele J Vincent, Robert Gasperini, Lisa Foa, David H Small

J Alzheimers Dis· June 2011

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TRPM8 and Nav1.8 sodium channels are required for transthyretin-induced calcium influx in growth cones of small-diameter TrkA-positive sensory neurons.
Robert J Gasperini, Xu Hou, Helena Parkington, Harry Coleman, David W Klaver, David H Small

Mol Neurodegener· March 2011

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