Publications by authors named "David Hein"

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Clinical Pharmacogenetics Implementation Consortium Guideline for NAT2 Genotype and Hydralazine Therapy.
Michael T Eadon, David W Hein, Michael A Andersen, Arlene B Chapman, Rhonda M Cooper-DeHoff

Clin Pharmacol Ther· December 2025

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Arylamine N-Acetyltransferase 1 Knockout in Immortalized Human Bronchial Cells Results in a Reduction of Cellular Growth.
Sandra S Diven, Kate Tarvestad-Laise, David W Hein, James T F Wise

Gene Rep· December 2025

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Correction: Effect of N‑acetyltransferase 2 genetic polymorphism on 4,4'‑methylenebis(2‑chloroaniline)‑induced genotoxicity and oxidative stress.
Mariam R Habil, Raúl A Salazar-González, Mark A Doll, David W Hein

Arch Toxicol· December 2025

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Resolving phenotyping discordance with SPACEMAP, an integrated machine learning framework.
Bassel Dawod, Arely Perez Rodriguez, Sebastian Diegeler, Eslam A Elghonaimy, Megan Wachsman, David Hein

bioRxiv· December 2025

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Physical Examination Identification in Medical Education Videos: Zero-Shot Multimodal AI With Temporal Sequence Optimization Study.
Shinyoung Kang, Michael Holcomb, David Hein, Ameer Hamza Shakur, Thomas Dalton

JMIR AI· December 2025

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PharmVar GeneFocus: NAT2-Genetic Variation and Updated Nomenclature.
Georgia Papanikolaou, Estella S Poloni, José A G Agúndez, Raquel L F Teixeira, Erin C Boone, David W Hein

Clin Pharmacol Ther· December 2025

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Mini-review: Human N-acetyltransferase genetic polymorphisms in susceptibility to aromatic amine and alkylaniline genotoxicity.
Mariam R Habil, David W Hein

J Pharmacol Exp Ther· September 2025

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Report on the 2024 international phase II/N-acetyltransferase workshop.
David W Hein

Arch Toxicol· August 2025

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Metabolic effects of heterocyclic amines on insulin‑induced AKT phosphorylation and gluconeogenic gene expression are modified by N -acetyltransferase 2 genetic polymorphism.
Kennedy M Walls, Jonathan Y Joh, Madeline M Martinez, Kyung U Hong, David W Hein

Pharmacogenet Genomics· June 2025

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Metabolism and genotoxicity of 4,4'-oxydianiline is dependent on N-acetyltransferase 2 genetic polymorphism.
Raul A Salazar-González, James T F Wise, Mark A Doll, David W Hein

Environ Toxicol Pharmacol· June 2025

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Benchmarks of success in radiotherapy vs systemic therapy: National Clinical Trials Network (NCTN) randomized controlled trials sponsored by the National Cancer Institute (NCI).
Nina N Sanford, Qian Shi, David M Hein, William A Hall

J Natl Cancer Inst· May 2025

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Iterative refinement and goal articulation to optimize large language models for clinical information extraction.
David Hein, Alana Christie, Michael Holcomb, Bingqing Xie, A J Jain

NPJ Digit Med· May 2025

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Prompts to Table: Specification and Iterative Refinement for Clinical Information Extraction with Large Language Models.
David Hein, Alana Christie, Michael Holcomb, Bingqing Xie, A J Jain

medRxiv· April 2025

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Recurrence-free survival prediction for anal squamous cell carcinoma after chemoradiotherapy using planning CT-based radiomics model.
Shanshan Tang, Kai Wang, David Hein, Gloria Lin, Nina N Sanford

Br J Radiol· February 2025

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Does a Provider Contact Wristband Reduce Emergency Department Visit Rates Following Hip or Knee Arthroplasty?
David C Hein, Ajay K Srivastava, Seann E Willson, Paul M Telehowski, Patrick J Atkinson

Arthroplast Today· February 2025

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Bioactivation, Mutagenicity, DNA Damage, and Oxidative Stress Induced by 3,4-Dimethylaniline.
Mariam R Habil, Raúl A Salazar-González, Mark A Doll, David W Hein

Biomolecules· December 2024

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Investigation on regulation of -acetyltransferase 2 expression by nuclear receptors in human hepatocytes.
Kyung U Hong, Anthony P Aureliano, Kennedy M Walls, David W Hein

Front Pharmacol· November 2024

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Heterocyclic Amines Disrupt Lipid Homeostasis in Cryopreserved Human Hepatocytes.
Kennedy M Walls, Jonathan Y Joh, Kyung U Hong, David W Hein

Cardiovasc Toxicol· August 2024

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Association of genetic ancestry with molecular tumor profiles in colorectal cancer.
Brooke Rhead, David M Hein, Yannick Pouliot, Justin Guinney, Francisco M De La Vega

Genome Med· August 2024

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Assessment of Distinct Gut Microbiome Signatures in a Diverse Cohort of Patients Undergoing Definitive Treatment for Rectal Cancer.
David M Hein, Laura A Coughlin, Nicole Poulides, Andrew Y Koh, Nina N Sanford

J Immunother Precis Oncol· August 2024

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N-acetyltransferase metabolism and DNA damage following exposure to 4,4'-oxydianiline in human bronchial epithelial cells.
James T F Wise, David W Hein

Toxicol Lett· July 2024

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Screening Implications for Distribution of Colorectal Cancer Subsite by Age and Role of Flexible Sigmoidoscopy.
Gloria Lin, David M Hein, Po-Hong Liu, Amit G Singal, Nina N Sanford

Cancers (Basel)· March 2024

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Correction: Heterocyclic amines reduce insulin-induced AKT phosphorylation and induce gluconeogenic gene expression in human hepatocytes.
Kennedy M Walls, Kyung U Hong, David W Hein

Arch Toxicol· November 2023

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The effect of the rs1799931 G857A (G286E) polymorphism on N-acetyltransferase 2-mediated carcinogen metabolism and genotoxicity differs with heterocyclic amine exposure.
David W Hein, Raúl A Salazar-González, Mark A Doll, Yu Zang

Arch Toxicol· October 2023

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Screening Implications for Distribution of Colorectal Cancer Subsite by Age.
Gloria Lin, David M Hein, Po-Hong Liu, Amit G Singal, Nina N Sanford

medRxiv· July 2023

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