Publications by authors named "David J Fear"

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Inhibition of PI3K p110δ activity reduces IgE production in IL-4 and anti-CD40 stimulated human B cell cultures.
Anna Cutrina-Pons, Aloka De Sa, David J Fear, Hannah J Gould, Faruk Ramadani

Immunology· December 2023

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SARS-CoV-2-Specific Memory B Cell Responses Are Maintained After Recovery from Natural Infection and Postvaccination.
Tom Moore, Rojony Hossain, Katie J Doores, Manu Shankar-Hari, David J Fear

Viral Immunol· July 2022

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Human marginal zone B cell development from early T2 progenitors.
Thomas J Tull, Michael J Pitcher, William Guesdon, Jacqueline H Y Siu, Cristina Lebrero-Fernández, David J Fear

J Exp Med· April 2021

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Altered chromatin landscape in circulating T follicular helper and regulatory cells following grass pollen subcutaneous and sublingual immunotherapy.
Hanisah Sharif, Swati Acharya, Gopal Krishna R Dhondalay, Gilda Varricchi, Shoshanna Krasner-Macleod, David J Fear

J Allergy Clin Immunol· February 2021

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Transcriptional Analysis of the Human IgE-Expressing Plasma Cell Differentiation Pathway.
Faruk Ramadani, Holly Bowen, Hannah J Gould, David J Fear

Front Immunol· June 2020

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miR-29b directly targets activation-induced cytidine deaminase in human B cells and can limit its inappropriate expression in naïve B cells.
Timothy Recaldin, Philip S Hobson, Elizabeth H Mann, Faruk Ramadani, David J Cousins, David J Fear

Mol Immunol· September 2018

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Spatiotemporal segregation of human marginal zone and memory B cell populations in lymphoid tissue.
Yuan Zhao, Mohamed Uduman, Jacqueline H Y Siu, Thomas J Tull, Jeremy D Sanderson, David J Fear

Nat Commun· September 2018

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Global gene regulation during activation of immunoglobulin class switching in human B cells.
Youming Zhang, David J Fear, Saffron A G Willis-Owen, William O Cookson, Miriam F Moffatt

Sci Rep· November 2016

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IgG subclass switching and clonal expansion in cutaneous melanoma and normal skin.
Louise Saul, Kristina M Ilieva, Heather J Bax, Panagiotis Karagiannis, Isabel Correa, David J Fear

Sci Rep· July 2016

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Mechanisms regulating the targeting and activity of activation induced cytidine deaminase.
David J Fear

Curr Opin Immunol· October 2013

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Comprehensive FISH probe design tool applied to imaging human immunoglobulin class switch recombination.
Jakub Nedbal, Philip S Hobson, David J Fear, Rainer Heintzmann, Hannah J Gould

PLoS One· June 2013

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IgG4 subclass antibodies impair antitumor immunity in melanoma.
Panagiotis Karagiannis, Amy E Gilbert, Debra H Josephs, Niwa Ali, Tihomir Dodev, David J Fear

J Clin Invest· April 2013

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Soluble CD23 controls IgE synthesis and homeostasis in human B cells.
Alison M Cooper, Philip S Hobson, Mark R Jutton, Michael W Kao, Binia Drung, David J Fear

J Immunol· April 2012

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High resolution analysis of the chromatin landscape of the IgE switch region in human B cells.
Sandeep Dayal, Jakub Nedbal, Philip Hobson, Alison M Cooper, Hannah J Gould, David J Fear

PLoS One· February 2012

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Analysis of intergenic transcription and histone modification across the human immunoglobulin heavy-chain locus.
Muslima Chowdhury, Omid Forouhi, Sandeep Dayal, Natalie McCloskey, Hannah J Gould, David J Fear

Proc Natl Acad Sci U S A· October 2008

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IgE-antibody-dependent immunotherapy of solid tumors: cytotoxic and phagocytic mechanisms of eradication of ovarian cancer cells.
Sophia N Karagiannis, Marguerite G Bracher, James Hunt, Natalie McCloskey, Rebecca L Beavil, David J Fear

J Immunol· September 2007

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Soluble CD23 monomers inhibit and oligomers stimulate IGE synthesis in human B cells.
Natalie McCloskey, James Hunt, Rebecca L Beavil, Mark R Jutton, Gabrielle J Grundy, David J Fear

J Biol Chem· August 2007

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Allergen drives class switching to IgE in the nasal mucosa in allergic rhinitis.
Pooja Takhar, Lyn Smurthwaite, Heather A Coker, David J Fear, Graham K Banfield

J Immunol· April 2005

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Transcription of Ig germline genes in single human B cells and the role of cytokines in isotype determination.
David J Fear, Natalie McCloskey, Brian O'Connor, Gary Felsenfeld, Hannah J Gould

J Immunol· October 2004

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