Publications by authors named "David Hum"

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Human OTULIN haploinsufficiency impairs cell-intrinsic immunity to staphylococcal α-toxin.
András N Spaan, Anna-Lena Neehus, Emmanuel Laplantine, Frederik Staels, Masato Ogishi, David Hum, Stéphanie Humblet-Baron

Science· June 2022

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Biochemically deleterious human NFKB1 variants underlie an autosomal dominant form of common variable immunodeficiency.
Juan Li, Wei-Te Lei, Peng Zhang, Franck Rapaport, Yoann Seeleuthner, David Hum

J Exp Med· November 2021

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Human STAT3 variants underlie autosomal dominant hyper-IgE syndrome by negative dominance.
Takaki Asano, Joëlle Khourieh, Peng Zhang, Franck Rapaport, András N Spaan, David Hum

J Exp Med· August 2021

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Fatal Cytomegalovirus Infection in an Adult with Inherited NOS2 Deficiency.
Scott B Drutman, Davood Mansouri, Seyed Alireza Mahdaviani, Anna-Lena Neehus, David Hum

N Engl J Med· January 2020

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Homozygous gain-of-function mutation in siblings with a syndromic form of recurrent respiratory papillomatosis.
Scott B Drutman, Filomeen Haerynck, Franklin L Zhong, David Hum, Nicholas J Hernandez

Proc Natl Acad Sci U S A· September 2019

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The human CIB1-EVER1-EVER2 complex governs keratinocyte-intrinsic immunity to β-papillomaviruses.
Sarah Jill de Jong, Amandine Créquer, Irina Matos, David Hum, Vignesh Gunasekharan

J Exp Med· September 2018

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The unfolded protein response genes in human osteoarthritic chondrocytes: PERK emerges as a potential therapeutic target.
Ying-Hua Li, Ginette Tardif, David Hum, Mohit Kapoor, Hassan Fahmi

Arthritis Res Ther· July 2016

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Cartilage-specific deletion of ephrin-B2 in mice results in early developmental defects and an osteoarthritis-like phenotype during aging in vivo.
Gladys Valverde-Franco, Bertrand Lussier, David Hum, Jiangping Wu, Adjia Hamadjida

Arthritis Res Ther· March 2016

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The in vivo effect of prophylactic subchondral bone protection of osteoarthritic synovial membrane in bone-specific Ephb4-overexpressing mice.
Gladys Valverde-Franco, David Hum, Koichi Matsuo, Bertrand Lussier, Jean-Pierre Pelletier

Am J Pathol· February 2015

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NFAT3 and TGF-β/SMAD3 regulate the expression of miR-140 in osteoarthritis.
Ginette Tardif, Jean-Pierre Pelletier, Hassan Fahmi, David Hum, Yue Zhang

Arthritis Res Ther· November 2014

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In vivo bone-specific EphB4 overexpression in mice protects both subchondral bone and cartilage during osteoarthritis.
Gladys Valverde-Franco, Jean-Pierre Pelletier, Hassan Fahmi, David Hum, Koichi Matsuo

Arthritis Rheum· November 2012

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Regulation of the IGFBP-5 and MMP-13 genes by the microRNAs miR-140 and miR-27a in human osteoarthritic chondrocytes.
Ginette Tardif, David Hum, Jean-Pierre Pelletier, Nicolas Duval, Johanne Martel-Pelletier

BMC Musculoskelet Disord· November 2009

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Ultrabroadband biphotons generated via chirped quasi-phase-matched optical parametric down-conversion.
Magued B Nasr, Silvia Carrasco, Bahaa E A Saleh, Alexander V Sergienko, Malvin C Teich, David S Hum

Phys Rev Lett· May 2008

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Linearly polarized, 3.35 W narrow-linewidth, 1150 nm fiber master oscillator power amplifier for frequency doubling to the yellow.
Supriyo Sinha, Karel E Urbanek, David S Hum, Michel J F Digonnet, Martin M Fejer

Opt Lett· June 2007

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Identification in human osteoarthritic chondrocytes of proteins binding to the novel regulatory site AGRE in the human matrix metalloprotease 13 proximal promoter.
Zhiyong Fan, Ginette Tardif, Christelle Boileau, Joseph P Bidwell, Changshan Geng, David Hum

Arthritis Rheum· August 2006

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Differential gene expression and regulation of the bone morphogenetic protein antagonists follistatin and gremlin in normal and osteoarthritic human chondrocytes and synovial fibroblasts.
Ginette Tardif, David Hum, Jean-Pierre Pelletier, Christelle Boileau, Pierre Ranger

Arthritis Rheum· August 2004

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Characterization of a cGMP-response element in the guanylyl cyclase/natriuretic peptide receptor A gene promoter.
David Hum, Sandrine Besnard, Rocio Sanchez, Dominic Devost, Francis Gossard

Hypertension· June 2004

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TA repeat variation, Npr1 expression, and blood pressure: impact of the Ace locus.
Johanne Tremblay, David H F Hum, Rocio Sanchez, Pierre Dumas, Michal Pravenec

Hypertension· January 2003

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Biochemistry and physiology of the natriuretic peptide receptor guanylyl cyclases.
Johanne Tremblay, Richard Desjardins, David Hum, Jolanta Gutkowska, Pavel Hamet

Mol Cell Biochem· January 2002

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