Publications by authors named "David Issadore"

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Microgel Aspect Ratio Influences Injectable Granular Hydrogel Scaffold Pore Structure and Cellular Invasion for Tissue Repair.
Gabriel J Rodriguez-Rivera, Siddharth Sharma, Chima V Maduka, Sara Boyd, Amy R Perry, David Issadore

Adv Sci (Weinh)· November 2025

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Scalable flow synthesis of ultrasmall inorganic nanoparticles for biomedical applications a confined impinging jet mixer.
Andrea C Kian, Mahima Gupta, Heeju Hong, Kálery La Luz Rivera, Nil Pandey, David Issadore

bioRxiv· November 2025

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Elucidating lipid nanoparticle properties and structure through biophysical analyses.
Marshall S Padilla, Sarah J Shepherd, Andrew R Hanna, Martin Kurnik, Xujun Zhang, David Issadore

bioRxiv· October 2025

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Elucidating lipid nanoparticle properties and structure through biophysical analyses.
Marshall S Padilla, Sarah J Shepherd, Andrew R Hanna, Martin Kurnik, Xujun Zhang, David Issadore

Nat Biotechnol· October 2025

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Brain biomarker profiles vary with semi-synthetic and grain-based diets in healthy and mTBI mice.
Erin D Anderson, Daunel V Augustin, Anastasia P Georges, David A Issadore, David F Meaney

Neurosci Lett· September 2025

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Extracellular Vesicles for Clinical Diagnostics: From Bulk Measurements to Single-Vesicle Analysis.
Hai Linh Tran, Wenshu Zheng, David A Issadore, Hyungsoon Im, Yoon-Kyoung Cho

ACS Nano· August 2025

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Mechanical regulation of extracellular vesicle activity during tumour progression.
Kshitiz Parihar, Di-Ao Liu, Ghmkin Hassan, David A Issadore, Paul A Janmey

Nat Biomed Eng· August 2025

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Brain-derived extracellular vesicle microRNAs in Lewy body and Alzheimer's disease.
Stephanie J Yang, Andrew A Lin, Hanfei Shen, Laura W Pappalardo, Griffin B Spychalski, David Issadore

bioRxiv· June 2025

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Agarose Microgel-Based In Situ Cleavable Immuno-Rolling Circle Amplification for Multiplexed Single-Molecule Quantitation on Single Extracellular Vesicles.
Juhwan Park, Michelle Feng, Jingbo Yang, Hanfei Shen, Zhiyuan Qin, David A Issadore

ACS Nano· May 2025

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Combining time domain modulation optofluidics and high dynamic range imaging for multiplexed, high throughput digital droplet assays.
Yasemin Atiyas, Michael J Siedlik, Stephanie J Yang, David A Issadore

Microsyst Nanoeng· May 2025

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miRNA panel from HER2+ and CD24+ plasma extracellular vesicle subpopulations as biomarkers of early-stage breast cancer.
Griffin B Spychalski, Andrew A Lin, Stephanie J Yang, Hanfei Shen, Jean Rosario, David Issadore

Breast Cancer Res· May 2025

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Automated and parallelized microfluidic generation of large and precisely-defined lipid nanoparticle libraries.
Andrew R Hanna, Sarah J Shepherd, Gregory A Datto, Isabel B Navarro, Adele S Ricciardi, David A Issadore

bioRxiv· May 2025

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Towards the clinical translation of a silver sulfide nanoparticle contrast agent: large scale production with a highly parallelized microfluidic chip.
Katherine J Mossburg, Sarah J Shepherd, Diego Barragan, Nathaniel H O, Emily K Berkow, David Issadore

Eur J Nucl Med Mol Imaging· February 2025

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Multi-stage-mixing to control the supramolecular structure of lipid nanoparticles, thereby creating a core-then-shell arrangement that improves performance by orders of magnitude.
Jia Nong, Xijing Gong, Quang Minh Dang, Sachchidanand Tiwari, Manthan Patel, David Issadore

bioRxiv· February 2025

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Robust, Scalable Microfluidic Manufacturing of RNA-Lipid Nanoparticles Using Immobilized Antifouling Lubricant Coating.
Yoon-Ho Hwang, Sarah J Shepherd, Dongyoon Kim, Alvin J Mukalel, Michael J Mitchell, David A Issadore

ACS Nano· January 2025

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Enhanced Accumulation and Penetration of Magnetic Nanoclusters in Tumors Using an 8-Magnet Halbach Array Leads to Improved Cancer Treatment.
Bian Jang, Ahmad Amirshaghaghi, Jeongmoon Choi, Joann Miller, David A Issadore

ACS Nano· January 2025

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High-throughput, multiplexed quantification, and sorting of single EVs at single-molecule level.
Juhwan Park, Michelle Feng, Jingbo Yang, Hanfei Shen, Zhiyuan Qin, David A Issadore

bioRxiv· November 2024

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Ultrasensitive quantification of PD-L1+ extracellular vesicles in melanoma patient plasma using a parallelized high throughput droplet digital assay.
Hanfei Shen, Yasemin Atiyas, Zijian Yang, Andrew A Lin, Jingbo Yang, David A Issadore

Lab Chip· July 2024

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Mitigation of Device Heterogeneity in Graphene Hall Sensor Arrays Using Per-Element Backgate Tuning.
Vasant Iyer, Alan T Charlie Johnson, Firooz Aflatouni, David A Issadore

ACS Appl Mater Interfaces· July 2024

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Single-mitochondrion sequencing uncovers distinct mutational patterns and heteroplasmy landscape in mouse astrocytes and neurons.
Parnika S Kadam, Zijian Yang, Youtao Lu, Hua Zhu, Yasemin Atiyas, David Issadore

BMC Biol· July 2024

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Single-Mitochondrion Sequencing Uncovers Distinct Mutational Patterns and Heteroplasmy Landscape in Mouse Astrocytes and Neurons.
Parnika S Kadam, Zijian Yang, Youtao Lu, Hua Zhu, Yasemin Atiyas, David Issadore

bioRxiv· June 2024

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High-Throughput Single-Cell, Single-Mitochondrial DNA Assay Using Hydrogel Droplet Microfluidics.
Juhwan Park, Parnika S Kadam, Yasemin Atiyas, Bonirath Chhay, Andrew Tsourkas, David A Issadore

Angew Chem Int Ed Engl· April 2024

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Microfluidic Generation of Diverse Lipid Nanoparticle Libraries.
Andrew R Hanna, Sarah J Shepherd, David Issadore, Michael J Mitchell

Nanomedicine (Lond)· March 2024

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High-throughput single-cell, single-mitochondrial DNA assay using hydrogel droplet microfluidics.
Juhwan Park, Parnika S Kadam, Yasemin Atiyas, Bonirath Chhay, Andrew Tsourkas, David A Issadore

bioRxiv· January 2024

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Towards the Clinical Translation of a Silver Sulfide Nanoparticle Contrast Agent: Large Scale Production with a Highly Parallelized Microfluidic Chip.
Katherine J Mossburg, Sarah J Shepherd, Diego Barragan, Nathaniel H O, Emily K Berkow, David Issadore

bioRxiv· December 2023

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