Publications by authors named "David Hottman"

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The HDL-Mimetic Peptide 4F Mitigates Vascular and Cortical Amyloid Pathology and Associated Neuroinflammation in a Transgenic Mouse Model of Cerebral Amyloid Angiopathy and Alzheimer's Disease.
Rui Zhong, Dustin Chernick, David Hottman, Yejun Tan, Minwoo Kim

Mol Neurobiol· August 2025

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Targeting senescent stemlike subpopulations in Philadelphia chromosome-like acute lymphoblastic leukemia.
Yang-Yang Ding, Jonathan H Sussman, Kellyn Madden, Joseph P Loftus, Robert K Chen, David A Hottman

Blood· March 2025

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Modulation of CD22 Protein Expression in Childhood Leukemia by Pervasive Splicing Aberrations: Implications for CD22-Directed Immunotherapies.
Sisi Zheng, Elisabeth Gillespie, Ammar S Naqvi, Katharina E Hayer, Zhiwei Ang, David A Hottman

Blood Cancer Discov· March 2022

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Therapeutic potential of ruxolitinib and ponatinib in patients with -rearranged Philadelphia chromosome-like acute lymphoblastic leukemia.
Lisa M Niswander, Joseph P Loftus, Élodie Lainey, Aurélie Caye-Eude, Morgane Pondrom, David A Hottman

Haematologica· October 2021

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Neuronal Protein Farnesylation Regulates Hippocampal Synaptic Plasticity and Cognitive Function.
Wenhui Qu, Kiall F Suazo, Wenfeng Liu, Shaowu Cheng, Angela Jeong, David Hottman

Mol Neurobiol· March 2021

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Systemic or Forebrain Neuron-Specific Deficiency of Geranylgeranyltransferase-1 Impairs Synaptic Plasticity and Reduces Dendritic Spine Density.
David Hottman, Shaowu Cheng, Andrea Gram, Kyle LeBlanc, Li-Lian Yuan

Neuroscience· March 2018

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Haplodeficiency of Cathepsin D does not affect cerebral amyloidosis and autophagy in APP/PS1 transgenic mice.
Shaowu Cheng, Willayat Y Wani, David A Hottman, Angela Jeong, Dongfeng Cao

J Neurochem· July 2017

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HDL and cognition in neurodegenerative disorders.
David A Hottman, Dustin Chernick, Shaowu Cheng, Zhe Wang, Ling Li

Neurobiol Dis· December 2014

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Protein prenylation and synaptic plasticity: implications for Alzheimer's disease.
David A Hottman, Ling Li

Mol Neurobiol· August 2014

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Simvastatin treatment enhances NMDAR-mediated synaptic transmission by upregulating the surface distribution of the GluN2B subunit.
Marc-Alexander L T Parent, David A Hottman, Shaowu Cheng, Wei Zhang, Lori L McMahon

Cell Mol Neurobiol· July 2014

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Farnesyltransferase haplodeficiency reduces neuropathology and rescues cognitive function in a mouse model of Alzheimer disease.
Shaowu Cheng, Dongfeng Cao, David A Hottman, LiLian Yuan, Martin O Bergo

J Biol Chem· December 2013

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